Detalhe da pesquisa
1.
Trial of SAGE-217 in Patients with Major Depressive Disorder.
N Engl J Med
; 381(10): 903-911, 2019 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31483961
2.
A phase 1 double-blind, placebo-controlled study of zuranolone (SAGE-217) in a phase advance model of insomnia in healthy adults.
Hum Psychopharmacol
; 37(1): e2806, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34352138
3.
Associations between commonly used patient-reported outcome tools in postpartum depression clinical practice and the Hamilton Rating Scale for Depression.
Arch Womens Ment Health
; 23(5): 727-735, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32666402
4.
Brexanolone as adjunctive therapy in super-refractory status epilepticus.
Ann Neurol
; 82(3): 342-352, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28779545
5.
Trial of SAGE-217 in Patients with Major Depressive Disorder. Reply.
N Engl J Med
; 381(22): 2179, 2019 11 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31774969
6.
Open-label, proof-of-concept study of brexanolone in the treatment of severe postpartum depression.
Hum Psychopharmacol
; 32(2)2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28370307
7.
First Human Study of the Investigational Sedative and Anesthetic Drug AZD3043: A Dose-Escalation Trial to Assess the Safety, Pharmacokinetics, and Efficacy of a 30-Minute Infusion in Healthy Male Volunteers.
Anesth Analg
; 121(4): 885-893, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26111262
8.
A Bolus and Bolus Followed by Infusion Study of AZD3043, an Investigational Intravenous Drug for Sedation and Anesthesia: Safety and Pharmacodynamics in Healthy Male and Female Volunteers.
Anesth Analg
; 121(4): 894-903, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26097986
9.
The selective neurokinin 3 antagonist AZD2624 does not improve symptoms or cognition in schizophrenia: a proof-of-principle study.
J Clin Psychopharmacol
; 34(2): 199-204, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24525659
10.
Targeting the Arginine Vasopressin V1b Receptor System and Stress Response in Depression and Other Neuropsychiatric Disorders.
Neuropsychiatr Dis Treat
; 19: 811-828, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37077711
11.
Zuranolone in Major Depressive Disorder: Results From MOUNTAIN-A Phase 3, Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial.
J Clin Psychiatry
; 84(2)2023 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36811520
12.
Zuranolone for the Treatment of Adults With Major Depressive Disorder: A Randomized, Placebo-Controlled Phase 3 Trial.
Am J Psychiatry
; 180(9): 676-684, 2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37132201
13.
Effect of Zuranolone on Concurrent Anxiety and Insomnia Symptoms in Women With Postpartum Depression.
J Clin Psychiatry
; 84(1)2023 01 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36724109
14.
Effect of brexanolone on depressive symptoms, anxiety, and insomnia in women with postpartum depression: Pooled analyses from 3 double-blind, randomized, placebo-controlled clinical trials in the HUMMINGBIRD clinical program.
J Affect Disord
; 320: 353-359, 2023 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36191643
15.
Patient-reported health-related quality of life from a randomized, placebo-controlled phase 2 trial of zuranolone in adults with major depressive disorder.
J Affect Disord
; 308: 19-26, 2022 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35378149
16.
Zuranolone as an oral adjunct to treatment of Parkinsonian tremor: A phase 2, open-label study.
J Neurol Sci
; 421: 117277, 2021 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33387701
17.
Brexanolone in Postpartum Depression: Post Hoc Analyses to Help Inform Clinical Decision-Making.
J Womens Health (Larchmt)
; 30(3): 385-392, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33181049
18.
Effect of Zuranolone vs Placebo in Postpartum Depression: A Randomized Clinical Trial.
JAMA Psychiatry
; 78(9): 951-959, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34190962
19.
Achieving clinical response in postpartum depression leads to improvement in health-related quality of life.
Curr Med Res Opin
; 37(7): 1221-1231, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33719782
20.
Allopregnanolone in postpartum depression: Role in pathophysiology and treatment.
Neurobiol Stress
; 12: 100212, 2020 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-32435663