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1.
Biochem Biophys Res Commun ; 460(4): 931-7, 2015 May 15.
Artigo em Inglês | MEDLINE | ID: mdl-25839659

RESUMO

During ischemia-reperfusion (IR) injury of the heart, Ca(2+) overload occurs, leading to cardiomyocyte dysfunction and eventual cell death by apoptosis. Since preventing Ca(2+) overload during IR injury has been reported to protect cardiomyocytes, interrupting Ca(2+) signaling cascades leading to Ca(2+) overload may exert protective effect on cardiomyocytes under hypoxic condition. One of the key regulators of the intracellular Ca(2+) level during IR injury is Na(+)-Ca(2+) exchanger 1 (NCX1), whose down-regulation during IR injury conferred protection of heart. In the present study, we examined whether down-regulation of NCX1 using exogenous microRNA ameliorates apoptosis of cardiomyocytes under hypoxic condition. Here, we identified miR-132 as a novel microRNA targeting the NCX1, whose expression increased during hypoxia. Delivery of miR-132 suppressed the increase of intracellular Ca(2+) in cardiomyocytes under hypoxia, and the expressions of apoptotic molecules, such as Bax, cytochrome C, and caspase 3, and the number of apoptotic cells were also decreased by exogenous miR-132 treatment. These results suggest the potential of miR-132 as an effective therapeutic agent against IR damage to heart by preventing Ca(2+) overload during hypoxic condition and warrant further studies to validate its anti-apoptotic effect in vivo.


Assuntos
Apoptose , Cálcio/metabolismo , MicroRNAs/metabolismo , Miócitos Cardíacos/metabolismo , Trocador de Sódio e Cálcio/metabolismo , Animais , Células Cultivadas , Miócitos Cardíacos/citologia , Ratos , Reação em Cadeia da Polimerase em Tempo Real
2.
Chemistry ; 21(16): 6165-72, 2015 Apr 13.
Artigo em Inglês | MEDLINE | ID: mdl-25739448

RESUMO

Silver nanoparticles (NPs) ranging in size from 40 to 100 nm were prepared in high yield by using an improved seed-mediated method. The homogeneous Ag NPs were used as building blocks for 2D assembled Ag NP arrays by using an oil/water interface. A close-packed 2D array of Ag NPs was fabricated by using packing molecules (3-mercaptopropyltrimethoxysilane) to control the interparticle spacing. The homogeneous 2D Ag NP array exhibited a strong quadrupolar cooperative plasmon mode resonance and a dipolar red-shift relative to individual Ag NPs suspended in solution. A well-arranged 2D Ag NP array was embedded in polydimethylsiloxane film and, with biaxial stretching to control the interparticle distance, concomitant variations of the quadrupolar and dipolar couplings were observed. As the interparticle distance increased, the intensity of the quadrupolar cooperative plasmon mode resonance decreased and dipolar coupling completely disappeared. The local electric field of the 2D Ag NP array was calculated by using finite difference time domain simulation and qualitatively showed agreement with the experimental measurements.

3.
J Am Chem Soc ; 136(50): 17674-80, 2014 Dec 17.
Artigo em Inglês | MEDLINE | ID: mdl-25412438

RESUMO

Surface plasmonics of nanomaterials has been one of the main research themes in nanoscience. Spherical and elongated nanoparticles show their corresponding unique optical features mainly depending on the physical dimensions. Here we successfully synthesized Au nanorings having Pt framework (Pt@Au nanorings) with high uniformity through wet-chemistry. The synthetic strategy consisted of serial reactions involving site-selective growth of Pt on the rim of Au nanoplates, subsequent etching of Au nanoplates, followed by regrowth of Au on the Pt rim. In this synthetic method, Au(3+) ions exhibited dual functionality as an etchant and a metal precursor. The resultant product, Pt@Au nanorings, exhibited unique localized surface plasmon resonance (LSPR) bands originating from the Au shell. The inner Pt skeleton turns out to be important to hold structural stability.

