Editorial to the Special Issue Optical Fiber Sensors in Radiation Environments.

Optical fibers are well known for their use in high-speed data links and related sensors nowadays find application in different domains, such as structural health monitoring, distributed sensing, but also biological and chemical monitoring [...].

Innovative Photonic Sensors for Safety and Security, Part II: Aerospace and Submarine Applications.

The employability of photonics technology in the modern era's highly demanding and sophisticated domain of aerospace and submarines has been an appealing challenge for the scientific communities. In this paper, we review our main results achieved so far on the use of optical fiber sensors for safety and security in innovative aerospace and submarine applications. In particular, recent results of in-field applications of optical fiber sensors in aircraft monitoring, from a weight and balance analysis to vehicle Structural Health Monitoring (SHM) and Landing Gear (LG) monitoring, are presented and discussed. Moreover, underwater fiber-optic hydrophones are presented from the design to marine application.

Innovative Photonic Sensors for Safety and Security, Part I: Fundamentals, Infrastructural and Ground Transportations.

Our group, involving researchers from different universities in Campania, Italy, has been working for the last twenty years in the field of photonic sensors for safety and security in healthcare, industrial and environment applications. This is the first in a series of three companion papers. In this paper, we introduce the main concepts of the technologies employed for the realization of our photonic sensors. Then, we review our main results concerning the innovative applications for infrastructural and transportation monitoring.

Innovative Photonic Sensors for Safety and Security, Part III: Environment, Agriculture and Soil Monitoring.

In order to complete this set of three companion papers, in this last, we focus our attention on environmental monitoring by taking advantage of photonic technologies. After reporting on some configurations useful for high precision agriculture, we explore the problems connected with soil water content measurement and landslide early warning. Then, we concentrate on a new generation of seismic sensors useful in both terrestrial and under water contests. Finally, we discuss a number of optical fiber sensors for use in radiation environments.

Radiation Effects on Long Period Fiber Gratings: A Review.

Over the last years, fiber optic sensors have been increasingly applied for applications in environments with a high level of radiation as an alternative to electrical sensors, due to their: high immunity, high multiplexing and long-distance monitoring capability. In order to assess the feasibility of their use, investigations on optical materials and fiber optic sensors have been focusing on their response depending on radiation type, absorbed dose, dose rate, temperature and so on. In this context, this paper presents a comprehensive review of the results achieved over the last twenty years concerning the irradiation of in-fiber Long Period Gratings (LPGs). The topic is approached from the point of view of the optical engineers engaged in the design, development and testing of these devices, by focusing the attention on the fiber type, grating fabrication technique and properties, irradiation parameters and performed analysis. The aim is to provide a detailed review concerning the state of the art and to outline the future research trends.

A New Setup for Real-Time Investigations of Optical Fiber Sensors Subjected to Gamma-Rays: Case Study on Long Period Gratings.

In this work, we present a new setup for real-time investigations of optical fibers and optical fiber sensors while being subjected to gamma-rays. The investigation of the radiation effects on novel or well-assessed sensing devices has attracted a lot of interest, however, the facilities required to do this (when available) are barely accessible to the device to be characterized. In order to reduce the limitations of these types of experiments and ensure a highly controlled environment, we implemented a configuration that permits the on-line testing of optical components inside a Co-60 gamma chamber research irradiator. To show the advantages of this new approach, we present a case study that compares an arc-induced optical fiber long period grating (LPG) irradiated in a gamma chamber with the same type of grating irradiated with gamma-rays from a Co-60 industrial irradiator. In order to better understand the effects of radiation on such components and their behavior in radiation environments, we focus on the homogeneity of the radiation field and parameter customizability as well as the high reproducibility of the experiments.

Multipoint Temperature Monitoring of Microwave Thermal Ablation in Bones through Fiber Bragg Grating Sensor Arrays.

