Detalhe da pesquisa
1.
Loss of epigenetic information as a cause of mammalian aging.
Cell
; 186(2): 305-326.e27, 2023 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36638792
2.
Loss of epigenetic information as a cause of mammalian aging.
Cell
; 187(5): 1312-1313, 2024 Feb 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38428398
3.
Reprogramming to recover youthful epigenetic information and restore vision.
Nature
; 588(7836): 124-129, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33268865
4.
Galactic cosmic radiation exposure causes multifaceted neurocognitive impairments.
Cell Mol Life Sci
; 80(1): 29, 2023 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36607431
5.
Novel feature selection methods for construction of accurate epigenetic clocks.
PLoS Comput Biol
; 18(8): e1009938, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35984867
6.
Optimizing preclinical models of ageing for translation to clinical trials.
Br J Clin Pharmacol
; 2023 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37675638
7.
Epigenetic changes during aging and their reprogramming potential.
Crit Rev Biochem Mol Biol
; 54(1): 61-83, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30822165
8.
Sirtuins and NAD+ in the Development and Treatment of Metabolic and Cardiovascular Diseases.
Circ Res
; 123(7): 868-885, 2018 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30355082
9.
Differences in Cardiovascular Aging in Men and Women.
Adv Exp Med Biol
; 1065: 389-411, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30051398
10.
Implementation of the mouse frailty index.
Can J Physiol Pharmacol
; 95(10): 1149-1155, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28463656
11.
Novel cardioprotection strategies for the aged heart: evidence from pre-clinical studies.
Clin Exp Pharmacol Physiol
; 43(12): 1251-1260, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27626269
12.
The intersection of frailty and metabolism.
Cell Metab
; 36(5): 893-911, 2024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38614092
13.
TIME-seq reduces time and cost of DNA methylation measurement for epigenetic clock construction.
Nat Aging
; 4(2): 261-274, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38200273
14.
Age, sex, and frailty modify the expression of common reference genes in skeletal muscle from ageing mice.
Mech Ageing Dev
; 210: 111762, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36509213
15.
Is Sex as a Biological Variable Still Being Ignored in Preclinical Aging Research?
J Gerontol A Biol Sci Med Sci
; 77(11): 2177-2180, 2022 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35172335
16.
Measurements of damage and repair of binary health attributes in aging mice and humans reveal that robustness and resilience decrease with age, operate over broad timescales, and are affected differently by interventions.
Elife
; 112022 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36409200
17.
Applying the AFRAID and FRIGHT Clocks to Novel Preclinical Mouse Models of Polypharmacy.
J Gerontol A Biol Sci Med Sci
; 77(7): 1304-1312, 2022 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35313348
18.
Preclinical frailty assessments: Phenotype and frailty index identify frailty in different mice and are variably affected by chronic medications.
Exp Gerontol
; 161: 111700, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35032570
19.
Sex differences in frailty: Comparisons between humans and preclinical models.
Mech Ageing Dev
; 198: 111546, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34324923
20.
Maladaptive Changes Associated With Cardiac Aging Are Sex-Specific and Graded by Frailty and Inflammation in C57BL/6 Mice.
J Gerontol A Biol Sci Med Sci
; 76(2): 233-243, 2021 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32857156