Detalhe da pesquisa
1.
The small molecule activator S3969 stimulates the epithelial sodium channel by interacting with a specific binding pocket in the channel's ß-subunit.
J Biol Chem
; 300(4): 105785, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38401845
2.
Transmembrane serine protease 2 (TMPRSS2) proteolytically activates the epithelial sodium channel (ENaC) by cleaving the channel's γ-subunit.
J Biol Chem
; 298(6): 102004, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35504352
3.
A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts.
J Cell Sci
; 134(16)2021 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34345895
4.
Inhibition of the epithelial sodium channel (ENaC) by connexin 30 involves stimulation of clathrin-mediated endocytosis.
J Biol Chem
; 296: 100404, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33577799
5.
Proteolytic activation of the epithelial sodium channel (ENaC) by factor VII activating protease (FSAP) and its relevance for sodium retention in nephrotic mice.
Pflugers Arch
; 474(2): 217-229, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34870751
6.
Contributions of bile acids to gastrointestinal physiology as receptor agonists and modifiers of ion channels.
Am J Physiol Gastrointest Liver Physiol
; 322(2): G201-G222, 2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34755536
7.
The degenerin region of the human bile acid-sensitive ion channel (BASIC) is involved in channel inhibition by calcium and activation by bile acids.
Pflugers Arch
; 470(7): 1087-1102, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29589117
8.
Activation of the Human Epithelial Sodium Channel (ENaC) by Bile Acids Involves the Degenerin Site.
J Biol Chem
; 291(38): 19835-47, 2016 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27489102
9.
Zymogen-locked mutant prostasin (Prss8) leads to incomplete proteolytic activation of the epithelial sodium channel (ENaC) and severely compromises triamterene tolerance in mice.
Acta Physiol (Oxf)
; 232(1): e13640, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33650216
10.
Bile acids inhibit human purinergic receptor P2X4 in a heterologous expression system.
J Gen Physiol
; 151(6): 820-833, 2019 06 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30988062
11.
Urokinase-type plasminogen activator (uPA) is not essential for epithelial sodium channel (ENaC)-mediated sodium retention in experimental nephrotic syndrome.
Acta Physiol (Oxf)
; 227(4): e13286, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31006168
12.
Bile acids potentiate proton-activated currents in Xenopus laevis oocytes expressing human acid-sensing ion channel (ASIC1a).
Physiol Rep
; 5(3)2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-28193786