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Anal Bioanal Chem ; 392(5): 955-68, 2008 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-18758762

RESUMO

European Council Directive 98/83/EC on the quality of water intended for human consumption brought a new challenge for water-quality control routine laboratories, mainly on pesticides analysis. Under the guidelines of ISO/IEC 17025:2005, a multiresidue method was developed, validated, implemented in routine, and studied with real samples during a one-year period. The proposed method enables routine laboratories to handle a large number of samples, since 28 pesticides of 14 different chemical groups can be quantitated in a single procedure. The method comprises a solid-phase extraction step and subsequent analysis by liquid chromatography-mass spectrometry (LC-MS-MS). The accuracy was established on the basis of participation in interlaboratory proficiency tests, with encouraging results (majority |z-score| <2), and the precision was consistently analysed over one year. The limits of quantitation (below 0.050 microg L(-1)) are in agreement with the enforced threshold value for pesticides of 0.10 microg L(-1). Overall method performance is suitable for routine use according to accreditation rules, taking into account the data collected over one year.


Assuntos
Cromatografia Líquida/métodos , Espectrometria de Massas/métodos , Resíduos de Praguicidas/análise , Extração em Fase Sólida/métodos , Poluentes Químicos da Água/análise , Abastecimento de Água/análise , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
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