Detalhe da pesquisa
1.
Adaptive Mutations Enhance Assembly and Cell-to-Cell Transmission of a High-Titer Hepatitis C Virus Genotype 5a Core-NS2 JFH1-Based Recombinant.
J Virol
; 89(15): 7758-75, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25995244
2.
Neutralization resistance of hepatitis C virus can be overcome by recombinant human monoclonal antibodies.
Hepatology
; 58(5): 1587-97, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23729237
3.
MicroRNA-122 antagonism against hepatitis C virus genotypes 1-6 and reduced efficacy by host RNA insertion or mutations in the HCV 5' UTR.
Proc Natl Acad Sci U S A
; 108(12): 4991-6, 2011 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21383155
4.
Adapted J6/JFH1-based Hepatitis C virus recombinants with genotype-specific NS4A show similar efficacies against lead protease inhibitors, alpha interferon, and a putative NS4A inhibitor.
Antimicrob Agents Chemother
; 57(12): 6034-49, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24060868
5.
Recombinant HCV variants with NS5A from genotypes 1-7 have different sensitivities to an NS5A inhibitor but not interferon-α.
Gastroenterology
; 140(3): 1032-42, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21111742
6.
Differential efficacy of protease inhibitors against HCV genotypes 2a, 3a, 5a, and 6a NS3/4A protease recombinant viruses.
Gastroenterology
; 141(3): 1067-79, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21699793
7.
Hypervariable region 1 differentially impacts viability of hepatitis C virus strains of genotypes 1 to 6 and impairs virus neutralization.
J Virol
; 85(5): 2224-34, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21123377
8.
Efficient culture adaptation of hepatitis C virus recombinants with genotype-specific core-NS2 by using previously identified mutations.
J Virol
; 85(6): 2891-906, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21177811
9.
Development and application of hepatitis C reporter viruses with genotype 1 to 7 core-nonstructural protein 2 (NS2) expressing fluorescent proteins or luciferase in modified JFH1 NS5A.
J Virol
; 85(17): 8913-28, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21697486
10.
Development of JFH1-based cell culture systems for hepatitis C virus genotype 4a and evidence for cross-genotype neutralization.
Proc Natl Acad Sci U S A
; 105(3): 997-1002, 2008 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-18195353
11.
Development and characterization of hepatitis C virus genotype 1-7 cell culture systems: role of CD81 and scavenger receptor class B type I and effect of antiviral drugs.
Hepatology
; 49(2): 364-77, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19148942
12.
Development of a downstream process for the production of an inactivated whole hepatitis C virus vaccine.
Sci Rep
; 10(1): 16261, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33004836
13.
Recombinant hepatitis C virus genotype 5a infectious cell culture systems expressing minimal JFH1 NS5B sequences permit polymerase inhibitor studies.
Virology
; 522: 177-192, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30032031
14.
Production and characterization of high-titer serum-free cell culture grown hepatitis C virus particles of genotype 1-6.
Virology
; 458-459: 190-208, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24928051
15.
Neutralizing antibodies in patients with chronic hepatitis C, genotype 1, against a panel of genotype 1 culture viruses: lack of correlation to treatment outcome.
PLoS One
; 8(5): e62674, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23667506
16.
Highly efficient JFH1-based cell-culture system for hepatitis C virus genotype 5a: failure of homologous neutralizing-antibody treatment to control infection.
J Infect Dis
; 198(12): 1756-65, 2008 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19032070