4.
J Chest Surg ; 57(3): 255-262, 2024 May 05.
Artigo em Inglês | MEDLINE | ID: mdl-38528758

RESUMO

Background: Sutureless aortic valves may enable shorter procedure times, which benefits patients with elevated surgical risk. We describe the outcomes of patients with aortic stenosis who underwent aortic valve replacement (AVR) using the sutureless Perceval aortic bioprosthesis. Methods: Data from a retrospective cohort were obtained from a clinical database. The study enrolled patients with symptomatic severe aortic stenosis who underwent surgical AVR with a sutureless bioprosthesis between August 2015 and December 2020. In total, 113 patients were included (mean age, 75.3±8.4 years; 57.5% women; median Society of Thoracic Surgeons score, 9.7%; mean follow-up period, 51.19±20.6 months). Of these patients, 41 were octogenarians (36.2%) and 3 were nonagenarians (2.6%). Transthoracic echocardiography was employed to assess changes in ejection fraction (EF), left ventricular mass index (LVMI), and mean pressure gradient (MPG). Results: The in-hospital mortality rate was 2.6%, and 13 patients developed new-onset atrial fibrillation. A permanent pacemaker was implanted in 3 patients (2.6%). The median intensive care unit stay was 1 day (interquartile range [IQR], 1-2 days), and the median hospital stay was 12 days (IQR, 9.5-15 days). The overall survival rate at 5 years was 95.9%. LVMI and MPG were reduced postoperatively, while EF increased over the follow-up period. No structural valve deterioration was observed, and no meaningful paravalvular leakage developed during follow-up. Conclusion: The use of a sutureless valve in the aortic position is safe and feasible, even for high-risk elderly patients requiring surgical AVR. LVMI and MPG decreased postoperatively, while EF increased over the follow-up period.

5.
J Clin Med ; 13(8)2024 Apr 11.
Artigo em Inglês | MEDLINE | ID: mdl-38673480

RESUMO

Background: Pain control after off-pump coronary artery bypass graft (OPCAB) facilitates mobilization and improves outcomes. The efficacy of the erector spinae plane block (ESPB) after cardiac surgery remains controversial. Methods: We aimed to investigate the analgesic effects of ESPB after OPCAB. Precisely 56 patients receiving OPCAB were randomly divided into ESPB and control groups. The primary outcome was visual analog scale (VAS) pain scores at 6, 12, 24, and 48 h postoperatively. Secondary outcomes were the dose of rescue analgesics in terms of oral morphine milligram equivalents, the dose of antiemetics, the length of intubation time, and the length of stay in the intensive care unit (ICU). Results: The VAS scores were similar at all time points in both groups. The incidence of severe pain (VAS score > 7) was significantly lower in the ESPB group (50% vs. 15.4%; p = 0.008). The dose of rescue analgesics was also lower in the ESPB group (19.04 ± 18.76, 9.83 ± 12.84, p = 0.044) compared with the control group. The other secondary outcomes did not differ significantly between the two groups. Conclusions: ESPB provides analgesic efficacy by reducing the incidence of severe pain and opioid use after OPCAB.

