Detalhe da pesquisa
1.
Selection-free precise gene repair using high-capacity adenovector delivery of advanced prime editing systems rescues dystrophin synthesis in DMD muscle cells.
Nucleic Acids Res
; 52(5): 2740-2757, 2024 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38321963
2.
Precise homology-directed installation of large genomic edits in human cells with cleaving and nicking high-specificity Cas9 variants.
Nucleic Acids Res
; 51(7): 3465-3484, 2023 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36928106
3.
Large-scale genome editing based on high-capacity adenovectors and CRISPR-Cas9 nucleases rescues full-length dystrophin synthesis in DMD muscle cells.
Nucleic Acids Res
; 50(13): 7761-7782, 2022 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35776127
4.
Broadening the reach and investigating the potential of prime editors through fully viral gene-deleted adenoviral vector delivery.
Nucleic Acids Res
; 49(20): 11986-12001, 2021 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34669958
5.
Precise and broad scope genome editing based on high-specificity Cas9 nickases.
Nucleic Acids Res
; 49(2): 1173-1198, 2021 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33398349
6.
Expanding the editable genome and CRISPR-Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking.
Nucleic Acids Res
; 48(2): 974-995, 2020 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31799604
7.
Integrating gene delivery and gene-editing technologies by adenoviral vector transfer of optimized CRISPR-Cas9 components.
Gene Ther
; 27(5): 209-225, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31900423
8.
Selection-free gene repair after adenoviral vector transduction of designer nucleases: rescue of dystrophin synthesis in DMD muscle cell populations.
Nucleic Acids Res
; 44(3): 1449-70, 2016 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26762977
9.
Probing the impact of chromatin conformation on genome editing tools.
Nucleic Acids Res
; 44(13): 6482-92, 2016 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27280977
10.
Adenoviral vector DNA for accurate genome editing with engineered nucleases.
Nat Methods
; 11(10): 1051-7, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25152084
11.
Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells.
Nucleic Acids Res
; 41(5): e63, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23275534
12.
Development of an AdEasy-based system to produce first- and second-generation adenoviral vectors with tropism for CAR- or CD46-positive cells.
J Gene Med
; 15(1): 1-11, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23225636
13.
High-capacity adenovector delivery of forced CRISPR-Cas9 heterodimers fosters precise chromosomal deletions in human cells.
Mol Ther Nucleic Acids
; 31: 746-762, 2023 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36937620
14.
Transcription factor rational design improves directed differentiation of human mesenchymal stem cells into skeletal myocytes.
Mol Ther
; 19(7): 1331-41, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21266958
15.
High-Capacity Adenoviral Vectors Permit Robust and Versatile Testing of DMD Gene Repair Tools and Strategies in Human Cells.
Cells
; 9(4)2020 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32252479
16.
ATF3 and Fra1 have opposite functions in JNK- and ERK-dependent DNA damage responses.
DNA Repair (Amst)
; 7(3): 487-96, 2008 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18249159
17.
The Chromatin Structure of CRISPR-Cas9 Target DNA Controls the Balance between Mutagenic and Homology-Directed Gene-Editing Events.
Mol Ther Nucleic Acids
; 16: 141-154, 2019 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30884291
18.
In trans paired nicking triggers seamless genome editing without double-stranded DNA cutting.
Nat Commun
; 8(1): 657, 2017 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28939824
19.
DNA damage in transcribed genes induces apoptosis via the JNK pathway and the JNK-phosphatase MKP-1.
Oncogene
; 24(48): 7135-44, 2005 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-16044158
20.
Adenoviral vectors encoding CRISPR/Cas9 multiplexes rescue dystrophin synthesis in unselected populations of DMD muscle cells.
Sci Rep
; 6: 37051, 2016 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27845387