1.
Chemistry
; 24(40): 10196-10200, 2018 Jul 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29723429
RESUMO
The ruthenium(II)-catalyzed annulation of vinylnaphthols and alkynes is described. The reaction proceeds through C-H activation, dearomatization, and alkyne insertion. This reaction affords spiro-pentacyclic naphthalenones that have biological significance in good yields.
2.
Angew Chem Int Ed Engl
; 57(2): 456-460, 2018 01 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29154498
RESUMO
The first decarbonylative insertion of an alkyne through C-H/C-C activation of six-membered compounds is reported. The Ru-catalyzed reaction of 3-hydroxy-2-phenyl-chromones with alkynes works most efficiently in the presence of the ligand PPh3 to provide spiro-indenebenzofuranones. Unlike previously reported metal-catalyzed decarbonylative annulation reactions, in the present decarbonylative annulation reaction, the annulation occurs before extrusion of carbon monoxide.