Detalhe da pesquisa
1.
Drugs/agents for the treatment of ischemic stroke: Advances and perspectives.
Med Res Rev
; 44(3): 975-1012, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38126568
2.
Synthesis and biological evaluation of hybrids from optically active ring-opened 3-N-butylphthalide derivatives and 4-fluro-edaravone as potential anti-acute ischemic stroke agents.
Bioorg Med Chem
; 69: 116891, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35764031
3.
Correction: Synthesis and biological evaluation of hybrids from farnesylthiosalicylic acid and hydroxylcinnamic acid with dual inhibitory activities of Ras-related signaling and phosphorylated NF-κB.
Org Biomol Chem
; 19(2): 486, 2021 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33393555
4.
Riboflavin Is Directly Involved in N-Dealkylation Catalyzed by Bacterial Cytochrome P450 Monooxygenases.
Chembiochem
; 21(16): 2297-2305, 2020 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32243060
5.
Nanoscale Coordination Polymers for Synergistic NO and Chemodynamic Therapy of Liver Cancer.
Nano Lett
; 19(4): 2731-2738, 2019 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30919635
6.
Fasudil dichloroacetate (FDCA), an orally available agent with potent therapeutic efficiency on monocrotaline-induced pulmonary arterial hypertension rats.
Bioorg Med Chem Lett
; 29(14): 1812-1818, 2019 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31088713
7.
Chemotaxis-Instructed Intracellular Staphylococcus aureus Infection Detection by a Targeting and Self-Assembly Signal-Enhanced Photoacoustic Probe.
Nano Lett
; 18(10): 6229-6236, 2018 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30153415
8.
Metal-Free Synthesis of N-(Pyridine-2-yl)amides from Ketones via Selective Oxidative Cleavage of C(O)-C(Alkyl) Bond in Water.
J Org Chem
; 83(23): 14307-14313, 2018 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30450904
9.
Novel Hsp90 inhibitor platycodin D disrupts Hsp90/Cdc37 complex and enhances the anticancer effect of mTOR inhibitor.
Toxicol Appl Pharmacol
; 330: 65-73, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28711525
10.
Novel anticancer oridonin derivatives possessing a diazen-1-ium-1,2-diolate nitric oxide donor moiety: Design, synthesis, biological evaluation and nitric oxide release studies.
Bioorg Med Chem Lett
; 26(12): 2795-2800, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27158140
11.
A novel GSK-3ß inhibitor YQ138 prevents neuronal injury induced by glutamate and brain ischemia through activation of the Nrf2 signaling pathway.
Acta Pharmacol Sin
; 37(6): 741-52, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27108601
12.
NSAIDs do not require the presence of a carboxylic acid to exert their anti-inflammatory effect - why do we keep using it?
J Enzyme Inhib Med Chem
; 31(6): 1018-28, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26403939
13.
Totarol prevents neuronal injury in vitro and ameliorates brain ischemic stroke: Potential roles of Akt activation and HO-1 induction.
Toxicol Appl Pharmacol
; 289(2): 142-54, 2015 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26440581
14.
Telmisartan prevention of LPS-induced microglia activation involves M2 microglia polarization via CaMKKß-dependent AMPK activation.
Brain Behav Immun
; 50: 298-313, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26188187
15.
Novel hybrids of 3-n-butylphthalide and edaravone: Design, synthesis and evaluations as potential anti-ischemic stroke agents.
Bioorg Med Chem Lett
; 25(17): 3535-40, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26189079
16.
The edaravone and 3-n-butylphthalide ring-opening derivative 10b effectively attenuates cerebral ischemia injury in rats.
Acta Pharmacol Sin
; 36(8): 917-27, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26073328
17.
Correction to Nanoscale Coordination Polymers for Synergistic NO and Chemodynamic Therapy of Liver Cancer.
Nano Lett
; 19(11): 8342, 2019 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31613100
18.
Synthesis and biological evaluation of hybrids from farnesylthiosalicylic acid and hydroxylcinnamic acid with dual inhibitory activities of Ras-related signaling and phosphorylated NF-κB.
Org Biomol Chem
; 12(25): 4517-30, 2014 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24848877
19.
Design, synthesis and biological evaluation of hydrogen sulfide releasing derivatives of 3-n-butylphthalide as potential antiplatelet and antithrombotic agents.
Org Biomol Chem
; 12(31): 5995-6004, 2014 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24988475
20.
Effective virtual screening strategy toward covalent ligands: identification of novel NEDD8-activating enzyme inhibitors.
J Chem Inf Model
; 54(6): 1785-97, 2014 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24857708