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1.
Bone Joint J ; 98-B(10 Supple B): 16-21, 2016 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-27694511

RESUMO

AIMS: To compare the gait of unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) patients with healthy controls, using a machine-learning approach. PATIENTS AND METHODS: 145 participants (121 healthy controls, 12 patients with cruciate-retaining TKA, and 12 with mobile-bearing medial UKA) were recruited. The TKA and UKA patients were a minimum of 12 months post-operative, and matched for pattern and severity of arthrosis, age, and body mass index. Participants walked on an instrumented treadmill until their maximum walking speed was reached. Temporospatial gait parameters, and vertical ground reaction force data, were captured at each speed. Oxford knee scores (OKS) were also collected. An ensemble of trees algorithm was used to analyse the data: 27 gait variables were used to train classification trees for each speed, with a binary output prediction of whether these variables were derived from a UKA or TKA patient. Healthy control gait data was then tested by the decision trees at each speed and a final classification (UKA or TKA) reached for each subject in a majority voting manner over all gait cycles and speeds. Top walking speed was also recorded. RESULTS: 92% of the healthy controls were classified by the decision tree as a UKA, 5% as a TKA, and 3% were unclassified. There was no significant difference in OKS between the UKA and TKA patients (p = 0.077). Top walking speed in TKA patients (1.6 m/s; 1.3 to 2.1) was significantly lower than that of both the UKA group (2.2 m/s; 1.8 to 2.7) and healthy controls (2.2 m/s; 1.5 to 2.7; p < 0.001). CONCLUSION: UKA results in a more physiological gait compared with TKA, and a higher top walking speed. This difference in function was not detected by the OKS. Cite this article: Bone Joint J 2016;98-B(10 Suppl B):16-21.


Assuntos
Artroplastia do Joelho/métodos , Marcha/fisiologia , Osteoartrite do Joelho/cirurgia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos de Casos e Controles , Teste de Esforço/métodos , Humanos , Articulação do Joelho/fisiopatologia , Aprendizado de Máquina , Pessoa de Meia-Idade , Osteoartrite do Joelho/fisiopatologia , Recuperação de Função Fisiológica , Índice de Gravidade de Doença , Resultado do Tratamento , Caminhada/fisiologia , Adulto Jovem
2.
J Plast Reconstr Aesthet Surg ; 62(11): e457-8, 2009 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-19046936

RESUMO

The use of fibrin sealant to secure the mesh after a hernia repair, and to reduce seroma formation after abdominoplasty, is well recognised. However, delivery of the fibrin sealant post-abdominoplasty has proved technically difficult due to the competing demands of: (1) applying instant pressure to the fibrin sealant-containing cavity and (2) accurate suturing of the skin flaps. A new technique is proposed for the application of the fibrin sealant during abdominoplasty.


Assuntos
Parede Abdominal/cirurgia , Adesivo Tecidual de Fibrina/uso terapêutico , Hérnia Inguinal/cirurgia , Telas Cirúrgicas , Humanos , Injeções Intralesionais , Laparoscopia/métodos , Prognóstico , Medição de Risco , Prevenção Secundária , Resistência à Tração , Resultado do Tratamento
3.
Acta Psychiatr Scand ; 69(2): 175-6, 1984 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-6702478

RESUMO

Twenty-nine patients were treated with haloperidol decanoate, the dosage ranging from 100 to 300 mg i.m. once a month, with duration of treatment ranging from 3-7 months. It seems that haloperidol decanoate could be useful in schizo-affective disorder/depressed type and also in manic disorder. The investigators were impressed by the relative lack of side effects.


Assuntos
Haloperidol/análogos & derivados , Transtornos Psicóticos/tratamento farmacológico , Transtorno Bipolar/tratamento farmacológico , Transtorno Depressivo/tratamento farmacológico , Haloperidol/uso terapêutico , Humanos , Prognóstico , Transtornos Psicóticos/psicologia , Esquizofrenia/tratamento farmacológico
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