Bones are a frequent site of metastases that cause intolerable cancer-related pain in 90% of patients, making their quality of life poor. In this scenario, being able to treat bone oncology patients by means of minimally invasive techniques can be crucial to avoid surgery-related risks and decrease hospitalization times. The use of microwave ablation (MWA) is gaining broad clinical acceptance to treat bone tumors. It is worth investigating temperature variations in bone tissue undergoing MWA because the clinical outcomes can be inferred from this parameter. Several feasibility studies have been performed, but an experimental analysis of the temperature trends reached into the bone during the MWA has not yet been assessed. In this work, a multi-point temperature study along the bone structure during such treatment is presented. The study has been carried out on ex vivo bovine femur and tibia, subjected to MWA. An overall of 40 measurement points covering a large sensing area was obtained for each configuration. Temperature monitoring was performed by using 40 fiber Bragg grating (FBGs) sensors (four arrays each housing 10 FBGs), inserted into the bones at specific distances to the microwave antenna. As result, the ability of this experimental multi-point monitoring approach in tracking temperature variations within bone tissue during MWA treatments was shown. This study lays the foundations for the design of a novel approach to study the effects of MWA on bone tumors. As consequence, the MWA treatment settings could be optimized in order to maximize the treatment effects of such a promising clinical application, but also customized for the specific tumor and patient.

Strain Monitoring of a Composite Drag Strut in Aircraft Landing Gear by Fiber Bragg Grating Sensors.

This work reports on the use of Fiber Bragg Grating (FBG) sensors integrated with innovative composite items of aircraft landing gear for strain/stress monitoring. Recently, the introduction of innovative structures in aeronautical applications is appealing with two main goals: (i) to decrease the weight and cost of current items; and (ii) to increase the mechanical resistance, if possible. However, the introduction of novel structures in the aeronautical field demands experimentation and certification regarding their mechanical resistance. In this work, we successfully investigate the possibility to use Fiber Bragg Grating sensors for the structural health monitoring of innovative composite items for the landing gear. Several FBG strain sensors have been integrated in different locations of the composite item including region with high bending radius. To optimize the localization of the FBG sensors, load condition was studied by Finite Element Method (FEM) numerical analysis. Several experimental tests have been done in range 0-70 kN by means of a hydraulic press. Obtained results are in very good agreement with the numerical ones and demonstrate the great potentialities of FBG sensor technology to be employed for remote and real-time load measurements on aircraft landing gears and to act as early warning systems.

Arc-Induced Long Period Gratings from Standard to Polarization-Maintaining and Photonic Crystal Fibers.

In this work, we report about our recent results concerning the fabrication of Long Period Grating (LPG) sensors in several optical fibers, through the Electric Arc Discharge (EAD) technique. In particular, the following silica fibers with both different dopants and geometrical structures are considered: standard Ge-doped, photosensitive B/Ge codoped, P-doped, pure-silica core with F-doped cladding, Panda type Polarization-maintaining, and Hollow core Photonic crystal fiber. An adaptive platform was developed and the appropriate "recipe" was identified for each fiber, in terms of both arc discharge parameters and setup arrangement, for manufacturing LPGs with strong and narrow attenuation bands, low insertion losses, and short length. As the fabricated devices have appealing features from the application point of view, the sensitivity characteristics towards changes in different external perturbations (i.e., surrounding refractive index, temperature, and strain) are investigated and compared, highlighting the effects of different fiber composition and structure.

Liquefied Petroleum Gas Monitoring System Based on Polystyrene Coated Long Period Grating.

In this work, we report the in-field demonstration of a liquefied petroleum gas monitoring system based on optical fiber technology. Long-period grating coated with a thin layer of atactic polystyrene (aPS) was employed as a gas sensor, and an array comprising two different fiber Bragg gratings was set for the monitoring of environmental conditions such as temperature and humidity. A custom package was developed for the sensors, ensuring their suitable installation and operation in harsh conditions. The developed system was installed in a real railway location scenario (i.e., a southern Italian operative railway tunnel), and tests were performed to validate the system performances in operational mode. Daytime normal working operations of the railway line and controlled gas expositions, at very low concentrations, were the searched realistic conditions for an out-of-lab validation of the developed system. Encouraging results were obtained with a precise indication of the gas concentration and external conditioning of the sensor.

Sensing features of long period gratings in hollow core fibers.

