Detalhe da pesquisa
1.
PKAN pathogenesis and treatment.
Mol Genet Metab
; 137(3): 283-291, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36240582
2.
Elevated FGF21 secretion, PGC-1α and ketogenic enzyme expression are hallmarks of iron-sulfur cluster depletion in human skeletal muscle.
Hum Mol Genet
; 23(1): 24-39, 2014 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23943793
3.
Pallidal neuronal apolipoprotein E in pantothenate kinase-associated neurodegeneration recapitulates ischemic injury to the globus pallidus.
Mol Genet Metab
; 116(4): 289-97, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26547561
4.
Tissue specificity of a human mitochondrial disease: differentiation-enhanced mis-splicing of the Fe-S scaffold gene ISCU renders patient cells more sensitive to oxidative stress in ISCU myopathy.
J Biol Chem
; 287(48): 40119-30, 2012 Nov 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23035118
5.
Cardiac glycosides restore autophagy flux in an iPSC-derived neuronal model of WDR45 deficiency.
bioRxiv
; 2023 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37745522
6.
Dysregulation of Iron Homeostasis in the Central Nervous System and the Role of Ferroptosis in Neurodegenerative Disorders.
Antioxid Redox Signal
; 37(1-3): 150-170, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34569265
7.
Dysregulation of iron homeostasis in the CNS contributes to disease progression in a mouse model of amyotrophic lateral sclerosis.
J Neurosci
; 29(3): 610-9, 2009 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-19158288
8.
Ceruloplasmin protects injured spinal cord from iron-mediated oxidative damage.
J Neurosci
; 28(48): 12736-47, 2008 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-19036966
9.
Brain iron homeostasis, the choroid plexus, and localization of iron transport proteins.
Metab Brain Dis
; 24(4): 673-84, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19851851
10.
4'-Phosphopantetheine corrects CoA, iron, and dopamine metabolic defects in mammalian models of PKAN.
EMBO Mol Med
; 11(12): e10489, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31660701
11.
Autosomal dominant mitochondrial membrane protein-associated neurodegeneration (MPAN).
Mol Genet Genomic Med
; 7(7): e00736, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31087512
12.
Age-related changes in iron homeostasis and cell death in the cerebellum of ceruloplasmin-deficient mice.
J Neurosci
; 26(38): 9810-9, 2006 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-16988052
13.
Ceruloplasmin regulates iron levels in the CNS and prevents free radical injury.
J Neurosci
; 22(15): 6578-86, 2002 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12151537
14.
Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α.
Cell Metab
; 17(2): 271-81, 2013 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23395173
15.
Primary cilia utilize glycoprotein-dependent adhesion mechanisms to stabilize long-lasting cilia-cilia contacts.
Cilia
; 1(1): 3, 2012 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23351752
16.
Iron accumulation in deep cortical layers accounts for MRI signal abnormalities in ALS: correlating 7 tesla MRI and pathology.
PLoS One
; 7(4): e35241, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22529995
17.
Iron insufficiency compromises motor neurons and their mitochondrial function in Irp2-null mice.
PLoS One
; 6(10): e25404, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22003390
18.
The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels.
Cancer Cell
; 20(3): 315-27, 2011 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21907923
19.
Glutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblasts.
J Clin Invest
; 120(5): 1749-61, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20364084
20.
The protective effects of 15-deoxy-delta-(12,14)-prostaglandin J2 in spinal cord injury.
Glia
; 56(4): 436-48, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18205174