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1.
J Surg Orthop Adv ; 28(1): 58-62, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31074739

RESUMO

The purpose of this study was to evaluate a multimodal pain management program incorporating periarticular injections of liposomal bupivacaine after hemiarthroplasty treatment of femoral neck fractures. This retrospective study selected patients treated with periarticular injections of liposomal bupivacaine within the multimodal pain management program (LBUP) (n = 100) and a control group of patients treated without local infiltration (n = 78). Similar pain control was achieved between both groups from day 1 to day 4 postsurgery (min p = .392). Length of stay was significantly lower for LBUP patients (4.8 days vs. 5.7 days, p = .013), and LBUP patients were significantly more likely to be ambulatory at discharge (82% vs. 69%, p = .013). LBUP patients were also less likely to need the intensive care unit (4% vs. 14%, p = .027). The percentage of patients with at least one opioid-related adverse event was lower in the LBUP group (3% vs. 8%, p = .156) as was the 90-day mortality rate (2% vs. 8%, p = .069), but the differences were not statistically significant. (Journal of Surgical Orthopaedic Advances 28(1):58-62, 2019).


Assuntos
Artroplastia do Joelho , Fraturas do Colo Femoral , Hemiartroplastia , Manejo da Dor , Fraturas do Colo Femoral/complicações , Fraturas do Colo Femoral/cirurgia , Humanos , Lipossomos , Medição da Dor , Dor Pós-Operatória , Estudos Retrospectivos
2.
N Engl J Med ; 378(10): 972, 2018 03 08.
Artigo em Inglês | MEDLINE | ID: mdl-29514024
3.
J Shoulder Elbow Surg ; 17(2): 342-6, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-17931901

RESUMO

Knowledge of the exact location of the distal biceps brachii insertion is crucial when performing tendon reconstruction or repair. To quantitatively describe the morphology of the distal biceps brachii insertion, 20 cadaveric arms were examined. Linear and angular measurements, including the footprint dimensions and shape, radial tuberosity dimensions and irregularities, and the rotational position of the tuberosity and footprint, were obtained. The axial and transverse dimensions of the radial tuberosity and distal biceps tendon footprint measured 24.2 x 12 mm and 18.7 x 3.7 mm, respectively. The insertion footprint is on the posterior/ulnar aspect of the radial tuberosity centered at approximately 30 degrees anterior to the lateral/coronal plane with the forearm fully supinated. This explains why any preoperative limitation in supination may make an anatomic repair difficult through a single anterior incision. To our knowledge, this is the first study to quantitatively describe the angular location of the radial tuberosity and the relationship of the distal biceps tendon on the tuberosity.


Assuntos
Músculo Esquelético/anatomia & histologia , Rádio (Anatomia)/anatomia & histologia , Tendões/anatomia & histologia , Idoso , Idoso de 80 Anos ou mais , Braço , Cadáver , Humanos , Pessoa de Meia-Idade
4.
J Orthop Trauma ; 32 Suppl 2: S1-S4, 2018 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-30028757

RESUMO

BACKGROUND: Liposomal bupivacaine (LB) has demonstrated efficacy across a range of surgical settings, including shoulder, knee, and hip surgery. However, data are limited on the use of LB as part of a multimodal pain management approach in hip fracture surgery. METHODS: On April 1, 2017, 4 orthopaedic surgeons and 3 anesthesiologists convened to discuss current practices and develop a consensus statement related to local infiltration analgesia with LB for hip fracture surgical procedures within the context of a multimodal opioid-sparing pain management approach. Separate workshops addressed intracapsular and extracapsular hip fracture surgery. RESULTS: Multimodal strategies before, during, and after hip fracture surgery are paramount to optimizing pain control and minimizing opioid requirements. LB infiltration should occur intraoperatively near the time of closing the incision. For both intracapsular and extracapsular procedures, oral or intravenous acetaminophen, a nonsteroidal anti-inflammatory drug (NSAID) of choice, and tramadol should be given preoperatively. Presurgical fascia iliaca block with bupivacaine HCl may help bridge the period before LB takes effect. After both procedures, patients should receive 1 dose of intravenous acetaminophen, an NSAID, and opioid rescue medication as needed, starting with tramadol. Postoperative NSAIDs may help minimize opioid use. Patient and provider education are integral to managing patient expectations and alleviating concerns about pain and opioid use. Standardized, validated, and appropriately timed pain assessments are also necessary to optimize postsurgical pain management. CONCLUSIONS: These consensus recommendations regarding multimodal pain management protocols incorporating local infiltration analgesia with LB for extracapsular and intracapsular hip fracture procedures serve as a basis for additional research. LEVEL OF EVIDENCE: Level V.


