Pesquisa | Portal de Pesquisa da BVS

1.

USP10: friend and foe.

Jochemsen, Aart G; Shiloh, Yosef.

Cell ; 140(3): 308-10, 2010 Feb 05.

Artigo em Inglês | MEDLINE | ID: mdl-20144755

2.

Overexpression of EZH2 in conjunctival melanoma offers a new therapeutic target.

Cao, Jinfeng; Pontes, Kelly Cs; Heijkants, Renier C; Brouwer, Niels J; Groenewoud, Arwin; Jordanova, Ekaterina S; Marinkovic, Marina; van Duinen, Sjoerd; Teunisse, Amina Fas; Verdijk, Robert M; Snaar-Jagalska, Ewa; Jochemsen, Aart G; Jager, Martine J.

J Pathol ; 245(4): 433-444, 2018 08.

Artigo em Inglês | MEDLINE | ID: mdl-29732557

3.

Functional analyses of a human vascular tumor FOS variant identify a novel degradation mechanism and a link to tumorigenesis.

van IJzendoorn, David G P; Forghany, Zary; Liebelt, Frauke; Vertegaal, Alfred C; Jochemsen, Aart G; Bovée, Judith V M G; Szuhai, Karoly; Baker, David A.

J Biol Chem ; 292(52): 21282-21290, 2017 12 29.

Artigo em Inglês | MEDLINE | ID: mdl-29150442

4.

Fluorescent CXCR4 targeting peptide as alternative for antibody staining in Ewing sarcoma.

Sand, Laurens G L; Buckle, Tessa; van Leeuwen, Fijs W B; Corver, Willem E; Kruisselbrink, Alwine B; Jochemsen, Aart G; Hogendoorn, Pancras C W; Szuhai, Károly.

BMC Cancer ; 17(1): 383, 2017 05 26.

Artigo em Inglês | MEDLINE | ID: mdl-28549419

5.

Ewing sarcoma inhibition by disruption of EWSR1-FLI1 transcriptional activity and reactivation of p53.

van der Ent, Wietske; Jochemsen, Aart G; Teunisse, Amina F A S; Krens, S F Gabriel; Szuhai, Karoly; Spaink, Herman P; Hogendoorn, Pancras C W; Snaar-Jagalska, B Ewa.

J Pathol ; 233(4): 415-24, 2014 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-24974828

6.

Wild-type p53 inhibits pro-invasive properties of TGF-ß3 in breast cancer, in part through regulation of EPHB2, a new TGF-ß target gene.

Lam, Suzanne; Wiercinska, Eliza; Teunisse, Amina F A S; Lodder, Kirsten; ten Dijke, Peter; Jochemsen, Aart G.

Breast Cancer Res Treat ; 148(1): 7-18, 2014 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-25257729

7.

Reactivation of p53 as therapeutic intervention for malignant melanoma.

Jochemsen, Aart G.

Curr Opin Oncol ; 26(1): 114-9, 2014 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-24275854

8.

Combined Mcl-1 and YAP1/TAZ inhibition for treatment of metastatic uveal melanoma.

Glinkina, Kseniya A; Teunisse, Amina F A S; Gelmi, Maria Chiara; de Vries, Jelle; Jager, Martine J; Jochemsen, Aart G.

Melanoma Res ; 33(5): 345-356, 2023 10 01.

Artigo em Inglês | MEDLINE | ID: mdl-37467061

9.

Patient-derived zebrafish xenografts of uveal melanoma reveal ferroptosis as a drug target.

Groenewoud, Arwin; Yin, Jie; Gelmi, Maria Chiara; Alsafadi, Samar; Nemati, Fariba; Decaudin, Didier; Roman-Roman, Sergio; Kalirai, Helen; Coupland, Sarah E; Jochemsen, Aart G; Jager, Martine J; Engel, Felix B; Snaar-Jagalska, B E.

Cell Death Discov ; 9(1): 183, 2023 Jun 16.

Artigo em Inglês | MEDLINE | ID: mdl-37321991

10.

FAK Inhibitor-Based Combinations with MEK or PKC Inhibitors Trigger Synergistic Antitumor Effects in Uveal Melanoma.

Tarin, Malcy; Némati, Fariba; Decaudin, Didier; Canbezdi, Christine; Marande, Benjamin; Silva, Lisseth; Derrien, Héloïse; Jochemsen, Aart G; Gardrat, Sophie; Piperno-Neumann, Sophie; Rodrigues, Manuel; Mariani, Pascale; Cassoux, Nathalie; Stern, Marc-Henri; Roman-Roman, Sergio; Alsafadi, Samar.

Cancers (Basel) ; 15(8)2023 Apr 13.

Artigo em Inglês | MEDLINE | ID: mdl-37190207

11.

Zebrafish Patient-Derived Xenograft Model as a Preclinical Platform for Uveal Melanoma Drug Discovery.

Yin, Jie; Zhao, Gangyin; Kalirai, Helen; Coupland, Sarah E; Jochemsen, Aart G; Forn-Cuní, Gabriel; Wierenga, Annemijn P A; Jager, Martine J; Snaar-Jagalska, B Ewa; Groenewoud, Arwin.

Pharmaceuticals (Basel) ; 16(4)2023 Apr 15.

Artigo em Inglês | MEDLINE | ID: mdl-37111355

12.

