Detalhe da pesquisa
1.
Comparison of activity, structure, and dynamics of SF-1 and LRH-1 complexed with small molecule modulators.
J Biol Chem
; 299(8): 104921, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37328104
2.
Constitutively Synergistic Multiagent Drug Formulations Targeting MERTK, FLT3, and BCL-2 for Treatment of AML.
Pharm Res
; 40(9): 2133-2146, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37704893
3.
Switchable Regioselective 6-endo or 5-exo Radical Cyclization via Photoredox Catalysis.
J Am Chem Soc
; 144(9): 3776-3781, 2022 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35200024
4.
Radical Chain Reduction via Carbon Dioxide Radical Anion (CO2â¢-).
J Am Chem Soc
; 143(24): 8987-8992, 2021 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34102836
5.
Hydroarylation of Arenes via Reductive Radical-Polar Crossover.
J Am Chem Soc
; 142(20): 9163-9168, 2020 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32379445
6.
Development of a new class of liver receptor homolog-1 (LRH-1) agonists by photoredox conjugate addition.
Bioorg Med Chem Lett
; 30(16): 127293, 2020 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32631515
7.
Selective C-F Functionalization of Unactivated Trifluoromethylarenes.
J Am Chem Soc
; 141(33): 13203-13211, 2019 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31369264
8.
Catalytic Strategy for Regioselective Arylethylamine Synthesis.
J Am Chem Soc
; 141(9): 4147-4153, 2019 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30759339
9.
Catalytic Defluoroalkylation of Trifluoromethylaromatics with Unactivated Alkenes.
J Am Chem Soc
; 140(1): 163-166, 2018 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29256607
10.
Radical Hydroarylation of Functionalized Olefins and Mechanistic Investigation of Photocatalytic Pyridyl Radical Reactions.
J Am Chem Soc
; 140(45): 15525-15534, 2018 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30354095
11.
Crystal Structures of the Nuclear Receptor, Liver Receptor Homolog 1, Bound to Synthetic Agonists.
J Biol Chem
; 291(49): 25281-25291, 2016 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27694446
12.
Anti-Markovnikov Hydroarylation of Unactivated Olefins via Pyridyl Radical Intermediates.
J Am Chem Soc
; 139(19): 6582-6585, 2017 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28472584
13.
Cascade palladium catalysis: a predictable and selectable regiocontrolled synthesis of N-arylbenzimidazoles.
Angew Chem Int Ed Engl
; 52(44): 11624-7, 2013 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24038854
14.
Defluoroalkylation of Trifluoromethylarenes with Hydrazones: Rapid Access to Benzylic Difluoroarylethylamines.
Org Lett
; 25(9): 1397-1402, 2023 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36848497
15.
Constitutively synergistic multiagent drug formulations targeting MERTK, FLT3, and BCL-2 for treatment of AML.
bioRxiv
; 2023 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36993676
16.
Development of constitutively synergistic nanoformulations to enhance chemosensitivity in T-cell leukemia.
J Control Release
; 361: 470-482, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37543290
17.
Enantioselective organo-SOMO cycloadditions: a catalytic approach to complex pyrrolidines from olefins and aldehydes.
J Am Chem Soc
; 134(28): 11400-3, 2012 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-22764834
18.
A phospholipid mimetic targeting LRH-1 ameliorates colitis.
Cell Chem Biol
; 29(7): 1174-1186.e7, 2022 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35316658
19.
Differential Modulation of Nuclear Receptor LRH-1 through Targeting Buried and Surface Regions of the Binding Pocket.
J Med Chem
; 65(9): 6888-6902, 2022 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35503419
20.
Dearomatization through Photoredox Hydroarylation: Discovery of a Radical-Polar Crossover Strategy.
Org Lett
; 23(14): 5576-5580, 2021 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34232663