6.
J Surg Res ; 185(1): 166-73, 2013 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-23769631

RESUMO

BACKGROUND: We evaluated the effect of incomplete revascularization (IR) on the long-term outcomes after off-pump coronary artery bypass grafting. MATERIALS AND METHODS: Of 1553 patients with triple-vessel disease who had undergone consecutive off-pump coronary artery bypass grafting, 1351 (87.0%) had complete revascularization (CR) and 202 had IR (13.0%). After propensity score patient matching, we had 200 patients in each group. Cardiac survival and major adverse cardiac and cerebrovascular events (MACCE) were assessed before and after patient matching. Subgroup analysis was performed to evaluate the interaction between the left ventricular ejection fraction (LVEF) and the completeness of revascularization. The follow-up duration was 60 mo. RESULTS: In the all-patient analysis, the CR group had a lower incidence of in-hospital mortality, cardiac mortality, and MACCE (P = 0.033, P < 0.001, and P = 0.003, respectively). The 5-year cardiac survival was 96.5% ± 0.6% in the CR group and 88.9% ± 2.5% in the IR group (P < 0.001), with a freedom from MACCE rate of 85.4% ± 1.2% and 78.8% ± 3.4%, respectively (P = 0.015). After patient matching, the CR group showed superior 5-year cardiac survival compared with the IR group (96.2% ± 1.4% versus 88.8% ± 2.5%, P = 0.022), with a similar freedom from MACCE rate. IR was identified as an independent predictor of cardiac death (hazard ratio 2.76, 95% confidence interval 1.62-4.70; P < 0.001). IR predicted cardiac death more distinctly in patients with a low LVEF (hazard ratio 5.29, 95% confidence interval 1.71-16.39; P = 0.004) than in those with a preserved LVEF (hazard ratio 2.04, 95% confidence interval 1.02-4.08; P = 0.045). CONCLUSIONS: CR in off-pump coronary artery bypass grafting was related to superior cardiac survival after 5 years of follow-up compared with IR. The benefit of CR was more distinct in those with a low LVEF. CR should be achieved whenever possible, especially in patients with a low LVEF.


Assuntos
Ponte de Artéria Coronária sem Circulação Extracorpórea/efeitos adversos , Ponte de Artéria Coronária sem Circulação Extracorpórea/mortalidade , Doença da Artéria Coronariana , Circulação Coronária/fisiologia , Revascularização Miocárdica/efeitos adversos , Revascularização Miocárdica/mortalidade , Idoso , Doença da Artéria Coronariana/mortalidade , Doença da Artéria Coronariana/fisiopatologia , Doença da Artéria Coronariana/cirurgia , Feminino , Seguimentos , Mortalidade Hospitalar , Humanos , Incidência , Estimativa de Kaplan-Meier , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias/mortalidade , Estudos Retrospectivos , Fatores de Risco , Volume Sistólico/fisiologia , Resultado do Tratamento
7.
Langmuir ; 28(16): 6670-6, 2012 Apr 24.
Artigo em Inglês | MEDLINE | ID: mdl-22462572

RESUMO

We synthesized hollow Au-Ag nanospheres (NSs) by employing a galvanic replacement reaction between HAuCl4 and Ag NSs. Uniform Ag NSs with controllable sizes were synthesized as sacrificial templates by a seed-mediated strategy. The atomic ratio of Au to Ag in Au-Ag NSs was tunable by controlling the reagent concentration. UV-vis extinction spectra acquired from well-dispersed colloidal NS solutions were used to investigate the optical properties of the solutions. In addition to a common dipole mode exhibited on most transition metal nanoparticles, we observed a quadrupole plasmon resonance mode when the diameters of the Ag and Au-Ag NSs were larger than 100 nm. The quadrupole and dipole peaks both shifted to longer wavelengths with increased Au content in Au-Ag NSs. The experimental observation of optical properties of hollow Au-Ag NSs was compared with the theoretical simulation using DDA calculation, showing a good agreement.

8.
J Korean Med Sci ; 27(2): 153-9, 2012 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22323862

RESUMO

There is no consensus as to which acute myocardial infarction subtype poses a greater risk after coronary artery bypass grafting (CABG). We compared the early and the long term results of off-pump coronary artery bypass grafting (OPCAB) between patients with STEMI (group I, n = 83), and NSTEMI (group II, n = 237). Group I had higher EuroSCORE, prevalence of emergency surgery, preoperative intra-aortic balloon pump use, preoperative emergency percutaneous transluminal coronary angioplasty, and preoperative thrombolytic use than group II. There were no significant differences in 30-day mortality and major adverse cardiac and cerebrovascular event (MACCE) between groups. Overall 8-yr survival was 93% and 87% in groups I and II, respectively. Freedom from MACCE after 8 yr was 92% and 93% in groups I and II, respectively. After propensity score matching analysis, there were no significant differences in preoperative parameters, postoperative in-hospital outcomes, and long-term clinical outcomes. Surgical results of OPCAB in patients with acute myocardial infarction show good results in terms of long-term survival and freedom from MACCE, with no significant differences in clinical outcomes between STEMI and NSTEMI groups.