We report on the investigation of the sensing features of the Long-Period fiber Gratings (LPGs) fabricated in hollow core photonic crystal fibers (HC-PCFs) by the pressure assisted Electric Arc Discharge (EAD) technique. In particular, the characterization of the LPG in terms of shift in resonant wavelengths and changes in attenuation band depth to the environmental parameters: strain, temperature, curvature, refractive index and pressure is presented. The achieved results show that LPGs in HC-PCFs represent a novel high performance sensing platform for measurements of different physical parameters including strain, temperature and, especially, for measurements of environmental pressure. The pressure sensitivity enhancement is about four times greater if we compare LPGs in HC and standard fibers. Moreover, differently from LPGs in standard fibers, these LPGs realized in innovative fibers, i.e., the HC-PCFs, are not sensitive to surrounding refractive index.

Introduction to the feature issue: Advances in Optical Biosensors for Biomedical Applications.

The feature issue of Biomedical Optics Express titled "Advances in Optical Biosensors for Biomedical Applications" presents a comprehensive collection of cutting-edge optical biosensor research. With the growing demand for sensitive, label-free, and real-time detection of biological analytes, optical biosensors have emerged as important devices in a wide range of biomedical applications, including medical diagnostics, bioanalysis, and personalised healthcare. This collection of 26 papers highlights recent advances and innovations in the development, design, and implementation of optical biosensors. The feature issue serves as an opportunity for disseminating ground-breaking findings, promoting new ideas, and inspiring further developments in optical biosensors for medical applications. The authors provide breakthrough technology, innovative approaches, and practical clinical applications that have the potential to revolutionize healthcare and biomedical research.

A review on radiofrequency, laser, and microwave ablations and their thermal monitoring through fiber Bragg gratings.

Thermal ablation of tumors aims to apply extreme temperatures inside the target tissue to achieve substantial tumor destruction in a minimally invasive manner. Several techniques are comprised, classified according to the type of energy source. However, the lack of treatment selectivity still needs to be addressed, potentially causing two risks: i) incomplete tumor destruction and recurrence, or conversely, ii) damage of the surrounding healthy tissue. Therefore, the research herein reviewed seeks to develop sensing systems based on fiber Bragg gratings (FBGs) for thermal monitoring inside the lesion during radiofrequency, laser, and microwave ablation. This review shows that, mainly thanks to multiplexing and minimal invasiveness, FBGs provide an optimal sensing solution. Their temperature measurements are the feedback to control the ablation process and allow to investigate different treatments, compare their outcomes, and quantify the impact of factors such as proximity to thermal probe and blood vessels, perfusion, and tissue type.

Long period grating in double cladding fiber coated with graphene oxide as high-performance optical platform for biosensing.

In this work, the development and testing of a novel fiber-optic based label-free biosensor is presented, whose performance were verified through the detection of C-reactive protein (CRP) in serum. The device is based on a long period grating fabricated in a double cladding fiber with a W-shaped refractive index (RI) profile. As a result, the working point of the device was tuned to the mode transition region by chemical etching of the outer fiber cladding, obtaining a significant enhancement of the RI sensitivity and an excellent visibility of the grating resonances due to the mode transition in an all-silica structure. The fiber transducer was coated with a nanometric thin layer of graphene oxide in order to provide functional groups for the covalent immobilization of the biological recognition element. A very low limit of detection of about 0.15 ng/mL was obtained during the detection of CRP in serum, and a large working range (1 ng/mL - 100 µg/mL) of clinical relevance has been also achieved.

Fiber Optic Sensors-Based Thermal Analysis of Perfusion-Mediated Tissue Cooling in Liver Undergoing Laser Ablation.

The current challenge in the field of thermo-ablative treatments of tumors is to achieve a balance between complete destruction of malignant cells and safeguarding of the surrounding healthy tissue. Blood perfusion plays a key role for thermal ablation success, especially in the case of highly vascularized organs like liver. This work aims at monitoring the temperature within perfused swine liver undergoing laser ablation (LA). Temperature was measured through seven arrays of Fiber Bragg Grating sensors (FBGs) around the laser applicator. To mimic reality, blood perfusion within the ex-vivo liver was simulated using artificial vessels. The influence of blood perfusion on LA was carried out by comparing the temperature profiles in two different spatial configurations of vessels and fibers. The proposed setup permitted to accurately measure the heat propagation in real-time with a temperature resolution of 0.1 °C and to observe a relevant tissue cooling near to the vessel up to 65%.

Not-lithographic fabrication of micro-structured fiber Bragg gratings evanescent wave sensors.

