Detalhe da pesquisa
1.
Mechanical regulation of stem-cell differentiation by the stretch-activated Piezo channel.
Nature
; 555(7694): 103-106, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29414942
2.
Unexpected Cascade Sequence Forming the C(sp3)-N/C(sp2)-C(sp2) Bond: Direct Access to γ-Lactam-Fused Pyridones with Anticancer Activity.
J Org Chem
; 88(13): 7998-8009, 2023 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37279456
3.
Pharmacological Targeting of Bcl-2 Induces Caspase 3-Mediated Cleavage of HDAC6 and Regulates the Autophagy Process in Colorectal Cancer.
Int J Mol Sci
; 24(7)2023 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37047634
4.
Compound 275# Induces Mitochondria-Mediated Apoptosis and Autophagy Initiation in Colorectal Cancer Cells through an Accumulation of Intracellular ROS.
Molecules
; 28(7)2023 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37049976
5.
Multifunctional Novel Nanoplatform for Effective Synergistic Chemo-Photodynamic Therapy of Breast Cancer by Enhancing DNA Damage and Disruptions of Its Reparation.
Molecules
; 28(19)2023 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37836815
6.
Pyrrolyldihydropyrazino[1,2-a]indoletrione Analogue Microtubule Inhibitor Induces Cell-Cycle Arrest and Apoptosis in Colorectal Cancer Cells.
Molecules
; 28(4)2023 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36838936
7.
LMNA Reduced Acquired Resistance to Erlotinib in NSCLC by Reversing the Epithelial-Mesenchymal Transition via the FGFR/MAPK/c-fos Signaling Pathway.
Int J Mol Sci
; 23(21)2022 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36362025
8.
Antiproliferative Evaluation of Novel 4-Imidazolidinone Derivatives as Anticancer Agent Which Triggers ROS-Dependent Apoptosis in Colorectal Cancer Cell.
Molecules
; 27(24)2022 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36557977
9.
Demethylzeylasteral (T-96) initiates extrinsic apoptosis against prostate cancer cells by inducing ROS-mediated ER stress and suppressing autophagic flux.
Biol Res
; 54(1): 27, 2021 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34488902
10.
Future perspective: high-throughput construction of new ultrasensitive cytokine and virion liquid chips for high-throughput screening (HTS) of anti-inflammatory drugs or clinical diagnosis and treatment of inflammatory diseases.
Anal Bioanal Chem
; 412(28): 7685-7699, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32870351
11.
Development of an optimized synthetic Notch receptor as an in vivo cell-cell contact sensor.
Proc Natl Acad Sci U S A
; 114(21): 5467-5472, 2017 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28490499
12.
Diversity-Oriented Synthesis of Imidazo-Dipyridines with Anticancer Activity via the Groebke-Blackburn-Bienaymé and TBAB-Mediated Cascade Reaction in One Pot.
J Org Chem
; 84(19): 12632-12638, 2019 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31357859
13.
A Derivate of Benzimidazole-Isoquinolinone Induces SKP2 Transcriptional Inhibition to Exert Anti-Tumor Activity in Glioblastoma Cells.
Molecules
; 24(15)2019 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31357480
14.
Myc inhibits JNK-mediated cell death in vivo.
Apoptosis
; 22(4): 479-490, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28150056
15.
Lentivirus-mediated silencing of CNTN1 enhances gefitinib sensitivity by reversing epithelial-mesenchymal transition in lung adenocarcinoma A549 cells.
Oncol Lett
; 21(6): 433, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-33868471
16.
Smart Design of Mitochondria-Targeted and ROS-Responsive CPI-613 Delivery Nanoplatform for Bioenergetic Pancreatic Cancer Therapy.
Nanomaterials (Basel)
; 11(11)2021 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34835640
17.
DMAPTD6 induces deathreceptormediated apoptosis to inhibit glioblastoma cell oncogenesis via induction of DNA damage through accumulation of intracellular ROS.
Oncol Rep
; 45(3): 1261-1272, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33469671
18.
A Novel Imidazopyridine Derivative Exerts Anticancer Activity by Inducing Mitochondrial Pathway-Mediated Apoptosis.
Biomed Res Int
; 2020: 4929053, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32908894
19.
CPI-613 rewires lipid metabolism to enhance pancreatic cancer apoptosis via the AMPK-ACC signaling.
J Exp Clin Cancer Res
; 39(1): 73, 2020 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32345326
20.
A Novel Imidazopyridine Derivative Exhibits Anticancer Activity in Breast Cancer by Inhibiting Wnt/ßcatenin Signaling.
Onco Targets Ther
; 13: 10111-10121, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33116593