Pesquisa | Portal de Pesquisa da BVS

1.

Syntaxin 5 determines Weibel-Palade body size and von Willebrand factor secretion by controlling Golgi architecture.

Kat, Marije; Karampini, Ellie; Hoogendijk, Arie J; Bürgisser, Petra E; Mulder, Aat A; Van Alphen, Floris P J; Olins, Jenny; Geerts, Dirk; Van den Biggelaar, Maartje; Margadant, Coert; Voorberg, Jan; Bierings, Ruben.

Haematologica ; 107(8): 1827-1839, 2022 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-35081689

2.

Von Willebrand factor propeptide in severe coronavirus disease 2019 (COVID-19): evidence of acute and sustained endothelial cell activation.

Ward, Soracha E; Curley, Gerard F; Lavin, Michelle; Fogarty, Helen; Karampini, Ellie; McEvoy, Natalie L; Clarke, Jennifer; Boylan, Maria; Alalqam, Razi; Worrall, Amy P; Kelly, Claire; de Barra, Eoghan; Glavey, Siobhan; Ni Cheallaigh, Cliona; Bergin, Colm; Martin-Loeches, Ignacio; Townsend, Liam; Mallon, Patrick W; O'Sullivan, Jamie M; O'Donnell, James S.

Br J Haematol ; 192(4): 714-719, 2021 02.

Artigo em Inglês | MEDLINE | ID: mdl-33326604

3.

Sec22b determines Weibel-Palade body length by controlling anterograde ER-Golgi transport.

Karampini, Ellie; Bürgisser, Petra E; Olins, Jenny; Mulder, Aat A; Jost, Carolina R; Geerts, Dirk; Voorberg, Jan; Bierings, Ruben.

Haematologica ; 106(4): 1138-1147, 2021 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-32336681

4.

Orchestration of Primary Hemostasis by Platelet and Endothelial Lysosome-Related Organelles.

Karampini, Ellie; Bierings, Ruben; Voorberg, Jan.

Arterioscler Thromb Vasc Biol ; 40(6): 1441-1453, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-32375545

5.

Defective AP-3-dependent VAMP8 trafficking impairs Weibel-Palade body exocytosis in Hermansky-Pudlak Syndrome type 2 blood outgrowth endothelial cells.

Karampini, Ellie; Schillemans, Maaike; Hofman, Menno; van Alphen, Floris; de Boer, Martin; Kuijpers, Taco W; van den Biggelaar, Maartje; Voorberg, Jan; Bierings, Ruben.

Haematologica ; 104(10): 2091-2099, 2019 10.

Artigo em Inglês | MEDLINE | ID: mdl-30630984

6.

Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells.

Schillemans, Maaike; Karampini, Ellie; van den Eshof, Bart L; Gangaev, Anastasia; Hofman, Menno; van Breevoort, Dorothee; Meems, Henriët; Janssen, Hans; Mulder, Aat A; Jost, Carolina R; Escher, Johanna C; Adam, Rüdiger; Carter, Tom; Koster, Abraham J; van den Biggelaar, Maartje; Voorberg, Jan; Bierings, Ruben.

Arterioscler Thromb Vasc Biol ; 38(7): 1549-1561, 2018 07.

Artigo em Inglês | MEDLINE | ID: mdl-29880488

7.

New kid on the BLOC.

Karampini, Ellie; Voorberg, Jan.

Blood ; 136(24): 2729-2730, 2020 12 10.

Artigo em Inglês | MEDLINE | ID: mdl-33301034

8.

O-glycan determinants regulate VWF trafficking to Weibel-Palade bodies.

Karampini, Ellie; Doherty, Dearbhla; Bürgisser, Petra E; Garre, Massimiliano; Schoen, Ingmar; Elliott, Stephanie; Bierings, Ruben; O'Donnell, James S.

Blood Adv ; 2024 Apr 19.

Artigo em Inglês | MEDLINE | ID: mdl-38640438

9.

VWF-ADAMTS13 axis dysfunction in children with sickle cell disease treated with hydroxycarbamide vs blood transfusion.

Fogarty, Helen; Ahmad, Azaz; Atiq, Ferdows; Doherty, Dearbhla; Ward, Soracha; Karampini, Ellie; Rehill, Aisling; Leon, Gemma; Byrne, Ciara; Geoghegan, Rosena; Conroy, Helena; Byrne, Mary; Budde, Ulrich; Schneppenheim, Sonja; Sheehan, Ciara; Ngwenya, Noel; Baker, Ross I; Preston, Roger J S; Tuohy, Emma; McMahon, Corrina; O'Donnell, James S.

Blood Adv ; 7(22): 6974-6989, 2023 11 28.

Artigo em Inglês | MEDLINE | ID: mdl-37773926

10.

Endothelial cell activation, Weibel-Palade body secretion, and enhanced angiogenesis in severe COVID-19.

Karampini, Ellie; Fogarty, Helen; Elliott, Stephanie; Morrin, Hannah; Bergin, Colm; O'Sullivan, Jamie M; Byrne, Mary; Martin-Loeches, Ignacio; Mallon, Patrick W; Curley, Gerard F; Glavey, Siobhan; Baker, Ross I; Lavin, M; Preston, Roger J S; Cheallaigh, Cliona Ni; Ward, Soracha E; O'Donnell, James S.

Res Pract Thromb Haemost ; 7(2): 100085, 2023 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-36817284

11.

Sustained VWF-ADAMTS-13 axis imbalance and endotheliopathy in long COVID syndrome is related to immune dysfunction.

Fogarty, Helen; Ward, Soracha E; Townsend, Liam; Karampini, Ellie; Elliott, Stephanie; Conlon, Niall; Dunne, Jean; Kiersey, Rachel; Naughton, Aifric; Gardiner, Mary; Byrne, Mary; Bergin, Colm; O'Sullivan, Jamie M; Martin-Loeches, Ignacio; Nadarajan, Parthiban; Bannan, Ciaran; Mallon, Patrick W; Curley, Gerard F; Preston, Roger J S; Rehill, Aisling M; Baker, Ross I; Cheallaigh, Cliona Ni; O'Donnell, James S.

J Thromb Haemost ; 20(10): 2429-2438, 2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-35875995

12.

Generation and characterization of a control and patient-derived human iPSC line containing the Hermansky Pudlak type 2 (HPS2) associated heterozygous compound mutation in AP3B1.

Aarts, Cathelijn E M; Karampini, Ellie; Wüst, Tatjana; Webbers, Steven; Varga, Eszter; Geissler, Judy; Voorberg, Jan; von Lindern, Marieke; Bierings, Ruben; van den Akker, Emile; Kuijpers, Taco W.

Stem Cell Res ; 54: 102444, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-34182253

13.

ADAMTS13 regulation of VWF multimer distribution in severe COVID-19.

Ward, Soracha E; Fogarty, Helen; Karampini, Ellie; Lavin, Michelle; Schneppenheim, Sonja; Dittmer, Rita; Morrin, Hannah; Glavey, Siobhan; Ni Cheallaigh, Cliona; Bergin, Colm; Martin-Loeches, Ignacio; Mallon, Patrick W; Curley, Gerard F; Baker, Ross I; Budde, Ulrich; O'Sullivan, Jamie M; O'Donnell, James S.

J Thromb Haemost ; 19(8): 1914-1921, 2021 08.

Artigo em Inglês | MEDLINE | ID: mdl-34053187

14.

Persistent endotheliopathy in the pathogenesis of long COVID syndrome.

Fogarty, Helen; Townsend, Liam; Morrin, Hannah; Ahmad, Azaz; Comerford, Claire; Karampini, Ellie; Englert, Hanna; Byrne, Mary; Bergin, Colm; O'Sullivan, Jamie M; Martin-Loeches, Ignacio; Nadarajan, Parthiban; Bannan, Ciaran; Mallon, Patrick W; Curley, Gerard F; Preston, Roger J S; Rehill, Aisling M; McGonagle, Dennis; Ni Cheallaigh, Cliona; Baker, Ross I; Renné, Thomas; Ward, Soracha E; O'Donnell, James S.

J Thromb Haemost ; 19(10): 2546-2553, 2021 10.

Artigo em Inglês | MEDLINE | ID: mdl-34375505

15.

Interaction networks of Weibel-Palade body regulators syntaxin-3 and syntaxin binding protein 5 in endothelial cells.

Schillemans, Maaike; Karampini, Ellie; Hoogendijk, Arie J; Wahedi, Maryam; van Alphen, Floris P J; van den Biggelaar, Maartje; Voorberg, Jan; Bierings, Ruben.

J Proteomics ; 205: 103417, 2019 08 15.

Artigo em Inglês | MEDLINE | ID: mdl-31201948

16.

Elevated von Willebrand factor levels in multiple myeloma: dysregulated mechanisms of both secretion and clearance.

Comerford, Claire; Dhami, Sukhraj Pal Singh; Murphy, Philip; Patmore, Sean; Ward, Soracha; Pushkar, Nadiya; Budde, Ulrich; Karampini, Ellie; O'Donnell, James S; Glavey, Siobhan; Quinn, John; O'Sullivan, Jamie M.

Thromb Res ; 226: 136-140, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-37150027

17.

Persistent endotheliopathy in the pathogenesis of long COVID syndrome - Reply to comment from von Meijenfeldt et al.

Fogarty, Helen; Karampini, Ellie; O'Donnell, Andrew S; Ward, Soracha E; O'Sullivan, Jamie M; O'Donnell, James S.

J Thromb Haemost ; 20(1): 270-271, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-34738307

18.

Correcting dominant-negative von Willebrand disease.

Karampini, Ellie; O'Donnell, James S.

J Thromb Haemost ; 19(1): 55-57, 2021 01.

Artigo em Inglês | MEDLINE | ID: mdl-33405380

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