Detalhe da pesquisa
1.
Development and profiling of mGlu7 NAMs with a range of saturable inhibition of agonist responses in vitro.
Bioorg Med Chem Lett
; 74: 128923, 2022 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35944850
2.
Synthesis and SAR of a series of mGlu7 NAMs based on an ethyl-8-methoxy-4-(4-phenylpiperazin-1-yl)quinoline carboxylate core.
Bioorg Med Chem Lett
; 30(22): 127529, 2020 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32890686
3.
Discovery of a novel 2,3-dimethylimidazo[1,2-a]pyrazine-6-carboxamide M4 positive allosteric modulator (PAM) chemotype.
Bioorg Med Chem Lett
; 30(3): 126812, 2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31784320
4.
Surveying heterocycles as amide bioisosteres within a series of mGlu7 NAMs: Discovery of VU6019278.
Bioorg Med Chem Lett
; 29(10): 1211-1214, 2019 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30910459
5.
Discovery of a novel 3,4-dimethylcinnoline carboxamide M4 positive allosteric modulator (PAM) chemotype via scaffold hopping.
Bioorg Med Chem Lett
; 29(21): 126678, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31537424
6.
Multiomic Profiling of Human Clonal Hematopoiesis Reveals Genotype and Cell-Specific Inflammatory Pathway Activation.
Blood Adv
; 2024 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38507736
7.
Isocitrate dehydrogenase mutations are associated with altered IL-1ß responses in acute myeloid leukemia.
Leukemia
; 36(4): 923-934, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34857894
8.
The delta isoform of phosphatidylinositol-3-kinase predominates in chronic myelomonocytic leukemia and can be targeted effectively with umbralisib and ruxolitinib.
Exp Hematol
; 97: 57-65.e5, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33617893
9.
Phenotypic profiling of mGlu7 knockout mice reveals new implications for neurodevelopmental disorders.
Genes Brain Behav
; 19(7): e12654, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32248644
10.
Discovery of an Orally Bioavailable and Central Nervous System (CNS) Penetrant mGlu7 Negative Allosteric Modulator (NAM) in Vivo Tool Compound: N-(2-(1 H-1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl)-4-(cyclopropylmethoxy)-3-methoxybenzamide (VU6012962).
J Med Chem
; 62(3): 1690-1695, 2019 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30608678
11.
Correlation between the Functional Movement Screen and Hip Mobility in NCAA Division II Athletes.
Int J Exerc Sci
; 10(4): 541-549, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29170690
12.
ASHP Statement on Telehealth Pharmacy Practice.
Am J Health Syst Pharm
; 79(19): 1728-1735, 2022 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35866463
13.
ASHP Statement on Telepharmacy.
Am J Health Syst Pharm
; 74(9): e236-e241, 2017 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28438829