Inactivation of the p53 pathway in retinoblastoma.

Laurie, Nikia A; Donovan, Stacy L; Shih, Chie-Schin; Zhang, Jiakun; Mills, Nicholas; Fuller, Christine; Teunisse, Amina; Lam, Suzanne; Ramos, Yolande; Mohan, Adithi; Johnson, Dianna; Wilson, Matthew; Rodriguez-Galindo, Carlos; Quarto, Micaela; Francoz, Sarah; Mendrysa, Susan M; Guy, R Kiplin; Marine, Jean-Christophe; Jochemsen, Aart G; Dyer, Michael A.

Nature ; 444(7115): 61-6, 2006 Nov 02.

Artigo em Inglês | MEDLINE | ID: mdl-17080083

13.

Novel Treatments of Uveal Melanoma Identified with a Synthetic Lethal CRISPR/Cas9 Screen.

Glinkina, Kseniya; Groenewoud, Arwin; Teunisse, Amina F A S; Snaar-Jagalska, B Ewa; Jochemsen, Aart G.

Cancers (Basel) ; 14(13)2022 Jun 29.

Artigo em Inglês | MEDLINE | ID: mdl-35804957

14.

MDMX Regulates Transcriptional Activity of p53 and FOXO Proteins to Stimulate Proliferation of Melanoma Cells.

Heijkants, Renier C; Teunisse, Amina F A S; de Jong, Danielle; Glinkina, Kseniya; Mei, Hailiang; Kielbasa, Szymon M; Szuhai, Karoly; Jochemsen, Aart G.

Cancers (Basel) ; 14(18)2022 Sep 15.

Artigo em Inglês | MEDLINE | ID: mdl-36139642

15.

Preclinical Evaluation of Trabectedin in Combination With Targeted Inhibitors for Treatment of Metastatic Uveal Melanoma.

Glinkina, Kseniya; Nemati, Fariba; Teunisse, Amina F A S; Gelmi, Maria Chiara; Etienne, Vesnie; Kuipers, Muriel J; Alsafadi, Samar; Jager, Martine J; Decaudin, Didier; Jochemsen, Aart G.

Invest Ophthalmol Vis Sci ; 63(13): 14, 2022 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-36515935

16.

Targeting MDM4 as a Novel Therapeutic Approach in Prostate Cancer Independent of p53 Status.

Mejía-Hernández, Javier Octavio; Raghu, Dinesh; Caramia, Franco; Clemons, Nicholas; Fujihara, Kenji; Riseborough, Thomas; Teunisse, Amina; Jochemsen, Aart G; Abrahmsén, Lars; Blandino, Giovanni; Russo, Andrea; Gamell, Cristina; Fox, Stephen B; Mitchell, Catherine; Takano, Elena A; Byrne, David; Miranda, Panimaya Jeffreena; Saleh, Reem; Thorne, Heather; Sandhu, Shahneen; Williams, Scott G; Keam, Simon P; Haupt, Ygal; Haupt, Sue.

Cancers (Basel) ; 14(16)2022 Aug 16.

Artigo em Inglês | MEDLINE | ID: mdl-36010941

17.

HDMX-L is expressed from a functional p53-responsive promoter in the first intron of the HDMX gene and participates in an autoregulatory feedback loop to control p53 activity.

Phillips, Anna; Teunisse, Amina; Lam, Suzanne; Lodder, Kirsten; Darley, Matthew; Emaduddin, Muhammad; Wolf, Anja; Richter, Julia; de Lange, Job; Verlaan-de Vries, Matty; Lenos, Kristiaan; Böhnke, Anja; Bartel, Frank; Blaydes, Jeremy P; Jochemsen, Aart G.

J Biol Chem ; 285(38): 29111-27, 2010 Sep 17.

Artigo em Inglês | MEDLINE | ID: mdl-20659896

18.

Identification and characterization of the first small molecule inhibitor of MDMX.

Reed, Damon; Shen, Ying; Shelat, Anang A; Arnold, Leggy A; Ferreira, Antonio M; Zhu, Fangyi; Mills, Nicholas; Smithson, David C; Regni, Catherine A; Bashford, Donald; Cicero, Samantha A; Schulman, Brenda A; Jochemsen, Aart G; Guy, R Kiplin; Dyer, Michael A.

J Biol Chem ; 285(14): 10786-96, 2010 Apr 02.

Artigo em Inglês | MEDLINE | ID: mdl-20080970

19.

Oncogenic functions of hMDMX in in vitro transformation of primary human fibroblasts and embryonic retinoblasts.

Lenos, Kristiaan; de Lange, Job; Teunisse, Amina F A S; Lodder, Kirsten; Verlaan-de Vries, Matty; Wiercinska, Eliza; van der Burg, Marja J M; Szuhai, Karoly; Jochemsen, Aart G.

Mol Cancer ; 10: 111, 2011 Sep 12.

Artigo em Inglês | MEDLINE | ID: mdl-21910853

20.

Functions of MDMX in the modulation of the p53-response.

Lenos, Kristiaan; Jochemsen, Aart G.

J Biomed Biotechnol ; 2011: 876173, 2011.

Artigo em Inglês | MEDLINE | ID: mdl-21541195

Portal de Pesquisa da BVS

Informação e Conhecimento para a Saúde

Configurar filtros

Sua seleção (0)

Formato de exportação:

Exportar: