Detalhe da pesquisa
1.
Metabolome-wide association study on ABCA7 indicates a role of ceramide metabolism in Alzheimer's disease.
Proc Natl Acad Sci U S A
; 119(43): e2206083119, 2022 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36269859
2.
ABCA7 deficiency causes neuronal dysregulation by altering mitochondrial lipid metabolism.
Mol Psychiatry
; 2023 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38135757
3.
ABCA7 haplodeficiency disturbs microglial immune responses in the mouse brain.
Proc Natl Acad Sci U S A
; 116(47): 23790-23796, 2019 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31690660
4.
Apolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids.
Acta Neuropathol
; 142(5): 807-825, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34453582
5.
ApoE (Apolipoprotein E) in Brain Pericytes Regulates Endothelial Function in an Isoform-Dependent Manner by Modulating Basement Membrane Components.
Arterioscler Thromb Vasc Biol
; 40(1): 128-144, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31665905
6.
Dual-Modified Liposome for Targeted and Enhanced Gene Delivery into Mice Brain.
J Pharmacol Exp Ther
; 374(3): 354-365, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32561686
7.
Nerve Growth Factor Gene Delivery across the Blood-Brain Barrier to Reduce Beta Amyloid Accumulation in AD Mice.
Mol Pharm
; 17(6): 2054-2063, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32315185
8.
Selective loss of cortical endothelial tight junction proteins during Alzheimer's disease progression.
Brain
; 142(4): 1077-1092, 2019 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30770921
9.
In vitro and in vivo characterization of CPP and transferrin modified liposomes encapsulating pDNA.
Nanomedicine
; 28: 102225, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32485318
10.
Tau and apolipoprotein E modulate cerebrovascular tight junction integrity independent of cerebral amyloid angiopathy in Alzheimer's disease.
Alzheimers Dement
; 16(10): 1372-1383, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32827351
11.
Elevated Neutrophil-Lymphocyte Ratio is Predictive of Poor Outcomes Following Aneurysmal Subarachnoid Hemorrhage.
J Stroke Cerebrovasc Dis
; 29(4): 104631, 2020 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-31964576
12.
APOE ε4/ε4 diminishes neurotrophic function of human iPSC-derived astrocytes.
Hum Mol Genet
; 26(14): 2690-2700, 2017 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28444230
13.
ApoE-2 Brain-Targeted Gene Therapy Through Transferrin and Penetratin Tagged Liposomal Nanoparticles.
Pharm Res
; 36(11): 161, 2019 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31529284
14.
5-HT3 Antagonist Ondansetron Increases apoE Secretion by Modulating the LXR-ABCA1 Pathway.
Int J Mol Sci
; 20(6)2019 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30934555
15.
Astrocytic LRP1 Mediates Brain Aß Clearance and Impacts Amyloid Deposition.
J Neurosci
; 37(15): 4023-4031, 2017 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28275161
16.
Identification of plexin A4 as a novel clusterin receptor links two Alzheimer's disease risk genes.
Hum Mol Genet
; 25(16): 3467-3475, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27378688
17.
Multiple system atrophy and apolipoprotein E.
Mov Disord
; 33(4): 647-650, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29442376
18.
ABCA7 Deficiency Accelerates Amyloid-ß Generation and Alzheimer's Neuronal Pathology.
J Neurosci
; 36(13): 3848-59, 2016 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27030769
19.
Role of LRP1 in the pathogenesis of Alzheimer's disease: evidence from clinical and preclinical studies.
J Lipid Res
; 58(7): 1267-1281, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28381441
20.
APOE2 eases cognitive decline during Aging: Clinical and preclinical evaluations.
Ann Neurol
; 79(5): 758-774, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26933942