Detalhe da pesquisa
1.
Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality.
Proc Natl Acad Sci U S A
; 112(44): 13573-8, 2015 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26487682
2.
Deleting titin's I-band/A-band junction reveals critical roles for titin in biomechanical sensing and cardiac function.
Proc Natl Acad Sci U S A
; 111(40): 14589-94, 2014 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25246556
3.
Increased myocardial stiffness due to cardiac titin isoform switching in a mouse model of volume overload limits eccentric remodeling.
J Mol Cell Cardiol
; 79: 104-14, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25450617
4.
Experimentally increasing titin compliance in a novel mouse model attenuates the Frank-Starling mechanism but has a beneficial effect on diastole.
Circulation
; 129(19): 1924-36, 2014 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24599837
5.
Shortening of the elastic tandem immunoglobulin segment of titin leads to diastolic dysfunction.
Circulation
; 128(1): 19-28, 2013 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23709671
6.
The multifunctional Ca(2+)/calmodulin-dependent protein kinase II delta (CaMKIIδ) phosphorylates cardiac titin's spring elements.
J Mol Cell Cardiol
; 54: 90-7, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23220127
7.
In vivo and in vitro cardiac responses to beta-adrenergic stimulation in volume-overload heart failure.
J Mol Cell Cardiol
; 57: 47-58, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23220155
8.
Early heart failure in the SMNDelta7 model of spinal muscular atrophy and correction by postnatal scAAV9-SMN delivery.
Hum Mol Genet
; 19(20): 3895-905, 2010 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20639395
9.
Coronary arterioles in type 2 diabetic (db/db) mice undergo a distinct pattern of remodeling associated with decreased vessel stiffness.
Basic Res Cardiol
; 106(6): 1123-34, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21744279
10.
Extracellular matrix remodeling during the progression of volume overload-induced heart failure.
J Mol Cell Cardiol
; 48(3): 564-9, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19524591
11.
Cardiac fibroblast-dependent extracellular matrix accumulation is associated with diastolic stiffness in type 2 diabetes.
PLoS One
; 8(8): e72080, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23991045
12.
Cardiovascular remodeling in response to long-term exposure to fine particulate matter air pollution.
Circ Heart Fail
; 5(4): 452-61, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22661498
13.
Myocardial dysfunction in an animal model of cancer cachexia.
Life Sci
; 88(9-10): 406-10, 2011 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21167183
14.
Systemic maternal inflammation and neonatal hyperoxia induces remodeling and left ventricular dysfunction in mice.
PLoS One
; 6(9): e24544, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21935422
15.
Temporal pattern of left ventricular structural and functional remodeling following reversal of volume overload heart failure.
J Appl Physiol (1985)
; 111(6): 1778-88, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21885799