Detalhe da pesquisa
1.
Survival with Olaparib in Metastatic Castration-Resistant Prostate Cancer.
N Engl J Med
; 383(24): 2345-2357, 2020 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32955174
2.
Olaparib for Metastatic Castration-Resistant Prostate Cancer.
N Engl J Med
; 382(22): 2091-2102, 2020 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32343890
3.
Pain and health-related quality of life with olaparib versus physician's choice of next-generation hormonal drug in patients with metastatic castration-resistant prostate cancer with homologous recombination repair gene alterations (PROfound): an open-label, randomised, phase 3 trial.
Lancet Oncol
; 23(3): 393-405, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35157830
4.
Patient-reported outcomes with olaparib plus abiraterone versus placebo plus abiraterone for metastatic castration-resistant prostate cancer: a randomised, double-blind, phase 2 trial.
Lancet Oncol
; 23(10): 1297-1307, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36063830
5.
Olaparib for Metastatic Castration-Resistant Prostate Cancer. Reply.
N Engl J Med
; 383(9): 891, 2020 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32846073
6.
STAT3 stimulates adipogenic stem cell proliferation and cooperates with HMGA2 during the early stage of differentiation to promote adipogenesis.
Biochem Biophys Res Commun
; 482(4): 1360-1366, 2017 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27940362
7.
SARS-CoV-2 infection negatively impacts on the quality of embryos by delaying early embryonic development.
Am J Reprod Immunol
; 91(3): e13831, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38444103
8.
Olaparib for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer and Alterations in BRCA1 and/or BRCA2 in the PROfound Trial.
J Clin Oncol
; 42(5): 571-583, 2024 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37963304
9.
Impact of DNA damage repair alterations on prostate cancer progression and metastasis.
Front Oncol
; 13: 1162644, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37434977
10.
Hepatocytic AP-1 and STAT3 contribute to chemotaxis in alphanaphthylisothiocyanate-induced cholestatic liver injury.
Toxicol Lett
; 373: 184-193, 2023 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36460194
11.
Olaparib Efficacy in Patients with Metastatic Castration-resistant Prostate Cancer and BRCA1, BRCA2, or ATM Alterations Identified by Testing Circulating Tumor DNA.
Clin Cancer Res
; 29(1): 92-99, 2023 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36318705
12.
Promoter CAG is more efficient than hepatocytetargeting TBG for transgene expression via rAAV8 in liver tissues.
Mol Med Rep
; 25(1)2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34779500
13.
Tumor Genomic Testing for >4,000 Men with Metastatic Castration-resistant Prostate Cancer in the Phase III Trial PROfound (Olaparib).
Clin Cancer Res
; 28(8): 1518-1530, 2022 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35091440
14.
Abiraterone and Olaparib for Metastatic Castration-Resistant Prostate Cancer.
NEJM Evid
; 1(9): EVIDoa2200043, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-38319800
15.
Homologous Recombination Repair Gene Mutation Characterization by Liquid Biopsy: A Phase II Trial of Olaparib and Abiraterone in Metastatic Castrate-Resistant Prostate Cancer.
Cancers (Basel)
; 13(22)2021 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34830984
16.
Safety and Efficacy of Through-the-Scope Placement of Colonic Self-expandable Metal Stents Without Fluoroscopic Guidance: A Retrospective Cohort Study.
Surg Laparosc Endosc Percutan Tech
; 30(5): 430-434, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-32398445
17.
PPARα mediates night neon light-induced weight gain: role of lipid homeostasis.
Theranostics
; 10(25): 11497-11506, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33052228
18.
Re: Konrad H. Stopsack. Efficacy of PARP Inhibition in Metastatic Castration-resistant Prostate Cancer is Very Different with Non-BRCA DNA Repair Alterations: Reconstructing Prespecified Endpoints for Cohort B from the Phase 3 PROfound Trial of Olaparib. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2020.09.024.
Eur Urol
; 79(3): e83-e84, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33358234
19.
Interferon-alpha differentially affects homeostasis of human plasmacytoid and myeloid dendritic cells.
J Interferon Cytokine Res
; 29(3): 145-60, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19196069
20.
Altered chemotactic response of myeloid and plasmacytoid dendritic cells from patients with chronic hepatitis C: role of alpha interferon.
J Gen Virol
; 89(Pt 5): 1243-1253, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18420803