Detalhe da pesquisa
1.
Manganese and Vanadium Co-Exposure Induces Severe Neurotoxicity in the Olfactory System: Relevance to Metal-Induced Parkinsonism.
Int J Mol Sci
; 25(10)2024 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38791326
2.
High-Yield α-Synuclein Purification and Ionic Strength Modification Pivotal to Seed Amplification Assay Performance and Reproducibility.
Int J Mol Sci
; 25(11)2024 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38892177
3.
Impact of Environmental Risk Factors on Mitochondrial Dysfunction, Neuroinflammation, Protein Misfolding, and Oxidative Stress in the Etiopathogenesis of Parkinson's Disease.
Int J Mol Sci
; 23(18)2022 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36142718
4.
α-Synuclein real-time quaking-induced conversion in the submandibular glands of Parkinson's disease patients.
Mov Disord
; 35(2): 268-278, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31758740
5.
Blinded RT-QuIC Analysis of α-Synuclein Biomarker in Skin Tissue From Parkinson's Disease Patients.
Mov Disord
; 35(12): 2230-2239, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32960470
6.
Prokineticin-2 promotes chemotaxis and alternative A2 reactivity of astrocytes.
Glia
; 66(10): 2137-2157, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30277602
7.
Organophosphate pesticide chlorpyrifos impairs STAT1 signaling to induce dopaminergic neurotoxicity: Implications for mitochondria mediated oxidative stress signaling events.
Neurobiol Dis
; 117: 82-113, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29859868
8.
Molecular mechanisms underlying protective effects of quercetin against mitochondrial dysfunction and progressive dopaminergic neurodegeneration in cell culture and MitoPark transgenic mouse models of Parkinson's Disease.
J Neurochem
; 141(5): 766-782, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28376279
9.
Fyn Kinase Regulates Microglial Neuroinflammatory Responses in Cell Culture and Animal Models of Parkinson's Disease.
J Neurosci
; 35(27): 10058-77, 2015 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26157004
10.
Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease.
Neurobiol Dis
; 93: 96-114, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27151770
11.
Histone hyperacetylation up-regulates protein kinase Cδ in dopaminergic neurons to induce cell death: relevance to epigenetic mechanisms of neurodegeneration in Parkinson disease.
J Biol Chem
; 289(50): 34743-67, 2014 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25342743
12.
Mitochondria-targeted antioxidants for treatment of Parkinson's disease: preclinical and clinical outcomes.
Biochim Biophys Acta
; 1842(8): 1282-94, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24060637
13.
Molecular cloning, epigenetic regulation, and functional characterization of Prkd1 gene promoter in dopaminergic cell culture models of Parkinson's disease.
J Neurochem
; 135(2): 402-15, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26230914
14.
The peptidyl-prolyl isomerase Pin1 up-regulation and proapoptotic function in dopaminergic neurons: relevance to the pathogenesis of Parkinson disease.
J Biol Chem
; 288(30): 21955-71, 2013 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23754278
15.
Mito-metformin protects against mitochondrial dysfunction and dopaminergic neuronal degeneration by activating upstream PKD1 signaling in cell culture and MitoPark animal models of Parkinson's disease.
Front Neurosci
; 18: 1356703, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38449738
16.
Epitranscriptomic Reader YTHDF2 Regulates SEK1( MAP2K4 )-JNK-cJUN Inflammatory Signaling in Astrocytes during Neurotoxic Stress.
bioRxiv
; 2024 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38328119
17.
Microglial immune regulation by epigenetic reprogramming through histone H3K27 acetylation in neuroinflammation.
Front Immunol
; 14: 1052925, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37033967
18.
α-Synuclein negatively regulates protein kinase Cδ expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activity.
J Neurosci
; 31(6): 2035-51, 2011 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-21307242
19.
Transcriptional regulation of pro-apoptotic protein kinase Cdelta: implications for oxidative stress-induced neuronal cell death.
J Biol Chem
; 286(22): 19840-59, 2011 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-21467032
20.
Proteolytic activation of proapoptotic kinase protein kinase Cδ by tumor necrosis factor α death receptor signaling in dopaminergic neurons during neuroinflammation.
J Neuroinflammation
; 9: 82, 2012 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22540228