Detalhe da pesquisa
1.
Reduced serotonergic transmission alters sensitivity to cost and reward via 5-HT1A and 5-HT1B receptors in monkeys.
PLoS Biol
; 22(1): e3002445, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38163325
2.
Multimodal Imaging for Validation and Optimization of Ion Channel-Based Chemogenetics in Nonhuman Primates.
J Neurosci
; 43(39): 6619-6627, 2023 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37620158
3.
Photo-oxygenation of histidine residue inhibits α-synuclein aggregation.
FASEB J
; 37(12): e23311, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37962096
4.
D1- and D2-like receptors differentially mediate the effects of dopaminergic transmission on cost-benefit evaluation and motivation in monkeys.
PLoS Biol
; 19(7): e3001055, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34197448
5.
Chronic Behavioral Manipulation via Orally Delivered Chemogenetic Actuator in Macaques.
J Neurosci
; 42(12): 2552-2561, 2022 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35110390
6.
Chemogenetic Disconnection between the Orbitofrontal Cortex and the Rostromedial Caudate Nucleus Disrupts Motivational Control of Goal-Directed Action.
J Neurosci
; 42(32): 6267-6275, 2022 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35794012
7.
GPR120 signaling controls amyloid-ß degrading activity of matrix metalloproteinases.
J Neurosci
; 2021 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34099509
8.
Photo-oxygenation by a biocompatible catalyst reduces amyloid-ß levels in Alzheimer's disease mice.
Brain
; 144(6): 1884-1897, 2021 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33851209
9.
EphA4 regulates Aß production via BACE1 expression in neurons.
FASEB J
; 34(12): 16383-16396, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33090569
10.
Identification of calcium and integrin-binding protein 1 as a novel regulator of production of amyloid ß peptide using CRISPR/Cas9-based screening system.
FASEB J
; 34(6): 7661-7674, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32307772
11.
Photo-Oxygenation: An Innovative New Therapeutic Approach Against Amyloidoses.
Adv Exp Med Biol
; 1339: 415-422, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35023134
12.
Signaling Incentive and Drive in the Primate Ventral Pallidum for Motivational Control of Goal-Directed Action.
J Neurosci
; 39(10): 1793-1804, 2019 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30626695
13.
CD2-associated protein (CD2AP) overexpression accelerates amyloid precursor protein (APP) transfer from early endosomes to the lysosomal degradation pathway.
J Biol Chem
; 294(28): 10886-10899, 2019 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31138646
14.
Retrograde transport of γ-secretase from endosomes to the trans-Golgi network regulates Aß42 production.
J Neurochem
; 147(1): 110-123, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29851073
15.
Partial loss of CALM function reduces Aß42 production and amyloid deposition in vivo.
Hum Mol Genet
; 25(18): 3988-3997, 2016 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27466196
16.
BIN1 regulates BACE1 intracellular trafficking and amyloid-ß production.
Hum Mol Genet
; 25(14): 2948-2958, 2016 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27179792
17.
Roles of centromedian parafascicular nuclei of thalamus and cholinergic interneurons in the dorsal striatum in associative learning of environmental events.
J Neural Transm (Vienna)
; 125(3): 501-513, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28324169
18.
Role of Apolipoprotein E in ß-Amyloidogenesis: ISOFORM-SPECIFIC EFFECTS ON PROTOFIBRIL TO FIBRIL CONVERSION OF Aß IN VITRO AND BRAIN Aß DEPOSITION IN VIVO.
J Biol Chem
; 290(24): 15163-74, 2015 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25918154
19.
A Food and Drug Administration-approved asthma therapeutic agent impacts amyloid ß in the brain in a transgenic model of Alzheimer disease.
J Biol Chem
; 290(4): 1966-78, 2015 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25468905
20.
Anti-ApoE antibody given after plaque onset decreases Aß accumulation and improves brain function in a mouse model of Aß amyloidosis.
J Neurosci
; 34(21): 7281-92, 2014 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24849360