Detalhe da pesquisa
1.
Phase II study of gemcitabine, oxaliplatin and capecitabine in patients with KRAS exon 2 mutated biliary tract cancers.
Acta Oncol
; 59(3): 298-301, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-31838939
2.
High-dose chemoradiotherapy and watchful waiting for distal rectal cancer: a prospective observational study.
Lancet Oncol
; 16(8): 919-27, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26156652
3.
Neoadjuvant chemotherapy in locally advanced colon cancer. A phase II trial.
Acta Oncol
; 54(10): 1747-53, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25920359
4.
Dynamic contrast-enhanced computed tomography as a potential biomarker in patients with metastatic colorectal cancer treated with regorafenib.
Acta Radiol
; 60(7): 836-845, 2019 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-30348001
5.
Combining sCD163 with CA 19-9 Increases the Predictiveness of Pancreatic Ductal Adenocarcinoma.
Cancers (Basel)
; 15(3)2023 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36765852
6.
The Soluble Urokinase-Type Plasminogen Activator Receptor as a Biomarker for Survival and Early Treatment Effect in Metastatic Colorectal Cancer.
Cancers (Basel)
; 13(20)2021 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34680247
7.
Early ctDNA response to chemotherapy. A potential surrogate marker for overall survival.
Eur J Cancer
; 149: 128-133, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33857886
8.
Early identification of treatment benefit by methylated circulating tumor DNA in metastatic colorectal cancer.
Ther Adv Med Oncol
; 12: 1758835920918472, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32518596
9.
Serum IL6 as a Prognostic Biomarker and IL6R as a Therapeutic Target in Biliary Tract Cancers.
Clin Cancer Res
; 26(21): 5655-5667, 2020 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32933994
10.
Evaluation of the topoisomerase II-inactive bisdioxopiperazine ICRF-161 as a protectant against doxorubicin-induced cardiomyopathy.
Toxicology
; 255(1-2): 72-9, 2009 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-19010377
11.
Predictive value of MSH2 gene expression in colorectal cancer treated with capecitabine.
Clin Colorectal Cancer
; 6(6): 433-5, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17531106
12.
Substituted purine analogues define a novel structural class of catalytic topoisomerase II inhibitors.
Cancer Res
; 65(16): 7470-7, 2005 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16103101
13.
Combining etoposide and dexrazoxane synergizes with radiotherapy and improves survival in mice with central nervous system tumors.
Clin Cancer Res
; 11(18): 6722-9, 2005 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16166453
14.
Decline in CA19-9 during chemotherapy predicts survival in four independent cohorts of patients with inoperable bile duct cancer.
Eur J Cancer
; 51(11): 1381-8, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25971532
15.
Human small cell lung cancer NYH cells resistant to the bisdioxopiperazine ICRF-187 exhibit a functional dominant Tyr165Ser mutation in the Walker A ATP binding site of topoisomerase II alpha.
FEBS Lett
; 520(1-3): 161-6, 2002 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-12044890
16.
A dual mechanism of action of the anticancer agent F 11782 on human topoisomerase II alpha.
Biochem Pharmacol
; 66(4): 623-31, 2003 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12906927
17.
Characterisation of cytotoxicity and DNA damage induced by the topoisomerase II-directed bisdioxopiperazine anti-cancer agent ICRF-187 (dexrazoxane) in yeast and mammalian cells.
BMC Pharmacol
; 4: 31, 2004 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-15575955
18.
A mouse model for studying the interaction of bisdioxopiperazines with topoisomerase IIalpha in vivo.
Mol Pharmacol
; 72(4): 1003-14, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17622580
19.
A three-dimensional quantitative structure-activity relationship study of the inhibition of the ATPase activity and the strand passing catalytic activity of topoisomerase IIalpha by substituted purine analogs.
Mol Pharmacol
; 70(5): 1503-13, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16880287
20.
Quantitative proteomic analysis of post-translational modifications of human histones.
Mol Cell Proteomics
; 5(7): 1314-25, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16627869