Detalhe da pesquisa
1.
Small molecule and macrocyclic pyrazole derived inhibitors of myeloperoxidase (MPO).
Bioorg Med Chem Lett
; 42: 128010, 2021 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33811992
2.
Discovery and structure activity relationships of 7-benzyl triazolopyridines as stable, selective, and reversible inhibitors of myeloperoxidase.
Bioorg Med Chem
; 28(22): 115723, 2020 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33007547
3.
Isomerization and Oxidation in the Complementarity-Determining Regions of a Monoclonal Antibody: A Study of the Modification-Structure-Function Correlations by Hydrogen-Deuterium Exchange Mass Spectrometry.
Anal Chem
; 88(4): 2041-50, 2016 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26824491
4.
Discovery of an Oxycyclohexyl Acid Lysophosphatidic Acid Receptor 1 (LPA1) Antagonist BMS-986278 for the Treatment of Pulmonary Fibrotic Diseases.
J Med Chem
; 64(21): 15549-15581, 2021 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34709814
5.
Potent Triazolopyridine Myeloperoxidase Inhibitors.
ACS Med Chem Lett
; 9(12): 1175-1180, 2018 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30613322
6.
Mapping the Binding Interface in a Noncovalent Size Variant of a Monoclonal Antibody Using Native Mass Spectrometry, Hydrogen-Deuterium Exchange Mass Spectrometry, and Computational Analysis.
J Pharm Sci
; 106(11): 3222-3229, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28634122
7.
Synchronized conformational fluctuations and binding site desolvation during molecular recognition.
Biochemistry
; 43(49): 15446-52, 2004 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-15581356
8.
Configurational entropy and cooperativity between ligand binding and dimerization in glycopeptide antibiotics.
J Am Chem Soc
; 125(13): 3988-94, 2003 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-12656635
9.
The role of configurational entropy in biochemical cooperativity.
J Am Chem Soc
; 124(14): 3490-1, 2002 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-11929222