Assuntos
Ponte de Artéria Coronária sem Circulação Extracorpórea , Infarto do Miocárdio/cirurgia , Doença Aguda , Idoso , Angioplastia Coronária com Balão , Intervalo Livre de Doença , Eletrocardiografia , Feminino , Fibrinolíticos/uso terapêutico , Humanos , Masculino , Pessoa de Meia-Idade , Infarto do Miocárdio/tratamento farmacológico , Infarto do Miocárdio/mortalidade , Razão de Chances , Período Pré-Operatório , Pontuação de Propensão
9.
J Korean Med Sci ; 26(3): 444-6, 2011 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-21394316

RESUMO

Endovascular repair of inflammatory aortic aneurysms has been reported as an alternative to open surgical treatment. In selective cases, adjunctive bypass surgery may be required to provide an adequate landing zone. We report a case of endovascular repair of an inflammatory aortic aneurysm in a patient with Behçet's disease using a carotid-carotid bypass graft to provide an adequate landing zone. A 45-yr-old man with a voice change was referred to our hospital with the diagnosis of saccular aneurysm of the distal aortic arch resulting from vasculitis. Computed tomography showed a thoracic aortic aneurysm with thrombosis. Right to left carotid-carotid bypass grafting was performed. After 8 days, the patient underwent an endovascular stent graft placement distal to the origin of the innominate artery. The patient was discharged with medication and without postoperative complications after 5 days. Hybrid endovascular treatment may be suitable a complementary modality for repairing inflammatory aortic aneurysms.


Assuntos
Aneurisma da Aorta Torácica/cirurgia , Síndrome de Behçet/complicações , Implante de Prótese Vascular/métodos , Artérias Carótidas/cirurgia , Aneurisma da Aorta Torácica/complicações , Aneurisma da Aorta Torácica/diagnóstico por imagem , Síndrome de Behçet/cirurgia , Artérias Carótidas/fisiopatologia , Ponte de Artéria Coronária , Procedimentos Endovasculares , Humanos , Masculino , Pessoa de Meia-Idade , Radiografia , Stents , Trombose/complicações , Tomógrafos Computadorizados , Vasculite/complicações
10.
Medicine (Baltimore) ; 100(11): e25000, 2021 Mar 19.
Artigo em Inglês | MEDLINE | ID: mdl-33725973

RESUMO

ABSTRACT: This study evaluated the outcomes and prognostic factors for breast cancer according to initial lymph node (LN) status. Among patients with LN-negative breast cancer, we also focused on the prognostic value of estrogen receptor (ER) status.Medical records were retrospectively reviewed for 715 patients who underwent curative surgery for breast cancer between January 2005 and December 2015 at a single Korean institution. We evaluated factors that were associated with metastasis-free survival (MFS) according to LN status.Among the 715 patients (age: 28-87 years), 458 patients (64.1%) did not have axillary LN metastasis. Relative to patients without LN metastasis, patients with LN metastasis had larger tumor sizes and higher histological grades. Among patients with no LN metastasis, ER positivity was associated with non-significantly poorer MFS than ER negativity (mean survival: 138.90 months vs. 146.99 months, p = .17), and patients with LN-negative ER-positive disease had MFS rates of 91.7% at 5 years and 74.5% at 10 years. Among patients with LN-negative ER-positive disease, a poor prognosis was significantly associated with larger tumor size (≥2 cm, P = .03) and older age (≥50 years, P = .03).These results indicate that the risk of metastasis increases over time for patients with LN-negative ER-positive breast cancer, and especially for older patients or patients with larger tumors.


