RESUMO
In a repeated-measures experiment 18 men and 8 women were given ethanol which raised their mean blood alcohol concentration (BAC) to 0, 21, 50 and 73 mg/100 ml. Using the ERM apparatus (Schuhfried Instruments, Austria), which measures choice reaction time to a task with high cognitive content, it was found that both decision and reaction time increased as a function of rising BAC, and that movement time was not affected.
Assuntos
Consumo de Bebidas Alcoólicas , Comportamento de Escolha/efeitos dos fármacos , Cognição/efeitos dos fármacos , Tempo de Reação/efeitos dos fármacos , Adolescente , Adulto , Tomada de Decisões/efeitos dos fármacos , Relação Dose-Resposta a Droga , Etanol/sangue , Feminino , Humanos , Masculino , Rememoração Mental/efeitos dos fármacos , Destreza Motora/efeitos dos fármacosRESUMO
Wernicke's encephalopathy (WE) is a serious disease resulting from excessive alcohol intake. As well as the disastrous consequences for the individual, patients with WE place a heavy burden for continuing care on the community. Australia appears to have a higher rate of WE than other western countries, probably due to differences in the consumption patterns of alcoholic beverages. Unlike most other western countries, Australia does not fortify flour with thiamin. On the other hand the USA does fortify flour and has higher thiamin intakes and lower rates of WE. In Australia it has been proposed that thiamin be added to alcoholic beverages. Given that technical problems related to stability, taste and absorption can be solved, the fortification of a substance which is potentially harmful, raises serious problems for health educators. The labeling of alcoholic beverages as 'vitamin enriched' could result in changes in the community's beliefs about alcohol and in increased alcohol consumption. The nutrition and education implications of this proposal are discussed. The conclusion is drawn that Australia should follow the example of other western countries and fortify flour with thiamin.
Assuntos
Cerveja , Alimentos Fortificados , Promoção da Saúde , Encefalopatia de Wernicke/dietoterapia , Austrália , Feminino , Humanos , Masculino , Opinião Pública , Encefalopatia de Wernicke/epidemiologiaRESUMO
The summer alcohol consumption of women living in metropolitan Perth was measured using both a retrospective and prospective diary. Overall, 1356 women fully completed both the retrospective and prospective alcohol consumption diaries. The prospective diary yielded a significantly higher level (9%) of consumption (p less than 0.00001) compared with the retrospective diary. Although there was no significant difference in the percentage of women drinking at harmful levels (greater than 280 g absolute alcohol per week) between the two diary methods, there did appear to be an important percentage difference (1.9% versus 2.8%) suggesting that the prospective diary did detect a larger percentage of women at risk. This would be both practically and statistically significant in large populations. The heavier the drinker the greater the variability in reported consumption between the two diary weeks. However, it is interesting to note that the direction of the variation depended on which diary was used as the base for classifying women as different types of drinkers. Women who drank at hazardous (140-280 g per week) or harmful (greater than 280 g) levels during the retrospective diary week reported a lower level of consumption during the prospective diary week. Conversely women who drank at hazardous or harmful levels during the prospective diary week reported a lower level of consumption during the retrospective diary week. Possible explanations for these findings are explored and methodological considerations for future studies are discussed.