Detalhe da pesquisa
1.
A novel HDAC6 inhibitor interferes microtubule dynamics and spindle assembly checkpoint and sensitizes cisplatin-induced apoptosis in castration-resistant prostate cancer.
Prostate
; 84(6): 605-619, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38375594
2.
Mechanistic study of dual-function inhibitors targeting topoisomerase II and Rad51-mediated DNA repair pathway against castration-resistant prostate cancer.
Prostate
; 83(16): 1549-1563, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37583103
3.
Inhibitor development of MTH1 via high-throughput screening with fragment based library and MTH1 substrate binding cavity.
Bioorg Chem
; 110: 104813, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33774493
4.
Autophagic Activation and Decrease of Plasma Membrane Cholesterol Contribute to Anticancer Activities in Non-Small Cell Lung Cancer.
Molecules
; 26(19)2021 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34641511
5.
Ascleposide, a natural cardenolide, induces anticancer signaling in human castration-resistant prostatic cancer through Na+ /K+ -ATPase internalization and tubulin acetylation.
Prostate
; 80(4): 305-318, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31905252
6.
Mechanistic Study of Triazole Based Aminodiol Derivatives in Leukemic Cells-Crosstalk between Mitochondrial Stress-Involved Apoptosis and Autophagy.
Int J Mol Sci
; 21(7)2020 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32252439
7.
Discovery of Novel Agents on Spindle Assembly Checkpoint to Sensitize Vinorelbine-Induced Mitotic Cell Death Against Human Non-Small Cell Lung Cancers.
Int J Mol Sci
; 21(16)2020 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32764382
8.
Chalcones Display Anti-NLRP3 Inflammasome Activity in Macrophages through Inhibition of Both Priming and Activation Steps-Structure-Activity-Relationship and Mechanism Studies.
Molecules
; 25(24)2020 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33339319
9.
The (+)-Brevipolide H Displays Anticancer Activity against Human Castration-Resistant Prostate Cancer: The Role of Oxidative Stress and Akt/mTOR/p70S6K-Dependent Pathways in G1 Checkpoint Arrest and Apoptosis.
Molecules
; 25(12)2020 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32630532
10.
Genome-wide identification and characterization of TCP genes involved in ovule development of Phalaenopsis equestris.
J Exp Bot
; 67(17): 5051-66, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27543606
11.
Repurposing of phentolamine as a potential anticancer agent against human castration-resistant prostate cancer: A central role on microtubule stabilization and mitochondrial apoptosis pathway.
Prostate
; 75(13): 1454-66, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26180030
12.
KUD773, a phenylthiazole derivative, displays anticancer activity in human hormone-refractory prostate cancers through inhibition of tubulin polymerization and anti-Aurora A activity.
J Biomed Sci
; 22: 2, 2015 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25563361
13.
Moniliformediquinone induces in vitro and in vivo antitumor activity through glutathione involved DNA damage response and mitochondrial stress in human hormone refractory prostate cancer.
J Urol
; 191(5): 1429-38, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24316097
14.
Doxazosin inhibits vasculogenic mimicry in human nonsmall cell lung cancer through inhibition of the VEGFA/VEcadherin/mTOR/MMP pathway.
Oncol Lett
; 27(4): 170, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38455663
15.
Cardenolide glycosides sensitize gefitinib-induced apoptosis in non-small cell lung cancer: inhibition of Na+/K+-ATPase serving as a switch-on mechanism.
Naunyn Schmiedebergs Arch Pharmacol
; 2024 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38451282
16.
A novel hydroxysuberamide derivative potentiates MG132-mediated anticancer activity against human hormone refractory prostate cancers--the role of histone deacetylase and endoplasmic reticulum stress.
Prostate
; 73(12): 1270-80, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23813634
17.
Ardisianone, a natural benzoquinone, efficiently induces apoptosis in human hormone-refractory prostate cancers through mitochondrial damage stress and survivin downregulation.
Prostate
; 73(2): 133-45, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22674285
18.
Diploid and tetraploid genomes of Acorus and the evolution of monocots.
Nat Commun
; 14(1): 3661, 2023 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37339946
19.
The Combination of a Novel GLUT1 Inhibitor and Cisplatin Synergistically Inhibits Breast Cancer Cell Growth By Enhancing the DNA Damaging Effect and Modulating the Akt/mTOR and MAPK Signaling Pathways.
Front Pharmacol
; 13: 879748, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35662690
20.
Genomes of leafy and leafless Platanthera orchids illuminate the evolution of mycoheterotrophy.
Nat Plants
; 8(4): 373-388, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35449401