Detalhe da pesquisa
1.
Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches.
Cell
; 185(2): 379-396.e38, 2022 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35021063
2.
Blocking NS3-NS4B interaction inhibits dengue virus in non-human primates.
Nature
; 615(7953): 678-686, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36922586
3.
A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction.
Nature
; 598(7881): 504-509, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34616043
4.
A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate.
Nature
; 590(7845): 320-325, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33260195
5.
Animal models for COVID-19.
Nature
; 586(7830): 509-515, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32967005
6.
Perturbation of Alphavirus and Flavivirus Infectivity by Components of the Bacterial Cell Wall.
J Virol
; 96(6): e0006022, 2022 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35107376
7.
A SCID Mouse Model To Evaluate the Efficacy of Antivirals against SARS-CoV-2 Infection.
J Virol
; 96(16): e0075822, 2022 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35924921
8.
Favipiravir at high doses has potent antiviral activity in SARS-CoV-2-infected hamsters, whereas hydroxychloroquine lacks activity.
Proc Natl Acad Sci U S A
; 117(43): 26955-26965, 2020 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33037151
9.
Publisher Correction: A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction.
Nature
; 599(7883): E2, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34671169
10.
A Viral Polymerase Inhibitor Reduces Zika Virus Replication in the Reproductive Organs of Male Mice.
Int J Mol Sci
; 20(9)2019 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31032814
11.
Design, synthesis, optimization and antiviral activity of a class of hybrid dengue virus E protein inhibitors.
Bioorg Med Chem Lett
; 25(8): 1747-1752, 2015 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25791449
12.
Multiplexed multicolor antiviral assay amenable for high-throughput research.
Nat Commun
; 15(1): 42, 2024 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38168091
13.
Discovery of JNJ-1802, a First-in-Class Pan-Serotype Dengue Virus NS4B Inhibitor.
J Med Chem
; 67(5): 4063-4082, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38482827
14.
Establishment of a robust rat hepatitis E virus fecal-oral infection model and validation for antiviral studies.
Antiviral Res
; 216: 105670, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37451630
15.
Discovery of Acyl-Indole Derivatives as Pan-Serotype Dengue Virus NS4B Inhibitors.
J Med Chem
; 66(13): 8808-8821, 2023 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37389813
16.
Expanded profiling of Remdesivir as a broad-spectrum antiviral and low potential for interaction with other medications in vitro.
Sci Rep
; 13(1): 3131, 2023 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36823196
17.
Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug.
J Antimicrob Chemother
; 67(8): 1884-94, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22535622
18.
Use of Micro-Computed Tomography to Visualize and Quantify COVID-19 Vaccine Efficiency in Free-Breathing Hamsters.
Methods Mol Biol
; 2410: 177-192, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34914047
19.
HIV protease inhibitors Nelfinavir and Lopinavir/Ritonavir markedly improve lung pathology in SARS-CoV-2-infected Syrian hamsters despite lack of an antiviral effect.
Antiviral Res
; 202: 105311, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35390430
20.
Comparing infectivity and virulence of emerging SARS-CoV-2 variants in Syrian hamsters.
EBioMedicine
; 68: 103403, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-34049240