Detalhe da pesquisa
1.
PGRN deficiency exacerbates, whereas a brain penetrant PGRN derivative protects, GBA1 mutation-associated pathologies and diseases.
Proc Natl Acad Sci U S A
; 120(1): e2210442120, 2023 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36574647
2.
Progranulin: A key player in autoimmune diseases.
Cytokine
; 101: 48-55, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27527809
3.
IKK-ß/NF-κB p65 mediates p27(Kip1) protein degradation in arsenite response.
Biochem Biophys Res Commun
; 447(4): 563-8, 2014 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24751519
4.
Progranulinopathy: A diverse realm of disorders linked to progranulin imbalances.
Cytokine Growth Factor Rev
; 76: 142-159, 2024 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37981505
5.
A systematic review of progranulin concentrations in biofluids in over 7,000 people-assessing the pathogenicity of GRN mutations and other influencing factors.
Alzheimers Res Ther
; 16(1): 66, 2024 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38539243
6.
A link between premenopausal iron deficiency and breast cancer malignancy.
BMC Cancer
; 13: 307, 2013 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-23800380
7.
Laboratory studies of the impact of calcite on in vitro and in vivo effects of coal dust: a potential preventive agent for coal workers' pneumoconiosis?
Am J Ind Med
; 56(3): 292-9, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22976941
8.
Menopause increases the iron storage protein ferritin in skin.
J Cosmet Sci
; 64(3): 175-9, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23752032
9.
Interaction with ERp57 is required for progranulin protection against Type 2 Gaucher disease.
Biosci Trends
; 17(2): 126-135, 2023 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36889696
10.
Src regulates Tyr(20) phosphorylation of transferrin receptor-1 and potentiates breast cancer cell survival.
J Biol Chem
; 286(41): 35708-35715, 2011 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21859709
11.
Efficacy and Safety of a Krabbe Disease Gene Therapy.
Hum Gene Ther
; 33(9-10): 499-517, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35333110
12.
Iron sensitizes keratinocytes and fibroblasts to UVA-mediated matrix metalloproteinase-1 through TNF-α and ERK activation.
Exp Dermatol
; 20(3): 249-54, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20701626
13.
Protection against ultraviolet A-induced oxidative damage in normal human epidermal keratinocytes under post-menopausal conditions by an ultraviolet A-activated caged-iron chelator: a pilot study.
Photodermatol Photoimmunol Photomed
; 27(5): 231-5, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21950626
14.
Progranulin associates with Rab2 and is involved in autophagosome-lysosome fusion in Gaucher disease.
J Mol Med (Berl)
; 99(11): 1639-1654, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34453183
15.
Effects of cellular iron deficiency on the formation of vascular endothelial growth factor and angiogenesis. Iron deficiency and angiogenesis.
Cancer Cell Int
; 10: 28, 2010 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-20723262
16.
Progranulin inhibition of TNFα.
Immunol Cell Biol
; 92(4): 299-300, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24518982
17.
PI-3K/Akt pathway-dependent cyclin D1 expression is responsible for arsenite-induced human keratinocyte transformation.
Environ Health Perspect
; 116(1): 1-6, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18197291
18.
Roles of hormone replacement therapy and iron in proliferation of breast epithelial cells with different estrogen and progesterone receptor status.
Breast
; 17(2): 172-9, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17928227
19.
RNA-Seq analysis of interferon inducible p204-mediated network in anti-tumor immunity.
Sci Rep
; 8(1): 6495, 2018 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29691417
20.
Progranulin associates with hexosaminidase A and ameliorates GM2 ganglioside accumulation and lysosomal storage in Tay-Sachs disease.
J Mol Med (Berl)
; 96(12): 1359-1373, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30341570