TYPE 2 DIABETES MELLITUS PREVALENCE IN PATIENTS WITH CARDIOVASCULAR DIEASES.

OBJECTIVE: The aim: To estimate type 2 diabetes mellitus (T2DM) prevalence in patients who came for a consultation to the private practice cardiologist. PATIENTS AND METHODS: Materials and methods: 97 patients with cardiovascular diseases (СVD), visited a cardiologist in private medical center, were included (mean age 49,5 (42,8; 58,3) years, 43 (44.3 %) males) and T2DM prevalence was estimated. RESULTS: Results: 84 (86.6 %) patients had arterial hypertension, 19 patients (19.6 %) had coronary artery disease. Mean body mass index was 29,4 (25,2; 33,4) kg/m2. Waist circumference above recommended was observed in 78.4 %. 30 рatients (30.9 %) were overweight, 44.3 % had abdominal obesity. Almost all patients had atherogenic dyslipidemia. Total T2DM prevalence was 19.6 %, including cases of first-diagnosed diabetes (17.5 %). CONCLUSION: Conclusions: T2DM and prediabetes prevalence in our sample of patients with CVD was higer than described for the general population. Рatients with cardiovascular diseases require careful assessment of diabetes risk factors for its timely detection and for possiblу improving the outcomes.

Gender differences in clinical factors associated with coronary artery atherosclerosis severity in patients with aortic valve and/or mitral annulus calcification.

OBJECTIVE: Introduction: The previous studies of coronary atherosclerosis association with aortic valve calcification (AVC) and/or mitral annulus calcification (MAC) had contradictory results. The aim: To assess gender differences in clinical factors associated with coronary artery atherosclerosis severity. PATIENTS AND METHODS: Materials and methods: 362 patients (mean age 63.9 (8.8) years, 244 (67.4%) males) who underwent coronary angiography were included in the retrospective study. AVC and/or MAC presence was determined using transthoracic echocardioscopy. Coronary angiography results were assessed using coronary atherosclerosis severity index (CASI). RESULTS: Results: There were lower CASI in aortic stenosis (AS) subgroups (0 (0; 3.5) and (0; 9.5) in subgroups with severe and moderate AS respectively versus 12.0 (6.0; 20.5) in subgroup without AS, <0.005). Man with AVC and/or MAC (without AS and diabetes mellitus (DM)) had higher CASI compared to man without heart valve calcification and without DM (15.0 (7.0; 21.5) versus 7.0 (2.0; 12.0), p=0.0002), whereas in the similar woman subgroups CASI did not differ. In the male group without DM (without AS) CASI was associated with age (r=0.319, <0.0001), glomerular filtration rate (GFR) (r=(-0.164), p=0.049), cholesterol level (r=0.242, p=0.003) and the combined presence of AVC and MAC (r=0.229, p=0.006), whereas in the similar female group there were only CASI association with GFR (r=(-0.252), p=0.050) and with combined presence of AVC and MAC (r=0.219, p=0.080). CONCLUSION: Conclusions: CASI depended on AS severity. In subgroups without AS and DM CASI was associated with combined presence of AVC and MAC, GFR, and besides with age and cholesterol level in man.