Detalhe da pesquisa
1.
The OncoPPi Portal: an integrative resource to explore and prioritize protein-protein interactions for cancer target discovery.
Bioinformatics
; 34(7): 1183-1191, 2018 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29186335
2.
AKT1, LKB1, and YAP1 Revealed as MYC Interactors with NanoLuc-Based Protein-Fragment Complementation Assay.
Mol Pharmacol
; 91(4): 339-347, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28087810
3.
Application of the bridgehead fragments for the design of conformationally restricted melatonin analogues.
Bioorg Chem
; 39(2): 67-72, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21419469
4.
Enhanced potency of nucleotide-dendrimer conjugates as agonists of the P2Y14 receptor: multivalent effect in G protein-coupled receptor recognition.
Bioconjug Chem
; 20(8): 1650-9, 2009 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-19572637
5.
Molecular recognition in the P2Y(14) receptor: Probing the structurally permissive terminal sugar moiety of uridine-5'-diphosphoglucose.
Bioorg Med Chem
; 17(14): 5298-311, 2009 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19502066
6.
Medicinal chemistry of the A3 adenosine receptor: agonists, antagonists, and receptor engineering.
Handb Exp Pharmacol
; (193): 123-59, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19639281
7.
Probing distal regions of the A2B adenosine receptor by quantitative structure-activity relationship modeling of known and novel agonists.
J Med Chem
; 51(7): 2088-99, 2008 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-18321038
8.
Molecular modeling of a PAMAM-CGS21680 dendrimer bound to an A2A adenosine receptor homodimer.
Bioorg Med Chem Lett
; 18(15): 4312-5, 2008 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18639453
9.
Design, synthesis, and bioactivity of putative tubulin ligands with adamantane core.
Bioorg Med Chem Lett
; 18(18): 5091-4, 2008 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18715782
10.
In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer.
Nat Commun
; 9(1): 2732, 2018 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30013058
11.
Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptor.
J Med Chem
; 50(9): 2030-9, 2007 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-17407275
12.
Structure-activity relationships of 2,N(6),5'-substituted adenosine derivatives with potent activity at the A2B adenosine receptor.
J Med Chem
; 50(8): 1810-27, 2007 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-17378544
13.
Molecular modeling of the human P2Y2 receptor and design of a selective agonist, 2'-amino-2'-deoxy-2-thiouridine 5'-triphosphate.
J Med Chem
; 50(6): 1166-76, 2007 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-17302398
14.
Computer aided comparative analysis of the binding modes of the adenosine receptor agonists for all known subtypes of adenosine receptors.
J Mol Graph Model
; 25(5): 740-54, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17095272
15.
MEDICI: Mining Essentiality Data to Identify Critical Interactions for Cancer Drug Target Discovery and Development.
PLoS One
; 12(1): e0170339, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28118365
16.
The OncoPPi network of cancer-focused protein-protein interactions to inform biological insights and therapeutic strategies.
Nat Commun
; 8: 14356, 2017 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28205554
17.
Structure activity and molecular modeling analyses of ribose- and base-modified uridine 5'-triphosphate analogues at the human P2Y2 and P2Y4 receptors.
Biochem Pharmacol
; 71(4): 540-9, 2006 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-16359641
18.
Agonists and antagonists for P2 receptors.
Novartis Found Symp
; 276: 58-68; discussion 68-72, 107-12, 275-81, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16805423
19.
How evolving enzymes can beat the heat and avoid defeat.
Nat Chem Biol
; 5(8): 538-9, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19620993
20.
Enabling systematic interrogation of protein-protein interactions in live cells with a versatile ultra-high-throughput biosensor platform.
J Mol Cell Biol
; 8(3): 271-81, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26578655