Detalhe da pesquisa
1.
Respiratory syncytial virus-A dynamics and the effects of lumicitabine, a nucleoside viral replication inhibitor, in experimentally infected humans.
J Antimicrob Chemother
; 74(2): 442-452, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30376079
2.
A Generic Multi-Compartmental CNS Distribution Model Structure for 9 Drugs Allows Prediction of Human Brain Target Site Concentrations.
Pharm Res
; 34(2): 333-351, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27864744
3.
Prediction of human CNS pharmacokinetics using a physiologically-based pharmacokinetic modeling approach.
Eur J Pharm Sci
; 112: 168-179, 2018 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29133240
4.
Population Pharmacokinetic Modeling of JNJ-53718678, a Novel Fusion Inhibitor for the Treatment of Respiratory Syncytial Virus: Results from a Phase I, Double-Blind, Randomized, Placebo-Controlled First-in-Human Study in Healthy Adult Subjects.
Clin Pharmacokinet
; 56(11): 1331-1342, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28238203
5.
Modeling of prolactin response following dopamine D2 receptor antagonists in rats: can it be translated to clinical dosing?
Pharmacol Res Perspect
; 5(6)2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29226628
6.
Predicting Drug Concentration-Time Profiles in Multiple CNS Compartments Using a Comprehensive Physiologically-Based Pharmacokinetic Model.
CPT Pharmacometrics Syst Pharmacol
; 6(11): 765-777, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28891201
7.
Correlation between in vitro and in vivo concentration-effect relationships of naproxen in rats and healthy volunteers.
Br J Pharmacol
; 148(4): 396-404, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16682968
8.
Population Pharmacokinetic Modeling of Tapentadol Extended Release (ER) in Healthy Subjects and Patients with Moderate or Severe Chronic Pain.
Clin Drug Investig
; 36(3): 213-23, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26798023
9.
A comparison of two semi-mechanistic models for prolactin release and prediction of receptor occupancy following administration of dopamine D2 receptor antagonists in rats.
Eur J Pharmacol
; 789: 202-214, 2016 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27395799
10.
Summary data of potency and parameter information from semi-mechanistic PKPD modeling of prolactin release following administration of the dopamine D2 receptor antagonists risperidone, paliperidone and remoxipride in rats.
Data Brief
; 8: 1433-7, 2016 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-27617278
11.
Impact of chronic inflammation on the pharmacokinetic-pharmacodynamic relationship of naproxen.
Eur J Pain
; 14(3): 227.e1-10, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19679500
12.
Differences in the sensitivity of behavioural measures of pain to the selectivity of cyclo-oxygenase inhibitors.
Eur J Pain
; 13(5): 448-57, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18774319