Assuntos
Anestésicos Locais/administração & dosagem , Bupivacaína/administração & dosagem , Fraturas do Quadril/cirurgia , Manejo da Dor , Dor Pós-Operatória/tratamento farmacológico , Humanos , Cápsula Articular , Lipossomos , Dor Pós-Operatória/diagnóstico , Dor Pós-Operatória/etiologia , Padrões de Prática Médica
5.
J Orthop Trauma ; 32 Suppl 2: S5-S10, 2018 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-30028758

RESUMO

BACKGROUND: Liposomal bupivacaine (LB) has demonstrated efficacy in improving pain scores and reducing opioid consumption across a variety of surgical settings, including orthopaedic surgery. However, meticulous infiltration techniques combined with a multimodal approach are important to optimizing outcomes. METHODS: A panel of 4 orthopaedic surgeons and 3 anesthesiologists convened on April 1, 2017, to discuss current practices and develop a consensus statement regarding local infiltration analgesia with LB for extracapsular and intracapsular hip fracture surgery, including LB infiltration techniques. RESULTS: Optimizing surgical outcomes with LB in hip fracture surgery requires an understanding of the neuroanatomy of the surgical site and the pharmacology of the drug. Meticulous infiltration technique is critical to achieve optimal results with LB given its viscosity and reduced diffusion compared with bupivacaine HCl. For extracapsular procedures, a total injection volume of 120 mL is recommended, whereas intracapsular procedures typically require a lower volume (∼80 mL). In both cases, infiltration is best achieved using a 22-gauge needle and applying a tracking and/or fanning technique. To ensure optimal placement, LB should be infiltrated using multiple, small-volume (1- to 5-mL) injections spaced at 1.0-cm intervals. CONCLUSIONS: These consensus recommendations regarding LB infiltration techniques can serve as a resource for designing clinical studies to evaluate outcomes using periarticular infiltration of LB in extracapsular and intracapsular hip fracture surgery as part of a multimodal pain management approach. LEVEL OF EVIDENCE: Level V.


Assuntos
Anestesia Local , Anestésicos Locais/administração & dosagem , Bupivacaína/administração & dosagem , Fraturas do Quadril/cirurgia , Manejo da Dor , Dor Pós-Operatória/tratamento farmacológico , Humanos , Cápsula Articular , Lipossomos , Dor Pós-Operatória/diagnóstico , Dor Pós-Operatória/etiologia , Padrões de Prática Médica
6.
Am J Orthop (Belle Mead NJ) ; 43(10 Suppl): S13-6, 2014 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-25303455

RESUMO

Orthopedic trauma surgery is often associated with considerable postoperative pain, which can result in a cascade of direct and indirect clinical consequences. Patients undergoing orthopedic trauma surgery are at risk for the development of chronic postsurgical pain, which may persist for 2 years or longer. Effective approaches to reducing postoperative pain in orthopedic trauma surgery patients include the use of minimally invasive procedures and multimodal analgesia. Infiltration of the surgical site with EXPAREL® (bupivacaine liposome injectable suspension), an extended-release local anesthetic, represents an advance in the multimodal management of postoperative pain. As part of a multimodal regimen, EXPAREL® has been shown to provide effective, safe, and efficient analgesia across a range of surgical procedures. Two cases that illustrate the use of EXPAREL® in orthopedic trauma are described. The first case involves repair of a subtrochanteric nonunion in a 63-year-old woman with a history of bisphosphonate use and prior treatment with a cephalomedullary nail. The second case involves a young woman undergoing outpatient surgery for repair of a fractured clavicle. Both patients experienced good control of postsurgical pain, supporting the clinical utility of EXPAREL® in orthopedic trauma surgery.


Assuntos
Bupivacaína/administração & dosagem , Fixação Interna de Fraturas , Manejo da Dor/métodos , Dor Pós-Operatória/tratamento farmacológico , Adulto , Anestésicos Locais/administração & dosagem , Clavícula/lesões , Feminino , Fraturas do Fêmur/cirurgia , Humanos , Lipossomos , Pessoa de Meia-Idade , Medição da Dor , Dor Pós-Operatória/diagnóstico
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