This work is devoted to present and to demonstrate a novel approach for the fabrication of micro-structured fiber Bragg gratings (MSFBGs) to be employed as technological platform for advanced optochemical sensors. Basically, the MSFBG consists in a localized SRI sensitization of the grating by deep cladding stripping. The introduction of a perturbation or defect along the grating leads to the formation of a defect state inside the FBG spectral response that is tunable through the surrounding medium refractive index. While its spectral features for sensing and communication applications have been widely described and commented elsewhere, here a simple fabrication procedure is presented as suitable technological assessment enabling cost effective and simple MSFBG production. It relies on a two steps technique based on arc-discharge procedure as fiber pre-treatment and mask-less wet chemical etching to locally sensitize the FBG to external refractive index. The new, simple and low-cost approach overcomes some technological drawbacks related to previous fabrication techniques adopting patterned masking procedures during the etching process. This work demonstrates the effectiveness of the proposed method reporting a detailed description of single and two defects MSFBG fabrication.

Photonic band-gap engineering in UV fiber gratings by the arc discharge technique.

Localized heat treatments combined with local non-adiabatic tapering is proposed as suitable tool for the engineering of photonic band-gaps in UV-written fiber Bragg gratings (FBGs). In particular, here, we propose the use of the electric arc discharge to achieve localized defects along the FBG structure, however differently from previously reported works, we demonstrate how this post processing tool properly modified can be exploited to achieve the full control of the spectral characteristics of the final device. Also, we show how the suitable choice of the grating features and the correct selection of the defect geometry can be efficiently used to achieve interesting features for both communication and sensing applications.

Multidimensional thermal mapping during radiofrequency ablation treatments with minimally invasive fiber optic sensors.

Temperature mapping is a key asset in supporting the clinician during thermal ablation (TA) treatment of tumors without adding additional risk to the TA procedure. Herein we report our experiments on multidimensional thermal mapping during radio frequency (RF) thermal ablation treatments of an ex-vivo animal organ. The temperature was monitored using several arrays of fiber Bragg gratings properly positioned around the RF applicator. The results show the effectiveness of our proposed method at assessing the TA probe depth and demonstrating how the insertion depth directly influences the maximum temperature and the treated area of the radio frequency ablation.

Real-time analysis of arc-induced Long Period Gratings under gamma irradiation.

In this paper, we present a comparative experimental and theoretical study on gamma radiation sensitivity of Long Period Gratings (LPGs), fabricated by electric arc discharge technique, as monitored in three single mode optical fibers supplied by different manufacturers. A real-time measurement of LPGs' wavelength shift was performed until a total dose of 35 kGy was reached, with average dose rate of 0.18 kGy/h, the irradiation being done at room temperature. In one case, a maximum radiation sensitivity of 1.34 nm/kGy was recorded for doses up to 0.5 kGy. Moreover, by combining experimental results with numerical simulations, it was found that changes occurred in the core refractive index of the irradiated optical fibers up to 2.5 ∙ 10-5. The increase of the core thermo-optic coefficient up to 1.5 ∙ 10-8/°C was observed as well.

Arc-induced Long Period Gratings in standard and speciality optical fibers under mixed neutron-gamma irradiation.

In this paper, for the first time, the effects of mixed neutron and gamma flux on the spectral and sensing responses of Long Period Gratings (LPGs) are thoroughly analyzed. Six LPGs written by means of Electric Arc Discharge (EAD) technique in standard and speciality fibers, including radiation-hardened ones, were tested. The EAD technique was chosen because it enables the writing of gratings both in standard and not photosensitive fibers. The experiments have been carried out in a "TRIGA" pulsed nuclear reactor and the LPGs were irradiated by a gamma-ray dose-rate of 9 Gy/s and a mean 1.2∙1012 n/(cm2s) neutron flux. Real time monitoring was performed for a comparative investigation of LPGs' response, in terms of radiation sensitivity and wavelength shift. Experiments show that LPG in a radiation-resistant fiber exhibits resonant wavelength shift higher than LPG in standard fiber. The changes of temperature sensitivity due to radiation were experimentally established by comparison of pre- and post-radiation characterization, indicating that radiation effects induce a slight increase of the temperature sensitivity, except for the LPG in pure-silica fiber. Theoretical and numerical analysis was combined with experimental data for evaluation LPGs' parameters changes, such as refractive index and thermo-optic coefficient, after exposure to radiation.