Detalhe da pesquisa
1.
Regulation of autophagosome biogenesis by OFD1-mediated selective autophagy.
EMBO J
; 40(4): e105120, 2021 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33368531
2.
The HOPS complex subunit VPS39 controls ciliogenesis through autophagy.
Hum Mol Genet
; 29(6): 1018-1029, 2020 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32077937
3.
Development of a novel SNP assay to detect lactase persistence associated genetic variants.
Mol Biol Rep
; 48(11): 7087-7093, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34515921
4.
Oral-facial-digital syndrome type I cells exhibit impaired DNA repair; unanticipated consequences of defective OFD1 outside of the cilia network.
Hum Mol Genet
; 26(1): 19-32, 2017 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27798113
5.
Mutations in COX7B cause microphthalmia with linear skin lesions, an unconventional mitochondrial disease.
Am J Hum Genet
; 91(5): 942-9, 2012 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23122588
6.
Drug repurposing screen to identify inhibitors of the RNA polymerase (nsp12) and helicase (nsp13) from SARS-CoV-2 replication and transcription complex.
Virus Res
; 343: 199356, 2024 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38490582
7.
ProfhEX: AI-based platform for small molecules liability profiling.
J Cheminform
; 15(1): 60, 2023 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37296454
8.
Diketo acid inhibitors of nsp13 of SARS-CoV-2 block viral replication.
Antiviral Res
; 217: 105697, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37562607
9.
DHFR Inhibitors Display a Pleiotropic Anti-Viral Activity against SARS-CoV-2: Insights into the Mechanisms of Action.
Viruses
; 15(5)2023 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37243214
10.
Kidney-specific inactivation of Ofd1 leads to renal cystic disease associated with upregulation of the mTOR pathway.
Hum Mol Genet
; 19(14): 2792-803, 2010 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20444807
11.
Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities.
ACS Pharmacol Transl Sci
; 5(4): 226-239, 2022 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35434533
12.
Paclitaxel binds and activates C5aR1: A new potential therapeutic target for the prevention of chemotherapy-induced peripheral neuropathy and hypersensitivity reactions.
Cell Death Dis
; 13(5): 500, 2022 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35614037
13.
Characterization of raloxifene as a potential pharmacological agent against SARS-CoV-2 and its variants.
Cell Death Dis
; 13(5): 498, 2022 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35614039
14.
Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort.
Sci Data
; 9(1): 405, 2022 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35831315
15.
The SARS-CoV-2 spike protein binds and modulates estrogen receptors.
bioRxiv
; 2022 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35665018
16.
The SARS-CoV-2 spike protein binds and modulates estrogen receptors.
Sci Adv
; 8(48): eadd4150, 2022 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36449624
17.
S-Carboxymethyl Cysteine Protects against Oxidative Stress and Mitochondrial Impairment in a Parkinson's Disease In Vitro Model.
Biomedicines
; 9(10)2021 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34680584
18.
L-Methionine Protects against Oxidative Stress and Mitochondrial Dysfunction in an In Vitro Model of Parkinson's Disease.
Antioxidants (Basel)
; 10(9)2021 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34573099
19.
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen.
ACS Pharmacol Transl Sci
; 4(3): 1096-1110, 2021 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35287429
20.
The centrosomal/basal body protein OFD1 is required for microtubule organization and cell cycle progression.
Tissue Cell
; 64: 101369, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-32473706