Detalhe da pesquisa
1.
Stable overexpression of pregnane X receptor in HepG2 cells increases its potential for bioartificial liver application.
Liver Transpl
; 16(9): 1075-85, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20818746
2.
Evaluation of BepanGel Hydrogel Efficacy and Tolerability Using an Abrasive Wound Model in a Within-Person, Single-Center, Randomized, Investigator-Blind Clinical Investigation.
Dermatol Ther (Heidelb)
; 10(5): 1075-1088, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-32743789
3.
A DGGE system for comprehensive mutation screening of BRCA1 and BRCA2: application in a Dutch cancer clinic setting.
Hum Mutat
; 27(7): 654-66, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16683254
4.
Low systemic exposure of oral docetaxel in mice resulting from extensive first-pass metabolism is boosted by ritonavir.
Cancer Res
; 62(21): 6158-64, 2002 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12414642
5.
Multidrug resistance protein 2 (MRP2) transports HIV protease inhibitors, and transport can be enhanced by other drugs.
AIDS
; 16(17): 2295-301, 2002 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-12441801
6.
Predicting carrier-mediated hepatic disposition of rosuvastatin in man by scaling from individual transfected cell-lines in vitro using absolute transporter protein quantification and PBPK modeling.
Eur J Pharm Sci
; 65: 156-66, 2014 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25261337
7.
Semi-mechanistic physiologically-based pharmacokinetic modeling of clinical glibenclamide pharmacokinetics and drug-drug-interactions.
Eur J Pharm Sci
; 49(5): 819-28, 2013 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23806476
8.
In vivo visualization and quantification of (Disturbed) Oatp-mediated hepatic uptake and Mrp2-mediated biliary excretion of 99mTc-mebrofenin in mice.
J Nucl Med
; 54(4): 624-30, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23440558
9.
In silico identification of potential cholestasis-inducing agents via modeling of Na(+)-dependent taurocholate cotransporting polypeptide substrate specificity.
Toxicol Sci
; 129(1): 35-48, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22641618
10.
Interaction of fluvastatin with the liver-specific Na+ -dependent taurocholate cotransporting polypeptide (NTCP).
Eur J Pharm Sci
; 44(4): 487-96, 2011 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21945488
11.
MRP2 (ABCC2) transports taxanes and confers paclitaxel resistance and both processes are stimulated by probenecid.
Int J Cancer
; 116(5): 824-9, 2005 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-15849751
12.
Assessing safety and efficacy of directed P-glycoprotein inhibition to improve the pharmacokinetic properties of saquinavir coadministered with ritonavir.
J Pharmacol Exp Ther
; 304(2): 596-602, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12538811
13.
Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2).
J Biol Chem
; 278(26): 23538-44, 2003 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-12702717