Assuntos
Neoplasias da Mama/metabolismo , Neoplasias da Mama/mortalidade , Receptores de Estrogênio/metabolismo , Adulto , Idoso , Idoso de 80 Anos ou mais , Povo Asiático/estatística & dados numéricos , Neoplasias da Mama/patologia , Feminino , Humanos , Linfonodos/patologia , Metástase Linfática , Pessoa de Meia-Idade , Prognóstico , Receptor ErbB-2/metabolismo , Receptores de Progesterona/metabolismo , República da Coreia , Estudos Retrospectivos , Taxa de Sobrevida , Carga Tumoral
11.
Circ J ; 74(6): 1121-6, 2010 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-20410619

RESUMO

BACKGROUND: Metabolic syndrome (MetS) is a clustering of risk factors, including dyslipidemia, hypertension, and increased plasma glucose levels, which increase the risk of cardiovascular disease and renal impairment. We retrospectively analyzed the relationship between MetS and acute kidney injury (AKI) after off-pump coronary artery bypass surgery (OPCAB). METHODS AND RESULTS: Patients who underwent isolated OPCAB between January 2006 and December 2008 were identified. Patients were grouped by using the National Cholesterol Education Program-Adult Treatment Panel III criteria with body mass index instead of waist circumference. From a total of 740 patients, 320 patients (43.2%) were in the MetS group, and 420 patients (56.8%) were in the non-MetS group. Postoperative AKI occurred in 84 patients (26.2%) in the MetS group and 44 patients (10.5%) in the non-MetS group (P<0.05). Multivariate logistic regression identified diabetes mellitus (odds ratio (OR), 1.83; 95% confidence interval (CI), 1.12-3.00; P=0.02), chronic kidney disease (OR, 4.79; 95%CI, 2.85-8.07; P<0.001), MetS (OR, 3.14; 95%CI, 1.79-5.49; P=0.001), and emergency surgery (OR, 5.08; 95%CI, 1.01-25.6; P=0.05) as independent risk factors for AKI after OPCAB. CONCLUSIONS: MetS is a prevalent risk factor for postoperative AKI after OPCAB, and aggressive treatments of its components could have reduced operative morbidity.


Assuntos
Injúria Renal Aguda/etiologia , Ponte de Artéria Coronária sem Circulação Extracorpórea/efeitos adversos , Síndrome Metabólica/complicações , Complicações Pós-Operatórias/etiologia , Idoso , Índice de Massa Corporal , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Fatores de Risco
12.
Int J Cardiovasc Imaging ; 36(2): 197-203, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-31659602

RESUMO

We aimed to evaluate the relationship between post-stent fractional flow reserve (FFR) and intravascular ultrasound (IVUS) parameters for stent optimization. IVUS and FFR measurements were performed in 101 coronary lesions after successful percutaneous coronary intervention (PCI). Quantitative IVUS parameters for stent optimization such as minimal intra-stent cross sectional area (CSA), proximal, and distal reference lumen CSA, and plaque burden (PB) at both edges of the stent related to the post-stent FFR. Mean post-stent FFR was 0.91 ± 0.06. Post-stent FFR ≤ 0.90 was observed in 46 (45.5%) lesions. The 55 lesions with post-stent FFR > 0.9 had larger proximal CSA (9.2 ± 2.9 mm2 vs. 7.4 ± 2.3 mm2, p = 0.001), distal reference lumen CSA (7.4 ± 2.7 mm2 vs. 6.3 ± 2.1 mm2, p = 0.017), minimum intra-stent lumen CSA (7.4 ± 2.5 mm2 vs. 6.1 ± 1.7 mm2, p = 0.004), and lower proximal reference PB (45 ± 8.2% vs. 50 ± 11%, p = 0.017) than did those with post-stent FFR ≤ 0.90. Post-stent FFR had an inverse correlation with age, left anterior descending artery (LAD) against non-LAD, and proximal reference PB and a positive correlation with pre-stent FFR, proximal and distal reference lumen CSA, and minimum intra-stent lumen CSA. Meanwhile, no correlation was found between post-stent FFR and stent length. Pre-stent FFR (ß = 0.544), proximal reference lumen CSA (ß = 0.530) and age (ß = - 0.251) were found to be independently associated with the post-stent FFR. Post-procedural FFR might partly reflect the appropriateness of PCI results in terms of the adequate expansion of the stent and full lesion coverage on IVUS.


