Detalhe da pesquisa
1.
The novel bronchodilator navafenterol: a phase 2a, multicentre, randomised, double-blind, placebo-controlled crossover trial in COPD.
Eur Respir J
; 59(4)2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34503985
2.
Characterization of Clinical Absorption, Distribution, Metabolism, and Excretion and Pharmacokinetics of Velsecorat Using an Intravenous Microtracer Combined with an Inhaled Dose in Healthy Subjects.
Drug Metab Dispos
; 50(2): 150-157, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34853068
3.
Focused Information Criterion for Restricted Mean Survival Times: Non-Parametric or Parametric Estimators.
Entropy (Basel)
; 24(5)2022 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35626596
4.
Uncertainty quantification, propagation and characterization by Bayesian analysis combined with global sensitivity analysis applied to dynamical intracellular pathway models.
Bioinformatics
; 35(2): 284-292, 2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30010712
5.
Improving the evaluation of COPD exacerbation treatment effects by accounting for early treatment discontinuations: a post-hoc analysis of randomized clinical trials.
Respir Res
; 21(1): 158, 2020 Jun 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32571311
6.
Normalization of metabolomics data with applications to correlation maps.
Bioinformatics
; 30(15): 2155-61, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24711654
7.
A Randomized Trial of Dual-Acting Bronchodilator AZD8871 for Chronic Obstructive Pulmonary Disease.
Am J Respir Crit Care Med
; 199(10): 1282-1284, 2019 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30768909
8.
Transcriptional and metabolic data integration and modeling for identification of active pathways.
Biostatistics
; 13(4): 748-61, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22699861
9.
mRNA stability changes precede changes in steady-state mRNA amounts during hyperosmotic stress.
RNA
; 15(4): 600-14, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19223440
10.
Complexity of design in early phase respiratory clinical trials; evaluating impact of primary endpoints and sponsor size.
Contemp Clin Trials Commun
; 22: 100793, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-34136720
11.
The cost-effectiveness of prostate cancer screening using the Stockholm3 test.
PLoS One
; 16(2): e0246674, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33630863
12.
Longitudinal FEV1 and Exacerbation Risk in COPD: Quantifying the Association Using Joint Modelling.
Int J Chron Obstruct Pulmon Dis
; 16: 101-111, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33488073
13.
COPDCompEx: A novel composite endpoint for COPD exacerbations to enable faster clinical development.
Respir Med
; 173: 106175, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33032168
14.
Impact of season and geography on CompEx Asthma: a composite end-point for exacerbations.
ERJ Open Res
; 6(4)2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-33123561
15.
A natural history model for planning prostate cancer testing: Calibration and validation using Swedish registry data.
PLoS One
; 14(2): e0211918, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30763406
16.
Dipeptidyl Peptidase 1 Inhibitor AZD7986 Induces a Sustained, Exposure-Dependent Reduction in Neutrophil Elastase Activity in Healthy Subjects.
Clin Pharmacol Ther
; 104(6): 1155-1164, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29484635
17.
Exploration of human brain tumour metabolism using pairwise metabolite-metabolite correlation analysis (MMCA) of HR-MAS 1H NMR spectra.
PLoS One
; 12(10): e0185980, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29069098
18.
A novel endpoint for exacerbations in asthma to accelerate clinical development: a post-hoc analysis of randomised controlled trials.
Lancet Respir Med
; 5(7): 577-590, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28583396
19.
E-Science technologies in a workflow for personalized medicine using cancer screening as a case study.
J Am Med Inform Assoc
; 24(5): 950-957, 2017 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28444384
20.
COPD biomarkers as tools for decision making in early clinical drug development.
Biomark Med
; 10(5): 513-24, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27128658