Detalhe da pesquisa
1.
Insights into the pathological basis of dementia from population-based neuropathology studies.
Neuropathol Appl Neurobiol
; 49(4): e12923, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37462105
2.
Neutrophil-Derived Microvesicle Induced Dysfunction of Brain Microvascular Endothelial Cells In Vitro.
Int J Mol Sci
; 20(20)2019 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31652502
3.
Metallothionein-I/II expression associates with the astrocyte DNA damage response and not Alzheimer-type pathology in the aging brain.
Glia
; 66(11): 2316-2323, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30098078
4.
Local volume fraction distributions of axons, astrocytes, and myelin in deep subcortical white matter.
Neuroimage
; 179: 275-287, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29933040
5.
Proteomic and cellular localisation studies suggest non-tight junction cytoplasmic and nuclear roles for occludin in astrocytes.
Eur J Neurosci
; 47(12): 1444-1456, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29738614
6.
Microglial immunophenotype in dementia with Alzheimer's pathology.
J Neuroinflammation
; 13(1): 135, 2016 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27256292
7.
Motor neurone disease/amyotrophic lateral sclerosis associated with intermediate-length CAG repeat expansions in Ataxin-2 does not have 1C2-positive polyglutamine inclusions.
Neuropathol Appl Neurobiol
; 42(4): 377-89, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26095883
8.
Neuronal DNA damage response-associated dysregulation of signalling pathways and cholesterol metabolism at the earliest stages of Alzheimer-type pathology.
Neuropathol Appl Neurobiol
; 42(2): 167-79, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26095650
9.
Oligogenic inheritance of optineurin (OPTN) and C9ORF72 mutations in ALS highlights localisation of OPTN in the TDP-43-negative inclusions of C9ORF72-ALS.
Neuropathology
; 36(2): 125-34, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26303227
10.
A neuronal DNA damage response is detected at the earliest stages of Alzheimer's neuropathology and correlates with cognitive impairment in the Medical Research Council's Cognitive Function and Ageing Study ageing brain cohort.
Neuropathol Appl Neurobiol
; 41(4): 483-96, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25443110
11.
Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy.
Acta Neuropathol
; 130(1): 63-75, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25943887
12.
Neuropathological assessments of the pathology in frontotemporal lobar degeneration with TDP43-positive inclusions: an inter-laboratory study by the BrainNet Europe consortium.
J Neural Transm (Vienna)
; 122(7): 957-72, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25239189
13.
Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions.
Brain
; 137(Pt 7): 2040-51, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24866055
14.
DNA damage response and senescence in endothelial cells of human cerebral cortex and relation to Alzheimer's neuropathology progression: a population-based study in the Medical Research Council Cognitive Function and Ageing Study (MRC-CFAS) cohort.
Neuropathol Appl Neurobiol
; 40(7): 802-14, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24861546
15.
Loss of nuclear TDP-43 in amyotrophic lateral sclerosis (ALS) causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurones.
Neuropathol Appl Neurobiol
; 40(6): 670-85, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24750229
16.
TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions.
Acta Neuropathol
; 127(3): 407-18, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24442578
17.
Unravelling the enigma of selective vulnerability in neurodegeneration: motor neurons resistant to degeneration in ALS show distinct gene expression characteristics and decreased susceptibility to excitotoxicity.
Acta Neuropathol
; 125(1): 95-109, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23143228
18.
Sensory neuronopathy in patients harbouring recessive polymerase γ mutations.
Brain
; 135(Pt 1): 62-71, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22189570
19.
Clinico-pathological features in amyotrophic lateral sclerosis with expansions in C9ORF72.
Brain
; 135(Pt 3): 751-64, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22366792
20.
Assessment of Alzheimer-related pathologies of dementia using machine learning feature selection.
Alzheimers Res Ther
; 15(1): 47, 2023 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36895019