Assuntos
Cateterismo Cardíaco , Doença da Artéria Coronariana/terapia , Reserva Fracionada de Fluxo Miocárdico , Intervenção Coronária Percutânea/instrumentação , Stents , Ultrassonografia de Intervenção , Idoso , Doença da Artéria Coronariana/diagnóstico por imagem , Doença da Artéria Coronariana/fisiopatologia , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Intervenção Coronária Percutânea/efeitos adversos , Valor Preditivo dos Testes , Desenho de Prótese , Estudos Retrospectivos , Fatores de Tempo , Resultado do Tratamento
13.
Korean Circ J ; 54(3): 138-139, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38506103
14.
Gut Liver ; 12(5): 555-561, 2018 09 15.
Artigo em Inglês | MEDLINE | ID: mdl-29699059

RESUMO

Background/Aims: Acute hepatic dysfunction combined with alcoholic hepatitis (AH) in alcoholic cirrhosis is related to hepatic hypo-perfusion secondary to intrahepatic necroinflammation, neoangiogenesis, and shunt. The hepatic vein arrival time (HVAT) assessed by microbubble contrast-enhanced ultrasonography (CEUS) is closely correlated with the severity of intrahepatic changes. We investigated the usefulness of HVAT to predict short-term mortality of AH in cirrhosis. Methods: Thirty-nine patients with alcoholic cirrhosis (27 males) and AH were prospectively enrolled. HVAT study was performed within 3 days after admission using ultrasonic contrast (SonoVue®). The primary outcome was 12-week mortality. Results: Twelve-week mortality developed in nine patients. HVAT was significantly different between the mortality and survival groups (9.3±2.0 seconds vs 12.6±3.5 seconds, p=0.002). The odds ratio of a shortened HVAT for 12-week mortality was 1.481 (95% confidence interval, 1.050-2.090; p=0.025). The area under the receiver operating characteristic curve of HVAT for 12-week mortality was 0.787 (p=0.010). The combination of MDF and HVAT ≥11.0 seconds resulted in an 87.5% survival rate even if the MDF score ≥32; however, HVAT <11.0 seconds was related with mortality despite a MDF score<32. Conclusions: HVAT using microbubble CEUS could be a useful additional index to predict short-term mortality in patients with AH and cirrhosis.


Assuntos
Veias Hepáticas/diagnóstico por imagem , Hepatite Alcoólica/diagnóstico por imagem , Cirrose Hepática Alcoólica/diagnóstico por imagem , Ultrassonografia/métodos , Adulto , Idoso , Área Sob a Curva , Meios de Contraste , Feminino , Hepatite Alcoólica/mortalidade , Humanos , Cirrose Hepática Alcoólica/mortalidade , Masculino , Pessoa de Meia-Idade , Fosfolipídeos , Projetos Piloto , Prognóstico , Estudos Prospectivos , Curva ROC , Hexafluoreto de Enxofre , Fatores de Tempo
15.
Yonsei Med J ; 59(1): 57-62, 2018 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-29214777

RESUMO

PURPOSE: Obesity is often associated with better clinical outcomes in heart failure (HF). This so-called obesity paradox remains controversial. The aim of present study was to investigate the prognostic value of obesity in patients hospitalized for systolic HF. MATERIALS AND METHODS: We performed a pooled analysis of data from two multicenter, observational HF studies. Patients hospitalized for systolic HF were eligible for the present study. We divided the subjects into two groups, a normal body mass index (BMI) group and a high BMI group. Study endpoints included all-cause mortality and any re-hospitalization within 1 year. RESULTS: We enrolled 3145 patients (male, 1824; female, 1321). The high BMI group was significantly associated with lower 1-year mortality rate [odds ratio (OR), 0.543; 95% confidence interval (CI), 0.355-0.832] after adjusting for age, hypertension, diabetes, ischemic HF, previous myocardial infarction, serum creatinine level, anemia, and ejection fraction in men. After adjustment for clinical characteristics, high BMI was not significantly associated with 1-year mortality (OR, 0.739; 95% CI, 0.450-1.216) or 1-year re-hospitalization (OR, 0.958; 95% CI, 0.696-1.319) in women. CONCLUSION: In pooled analysis of data from two Korean HF registries, the high BMI group was independently associated with lower 1-year mortality rate from systolic HF, especially in men.


