Detalhe da pesquisa
1.
A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study.
Lancet
; 401(10374): 347-356, 2023 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36739136
2.
Properties of the full random-effect modeling approach with missing covariate data.
Stat Med
; 43(5): 935-952, 2024 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38128126
3.
Characterization of anti-drug antibody dynamics using a bivariate mixed hidden-markov model by nonlinear-mixed effects approach.
J Pharmacokinet Pharmacodyn
; 51(1): 65-75, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37943398
4.
Training the next generation of pharmacometric modelers: a multisector perspective.
J Pharmacokinet Pharmacodyn
; 51(1): 5-31, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37573528
5.
Generation and application of avatars in pharmacometric modelling.
J Pharmacokinet Pharmacodyn
; 50(5): 411-423, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37488327
6.
Joint longitudinal model-based meta-analysis of FEV1 and exacerbation rate in randomized COPD trials.
J Pharmacokinet Pharmacodyn
; 50(4): 297-314, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36947282
7.
Population Pharmacokinetic and Concentration-QTc Analysis of Delamanid in Pediatric Participants with Multidrug-Resistant Tuberculosis.
Antimicrob Agents Chemother
; 66(2): e0160821, 2022 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34843388
8.
Ceftriaxone dosing based on the predicted probability of augmented renal clearance in critically ill patients with pneumonia.
J Antimicrob Chemother
; 77(9): 2479-2488, 2022 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35815604
9.
Improved Confidence in a Confirmatory Stage by Application of Item-Based Pharmacometrics Model: Illustration with a Phase III Active Comparator-Controlled Trial in COPD Patients.
Pharm Res
; 39(8): 1779-1787, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35233731
10.
Pharmacokinetics and safety of high-dose rifampicin in children with TB: the Opti-Rif trial.
J Antimicrob Chemother
; 76(12): 3237-3246, 2021 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34529779
11.
Pharmacometrics-Based Considerations for the Design of a Pharmacogenomic Clinical Trial Assessing Irinotecan Safety.
Pharm Res
; 38(4): 593-605, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33733372
12.
Improved numerical stability for the bounded integer model.
J Pharmacokinet Pharmacodyn
; 48(2): 241-251, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33242184
13.
A general model for cell death and biomarker release from injured tissues.
J Pharmacokinet Pharmacodyn
; 48(1): 69-82, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32996046
14.
Generating evidence for precision medicine: considerations made by the Ubiquitous Pharmacogenomics Consortium when designing and operationalizing the PREPARE study.
Pharmacogenet Genomics
; 30(6): 131-144, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32317559
15.
The effect of food on the pharmacokinetics of oral ivermectin.
J Antimicrob Chemother
; 75(2): 438-440, 2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31691813
16.
Relationship between factor VIII activity, bleeds and individual characteristics in severe hemophilia A patients.
Haematologica
; 105(5): 1443-1453, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31371418
17.
Understanding the drug exposure-response relationship of bedaquiline to predict efficacy for novel dosing regimens in the treatment of multidrug-resistant tuberculosis.
Br J Clin Pharmacol
; 86(5): 913-922, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31840278
18.
Comparison of covariate selection methods with correlated covariates: prior information versus data information, or a mixture of both?
J Pharmacokinet Pharmacodyn
; 47(5): 485-492, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32661654
19.
A longitudinal item response model for Aberrant Behavior Checklist (ABC) data from children with autism.
J Pharmacokinet Pharmacodyn
; 47(3): 241-253, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32285302
20.
Performance of longitudinal item response theory models in shortened or partial assessments.
J Pharmacokinet Pharmacodyn
; 47(5): 461-471, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32617833