Detalhe da pesquisa
1.
Corrigendum: Nuclear PKM2 regulates ß-catenin transactivation upon EGFR activation.
Nature
; 550(7674): 142, 2017 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28953868
2.
Characterization of Hydrophilic α-Helical Hot Spots on the Protein-Protein Interaction Interfaces for the Design of α-Helix Mimetics.
J Chem Inf Model
; 62(8): 1873-1890, 2022 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35385659
3.
Fragment hopping protocol for the design of small-molecule protein-protein interaction inhibitors.
Bioorg Med Chem
; 69: 116879, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35749838
4.
Inhibition of ß-catenin/B cell lymphoma 9 protein-protein interaction using α-helix-mimicking sulfono-γ-AApeptide inhibitors.
Proc Natl Acad Sci U S A
; 116(22): 10757-10762, 2019 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31088961
5.
Direct targeting of ß-catenin in the Wnt signaling pathway: Current progress and perspectives.
Med Res Rev
; 41(4): 2109-2129, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33475177
6.
Preclinical evaluation of [225Ac]Ac-DOTA-TATE for treatment of lung neuroendocrine neoplasms.
Eur J Nucl Med Mol Imaging
; 48(11): 3408-3421, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33772332
7.
Synthesis and structural characterization of a monocarboxylic inhibitor for GRB2 SH2 domain.
Bioorg Med Chem Lett
; 51: 128354, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34506932
8.
EGFR phosphorylates FAM129B to promote Ras activation.
Proc Natl Acad Sci U S A
; 113(3): 644-9, 2016 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26721396
9.
AKR1B10 activates diacylglycerol (DAG) second messenger in breast cancer cells.
Mol Carcinog
; 57(10): 1300-1310, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29846015
10.
Ruthenium-Catalyzed C-H Allylation of Alkenes with Allyl Alcohols via C-H Bond Activation in Aqueous Solution.
J Org Chem
; 83(19): 12094-12102, 2018 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30212630
11.
Rhodium-Catalyzed [4 + 1] Cyclization via C-H Activation for the Synthesis of Divergent Heterocycles Bearing a Quaternary Carbon.
J Org Chem
; 83(8): 4650-4656, 2018 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29608841
12.
Rhodium(iii)-catalyzed C-H allylation of indoles with allyl alcohols via ß-hydroxide elimination.
Org Biomol Chem
; 16(31): 5691-5698, 2018 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30047974
13.
Nuclear PKM2 regulates ß-catenin transactivation upon EGFR activation.
Nature
; 480(7375): 118-22, 2011 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22056988
14.
EGF-induced ERK activation promotes CK2-mediated disassociation of alpha-Catenin from beta-Catenin and transactivation of beta-Catenin.
Mol Cell
; 36(4): 547-59, 2009 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-19941816
15.
Rational design of selective small-molecule inhibitors for ß-catenin/B-cell lymphoma 9 protein-protein interactions.
J Am Chem Soc
; 137(38): 12249-60, 2015 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-26352795
16.
AlphaScreen selectivity assay for ß-catenin/B-cell lymphoma 9 inhibitors.
Anal Biochem
; 469: 43-53, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25312469
17.
The mobility of a conserved tyrosine residue controls isoform-dependent enzyme-inhibitor interactions in nitric oxide synthases.
Biochemistry
; 53(32): 5272-9, 2014 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25089924
18.
Differential regulation of c-Jun protein plays an instrumental role in chemoresistance of cancer cells.
J Biol Chem
; 288(27): 19321-9, 2013 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23678002
19.
AKT-dependent phosphorylation of Niban regulates nucleophosmin- and MDM2-mediated p53 stability and cell apoptosis.
EMBO Rep
; 13(6): 554-60, 2012 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22510990
20.
Hot spot-based design of small-molecule inhibitors for protein-protein interactions.
Bioorg Med Chem Lett
; 24(11): 2546-54, 2014 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24751445