Assuntos
Insuficiência Cardíaca Sistólica/complicações , Insuficiência Cardíaca Sistólica/epidemiologia , Obesidade/complicações , Obesidade/epidemiologia , Caracteres Sexuais , Idoso , Índice de Massa Corporal , Demografia , Determinação de Ponto Final , Feminino , Humanos , Incidência , Estimativa de Kaplan-Meier , Masculino , Pessoa de Meia-Idade , Resultado do Tratamento
16.
Korean J Thorac Cardiovasc Surg ; 50(6): 474-476, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-29234619

RESUMO

A 56-year-old woman, who underwent cardiac surgery 3 months previously, presented to the emergency room with pulmonary artery rupture due to the cytotoxic effects of BioGlue (CryoLife Inc., Kennesaw, GA, USA). She was successfully treated with surgical management. Although surgical glue can be effectively used for hemostasis, it can induce delayed vascular complications. Therefore, surgical glue should be used cautiously.

18.
J Colloid Interface Sci ; 461: 376-382, 2016 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-26414420

RESUMO

Herein, we report the surface plasmon resonance of plasmonic multi-shell nanoparticles compared to bimetallic Ag/Au hollow nanospheres of similar final size, shape, and percent composition. The surface plasmon resonance of solid and hollow nanoparticles exhibited a quadrupole mode that was particularly prominent around the 100 nm size regime, while multi-shell nanoparticles did not show a quadrupole mode at a similar size. In the latter case, the quadrupole mode of the outermost nanoshell was suppressed by the dipole modes of the inner shells, and the suppression of the quadrupole mode was not affected by the shape of the inner nanostructures. Light interaction of the multi-shell nanoparticle was investigated through simulated electromagnetic field distribution obtained by finite-difference time domain (FDTD) calculations which were in a good agreement with the results of surface-enhanced Raman spectroscopy (SERS).

19.
Nanoscale ; 8(8): 4491-4, 2016 Feb 28.
Artigo em Inglês | MEDLINE | ID: mdl-26859224

RESUMO

We report a facile method to synthesize elongated nanoframes consisting of Pt and Au in solution. Pentagonal Au nanorods served as templates and successfully led to an elongated AuPt nanoframe after etching the core Au. Subsequently, the coating of Au around Pt ridges resulted in Pt@Au metal nanoframes. The resulting elongated nanostructure exhibited 5 well-defined ridges continuously connected along the long axis. During the shape evolution from pure Au nanorods to elongated Pt@Au metal nanoframes, their corresponding localized surface plasmon resonance bands were monitored. Especially, unique surface plasmon features were observed for elongated Pt@Au nanoframes where the short-axis oscillation of surface free electrons is strongly coupled but the long-axis oscillation is not coupled among the ridges.

20.
Nanoscale ; 6(13): 7339-45, 2014 Jul 07.
Artigo em Inglês | MEDLINE | ID: mdl-24861989

RESUMO

In this report, we tune the surface plasmonic behavior of Au nanoplates depending on the morphology of the Pt shell in which Pt is considered as a less optically inactive element. We describe the synthesis of flat Au nanoplates coated with Pt via rim-preferential or uniform growth methods. Depending on the site-selective growth of Pt on core Au nanoplates, the aspect ratio of the resulting Au@Pt nanoplates was tunable and their corresponding surface plasmon resonance (SPR) bands were controlled accordingly. Although Pt is regarded as an optically weak component in visible and near infrared spectral windows, a Pt coating affects the SPR behavior of core Au nanoplates due to effective surface plasmon (SP) coupling between the Au core and the deposited Pt shell. We systematically investigated the optical properties of uniformly grown (Au@Pt(uni)) and rim-preferentially grown (Au@Pt(rim)) Au@Pt nanoplates by observing their SPR band shifts compared to SPR of Au nanoplates. Due to the structural rigidity conferred by the Pt coating, the Au@Pt nanoplates can be easily transferred to the investigated solvents.

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