Detalhe da pesquisa
1.
IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression.
Cell
; 182(5): 1252-1270.e34, 2020 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32818467
2.
Alzheimer's-Causing Mutations Shift Aß Length by Destabilizing γ-Secretase-Aßn Interactions.
Cell
; 170(3): 443-456.e14, 2017 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28753424
3.
Alzheimer's-causing mutations shift Aß length by destabilizing γ-secretase-Aßn interactions.
Cell
; 184(8): 2257-2258, 2021 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33861967
4.
APP substrate ectodomain defines amyloid-ß peptide length by restraining γ-secretase processivity and facilitating product release.
EMBO J
; 42(23): e114372, 2023 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37853914
5.
Enzyme-substrate interface targeting by imidazole-based γ-secretase modulators activates γ-secretase and stabilizes its interaction with APP.
EMBO J
; 41(21): e111084, 2022 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36121025
6.
pyM2aia: Python interface for mass spectrometry imaging with focus on deep learning.
Bioinformatics
; 40(3)2024 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38445753
7.
High-Throughput Miniaturized Synthesis of PROTAC-Like Molecules.
Small
; : e2307215, 2024 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38258390
8.
PerSurge (NOA-30) phase II trial of perampanel treatment around surgery in patients with progressive glioblastoma.
BMC Cancer
; 24(1): 135, 2024 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38279087
9.
Nanoliter Scale Parallel Liquid-Liquid Extraction for High-Throughput Purification on a Droplet Microarray.
Small
; 19(9): e2204512, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36538723
10.
A Caged In-Source Laser-Cleavable MALDI Matrix with High Vacuum Stability for Extended MALDI-MS Imaging.
Angew Chem Int Ed Engl
; 62(22): e202217047, 2023 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36757677
11.
Structural amyloid plaque polymorphism is associated with distinct lipid accumulations revealed by trapped ion mobility mass spectrometry imaging.
J Neurochem
; 160(4): 482-498, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34882796
12.
Spatially resolved mass spectrometry analysis of amyloid plaque-associated lipids.
J Neurochem
; 159(2): 330-342, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33048341
13.
Recent developments of novel matrices and on-tissue chemical derivatization reagents for MALDI-MSI.
Anal Bioanal Chem
; 413(10): 2599-2617, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33215311
14.
Spatial Distribution of Endogenous Tissue Protease Activity in Gastric Carcinoma Mapped by MALDI Mass Spectrometry Imaging.
Mol Cell Proteomics
; 18(1): 151-161, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30293968
15.
Fast Quantification Without Conventional Chromatography, The Growing Power of Mass Spectrometry.
Anal Chem
; 92(13): 8628-8637, 2020 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32510944
16.
New Derivatization Reagent for Detection of free Thiol-groups in Metabolites and Proteins in Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging.
Anal Chem
; 92(9): 6224-6228, 2020 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32233426
17.
Computational Analysis of Alzheimer Amyloid Plaque Composition in 2D- and Elastically Reconstructed 3D-MALDI MS Images.
Anal Chem
; 92(21): 14484-14493, 2020 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33138378
18.
Direct Automated MALDI Mass Spectrometry Analysis of Cellular Transporter Function: Inhibition of OATP2B1 Uptake by 294 Drugs.
Anal Chem
; 92(17): 11851-11859, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32867487
19.
Clinically Relevant OATP2B1 Inhibitors in Marketed Drug Space.
Mol Pharm
; 17(2): 488-498, 2020 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31834804
20.
Bacterial immunogenic α-galactosylceramide identified in the murine large intestine: dependency on diet and inflammation.
J Lipid Res
; 60(11): 1892-1904, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31484693