Detalhe da pesquisa
1.
Results of a randomized double-blind placebo-controlled Phase 2 study propose iptacopan as an alternative complement pathway inhibitor for IgA nephropathy.
Kidney Int
; 105(1): 189-199, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37914086
2.
Safety and efficacy of subcutaneous ianalumab (VAY736) in patients with primary Sjögren's syndrome: a randomised, double-blind, placebo-controlled, phase 2b dose-finding trial.
Lancet
; 399(10320): 161-171, 2022 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34861168
3.
Efficacy and safety of MAS825 (anti-IL-1ß/IL-18) in COVID-19 patients with pneumonia and impaired respiratory function.
Clin Exp Immunol
; 213(3): 265-275, 2023 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37338154
4.
DFV890: a new oral NLRP3 inhibitor-tested in an early phase 2a randomised clinical trial in patients with COVID-19 pneumonia and impaired respiratory function.
Infection
; 51(3): 641-654, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-36104613
5.
Canakinumab for the Treatment of Autoinflammatory Recurrent Fever Syndromes.
N Engl J Med
; 378(20): 1908-1919, 2018 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29768139
6.
Safety of vaccinations in patients with cryopyrin-associated periodic syndromes: a prospective registry based study.
Rheumatology (Oxford)
; 56(9): 1484-1491, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28482054
7.
Efficacy and safety of SBR759, a novel calcium-free, iron (III)-based phosphate binder, versus placebo in chronic kidney disease stage V Japanese patients on maintenance renal replacement therapy.
Clin Exp Nephrol
; 18(1): 135-43, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23670305
8.
First-in-human safety, tolerability, and pharmacokinetic results of DFV890, an oral low-molecular-weight NLRP3 inhibitor.
Clin Transl Sci
; 17(5): e13789, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38761014
9.
Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.
Kidney Int Rep
; 8(12): 2754-2764, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38106570
10.
Everolimus plus early tacrolimus minimization: a phase III, randomized, open-label, multicentre trial in renal transplantation.
Transpl Int
; 25(5): 592-602, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22471345
11.
Iptacopan monotherapy in patients with paroxysmal nocturnal hemoglobinuria: a 2-cohort open-label proof-of-concept study.
Blood Adv
; 6(15): 4450-4460, 2022 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35561315
12.
Comment on: Real-life effectiveness of canakinumab in cryoprin-associated periodic syndrome.
Rheumatology (Oxford)
; 55(7): 1340-1, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27190226
13.
Efficacy and safety of SBR759, a novel calcium-free, iron(III)-based phosphate binder, in Asian patients undergoing hemodialysis: A 12-week, randomized, open-label, dose-titration study versus sevelamer hydrochloride.
Nephrology (Carlton)
; 16(8): 743-50, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21854503
14.
Addition of iptacopan, an oral factor B inhibitor, to eculizumab in patients with paroxysmal nocturnal haemoglobinuria and active haemolysis: an open-label, single-arm, phase 2, proof-of-concept trial.
Lancet Haematol
; 8(5): e344-e354, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-33765419
15.
Adult onset Still's disease-The evidence that anti-interleukin-1 treatment is effective and well-tolerated (a comprehensive literature review).
Semin Arthritis Rheum
; 47(2): 295-302, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28757235
16.
Open-Label, Phase II Study to Assess the Efficacy and Safety of Canakinumab Treatment in Active Hyperimmunoglobulinemia D With Periodic Fever Syndrome.
Arthritis Rheumatol
; 69(8): 1679-1688, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28482144
17.
Effect of Early Everolimus-Facilitated Reduction of Tacrolimus on Efficacy and Renal Function in De Novo Liver Transplant Recipients: 24-Month Results for the North American Subpopulation.
Transplantation
; 101(2): 341-349, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-28121741
18.
Gene-expression analysis of adult-onset Still's disease and systemic juvenile idiopathic arthritis is consistent with a continuum of a single disease entity.
Pediatr Rheumatol Online J
; 13: 50, 2015 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26589963
19.
Three-year Outcomes in De Novo Liver Transplant Patients Receiving Everolimus With Reduced Tacrolimus: Follow-Up Results From a Randomized, Multicenter Study.
Transplantation
; 99(7): 1455-62, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26151607
20.
The role of everolimus in liver transplantation.
Clin Exp Gastroenterol
; 7: 329-43, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25214801