Detalhe da pesquisa
1.
SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome.
Mol Cell
; 44(2): 177-90, 2011 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21856199
2.
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.
Nature
; 464(7285): 121-5, 2010 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-20203611
3.
Platform-independent and label-free quantitation of proteomic data using MS1 extracted ion chromatograms in skyline: application to protein acetylation and phosphorylation.
Mol Cell Proteomics
; 11(5): 202-14, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22454539
4.
Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production.
Proc Natl Acad Sci U S A
; 108(35): 14608-13, 2011 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21873205
5.
Bone morphogenetic protein 7 (BMP7) reverses obesity and regulates appetite through a central mTOR pathway.
FASEB J
; 26(5): 2187-96, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22331196
6.
SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation.
Cell Metab
; 6(2): 105-14, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17681146
7.
Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation.
Biochem J
; 433(3): 505-14, 2011 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21044047
8.
Antisense oligonucleotide modulation of non-productive alternative splicing upregulates gene expression.
Nat Commun
; 11(1): 3501, 2020 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32647108
9.
Hsp90ß knockdown in DIO mice reverses insulin resistance and improves glucose tolerance.
Nutr Metab (Lond)
; 15: 11, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29434648
10.
Deletion of the Nhlh2 transcription factor decreases the levels of the anorexigenic peptides alpha melanocyte-stimulating hormone and thyrotropin-releasing hormone and implicates prohormone convertases I and II in obesity.
Endocrinology
; 145(4): 1503-13, 2004 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-14701669
11.
Reduced voluntary activity precedes adult-onset obesity in Nhlh2 knockout mice.
Physiol Behav
; 77(2-3): 387-402, 2002 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-12419415
12.
Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation.
Diabetes
; 62(10): 3404-17, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23835326
13.
Diabetes and insulin in regulation of brain cholesterol metabolism.
Cell Metab
; 12(6): 567-79, 2010 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21109190
14.
Hepatic insulin resistance directly promotes formation of cholesterol gallstones.
Nat Med
; 14(7): 778-82, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18587407