RESUMO
Potassium ion channels are essential elements in cellular electrical excitability and help maintain a resting potential in nonexcitable cells. Their universality is based on a unique combination of strong selectivity for K^{+} ions and near-diffusion-limited permeation efficiency. Understanding how the channel regulates the ion conduction would be instructive to the treatment of ion channelopathies. In this work, by means of molecular dynamics simulations, we demonstrate the significantly enhanced permeation of KcsA channel in reaction to an external terahertz wave, due to the effective response of the K^{+} ions in the selectivity filter regions of the channel. Compared to the case without external terahertz wave, a fourfold increase in the ion current through the channel is found.
RESUMO
An accurate understanding of ion-beam transport in plasmas is crucial for applications in inertial fusion energy and high-energy-density physics. We present an experimental measurement on the energy spectrum of a proton beam at 270 keV propagating through a gas-discharge hydrogen plasma. We observe the energies of the beam protons changing as a function of the plasma density and spectrum broadening due to a collective beam-plasma interaction. Supported by linear theory and three-dimensional particle-in-cell simulations, we attribute this energy modulation to a two-stream instability excitation and further saturation by beam ion trapping in the wave. The widths of the energy spectrum from both experiment and simulation agree with the theory.