[Oral desensitization to antitubercular agents]. / Désensibilisation orale aux anti-tuberculeux.

We report a case of hypersensitivity reaction to majors antituberculosis drugs. We have successfully performed oral desensitization to "Rifater *". We present our protocol that we compare to those proposed in the literature.

[The role of phadiatop in the screening of respiratory allergy]. / Place du phadiatop dans le dépistage de l'allergie respiratoire.

Phadiatop is a new in vitro screening test for respiratory allergy. This test, based on the RAST procedure, detects in serum, the presence of specific IgE to a mixture of common inhalent allergens. Among 70 patients (26 children and 44 adults) consulting for respiratory syndrome, Phadiatop was positive in 31 cases. There were a good correlation between this new test and skin tests (59% for adults and 92% for children), total IgE (70% for adults and 65% for children) and RAST (93% for adults and 96% for children). Phadiatop, with a specificity of 100%, a sensitivity of 82% (76% for adults and 92% for children) and an efficiency of 90% (86% for adults and 96% for children), is a more accurate test than total IgE and could be an excellent in vitro screening test for respiratory allergy.

[Human basophil degranulation test and double diffusion in pulmonary hydatidosis]. / Test de dégranulation des basophiles humains et double diffusion dans l'hydatidose pulmonaire.

A slide human basophil degranulation test (HBDT) and a double-diffusion test were done in 37 patients with suspected pulmonary hydatid disease. Among the 31 patients in whom a diagnosis was firmly established, 22 had a pulmonary hydatid cyst and 9 did not (controls). The HBDT was at least 35% in 17 of the 22 patients with hydatid disease; 16 of these exhibited a precipitation arc. Among the 9 controls, none had a HBDT above 30% and three had a precipitation arc. In this localization of hydatid disease, compared to the double-diffusion technique, the HBDT has similar sensitivity (0.77 versus 0.73 but higher specificity (1 versus 0.67).

[Pulmonary alveolar microlithiasis. Apropos of a case]. / La microlithiase alvéolaire pulmonaire. A propos d'un cas.

The pulmonary alveolar microlithiasis is an affection characterized by the presence, in the alveolar light, of calcified deposits or "microliths". It is a rare affection as there is now about 200 cases in the world. We report the case of a pulmonary alveolar microlithiasis discovered in a patient of 25 years old and demonstrated histologically by transbronchial lung biopsy under flexible bronchoscope.