Detalhe da pesquisa
1.
fMRI study of olfactory processing in mice under three anesthesia protocols: Insight into the effect of ketamine on olfactory processing.
Neuroimage
; 213: 116725, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32173412
2.
fMRI study of the role of glutamate NMDA receptor in the olfactory adaptation in rats: Insights into cellular and molecular mechanisms of olfactory adaptation.
Neuroimage
; 149: 348-360, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28163142
3.
Discovery of selective, orally bioavailable, N-linked arylsulfonamide Nav1.7 inhibitors with pain efficacy in mice.
Bioorg Med Chem Lett
; 27(10): 2087-2093, 2017 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28389149
4.
Benzoxazolinone aryl sulfonamides as potent, selective Nav1.7 inhibitors with in vivo efficacy in a preclinical pain model.
Bioorg Med Chem Lett
; 27(12): 2683-2688, 2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28465103
5.
fMRI study of olfaction in the olfactory bulb and high olfactory structures of rats: Insight into their roles in habituation.
Neuroimage
; 127: 445-455, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26522425
6.
Functional imaging of olfaction by CBV fMRI in monkeys: insight into the role of olfactory bulb in habituation.
Neuroimage
; 106: 364-72, 2015 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25498426
7.
Association of respiratory failure with inhibition of NaV1.6 in the phrenic nerve.
Channels (Austin)
; 16(1): 230-243, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36239534
8.
Translational Pharmacokinetic-Pharmacodynamic Modeling of NaV1.7 Inhibitor MK-2075 to Inform Human Efficacious Dose.
Front Pharmacol
; 12: 786078, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35002718
9.
Discovery of Arylsulfonamide Nav1.7 Inhibitors: IVIVC, MPO Methods, and Optimization of Selectivity Profile.
ACS Med Chem Lett
; 12(6): 1038-1049, 2021 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34141090
10.
Nav1.7 target modulation and efficacy can be measured in nonhuman primate assays.
Sci Transl Med
; 13(594)2021 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34011626
11.
Design, synthesis, and structure-activity relationship study of conformationally constrained analogs of indole-3-carboxamides as novel CB1 cannabinoid receptor agonists.
Bioorg Med Chem Lett
; 20(16): 4918-21, 2010 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20634067
12.
Design, synthesis, and structure-activity relationship study of bicyclic piperazine analogs of indole-3-carboxamides as novel cannabinoid CB1 receptor agonists.
Bioorg Med Chem Lett
; 20(24): 7327-30, 2010 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21074434
13.
Rapid access towards follow-up NOP receptor agonists using a knowledge based approach.
Bioorg Med Chem Lett
; 19(22): 6441-6, 2009 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19818611
14.
Structure-activity relationships and CoMFA of N-3 substituted phenoxypropyl piperidine benzimidazol-2-one analogues as NOP receptor agonists with analgesic properties.
Bioorg Med Chem
; 16(6): 2829-51, 2008 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18249547
15.
Pharmacological validation of a novel nonhuman primate measure of thermal responsivity with utility for predicting analgesic effects.
J Pain Res
; 11: 735-741, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29692626
16.
fMRI study of the role of glutamate NMDA receptor in the olfactory processing in monkeys.
PLoS One
; 13(6): e0198395, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29870538
17.
The hypnotic, electroencephalographic, and antinociceptive properties of nonpeptide ORL1 receptor agonists after intravenous injection in rodents.
Anesth Analg
; 104(1): 174-9, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17179266
18.
Dorsal column lesion prevents mechanical hyperalgesia and allodynia in osteotomy model.
Pain
; 82(1): 73-80, 1999 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-10422662
19.
Enhanced withdrawal responses to mechanical and thermal stimuli after bone injury.
Pain
; 73(3): 325-337, 1997 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-9469522
20.
The involvement of bulbospinal pathways in fentanyl-induced inhibition of spinal withdrawal reflexes in the decerebrated rabbit.
Pain
; 78(3): 197-207, 1998 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-9870573