Detalhe da pesquisa
1.
Impaired TRPV4-eNOS signaling in trabecular meshwork elevates intraocular pressure in glaucoma.
Proc Natl Acad Sci U S A
; 118(16)2021 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33853948
2.
Caveolar peroxynitrite formation impairs endothelial TRPV4 channels and elevates pulmonary arterial pressure in pulmonary hypertension.
Proc Natl Acad Sci U S A
; 118(17)2021 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33879616
3.
A Novel Mouse Model of TGFß2-Induced Ocular Hypertension Using Lentiviral Gene Delivery.
Int J Mol Sci
; 23(13)2022 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35805889
4.
Sodium 4-Phenylbutyrate Reduces Ocular Hypertension by Degrading Extracellular Matrix Deposition via Activation of MMP9.
Int J Mol Sci
; 22(18)2021 Sep 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34576258
5.
Astragaloside IV Attenuates Ocular Hypertension in a Mouse Model of TGFß2 Induced Primary Open Angle Glaucoma.
Int J Mol Sci
; 22(22)2021 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34830390
6.
Mechanisms underlying selective coupling of endothelial Ca2+ signals with eNOS vs. IK/SK channels in systemic and pulmonary arteries.
J Physiol
; 598(17): 3577-3596, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32463112
7.
Technical brief: Direct, real-time electrochemical measurement of nitric oxide in ex vivo cultured human corneoscleral segments.
Mol Vis
; 26: 434-444, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32565671
8.
CRISPR-Cas9-based treatment of myocilin-associated glaucoma.
Proc Natl Acad Sci U S A
; 114(42): 11199-11204, 2017 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28973933
9.
Transforming growth factor ß2 (TGFß2) signaling plays a key role in glucocorticoid-induced ocular hypertension.
J Biol Chem
; 293(25): 9854-9868, 2018 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29743238
10.
Dexamethasone-Induced Ocular Hypertension in Mice: Effects of Myocilin and Route of Administration.
Am J Pathol
; 187(4): 713-723, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28167045
11.
Autophagy stimulation reduces ocular hypertension in a murine glaucoma model via autophagic degradation of mutant myocilin.
JCI Insight
; 6(5)2021 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33539326
12.
Correction: Ex-vivo cultured human corneoscleral segment model to study the effects of glaucoma factors on trabecular meshwork.
PLoS One
; 15(8): e0238408, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32841305
13.
Ex-vivo cultured human corneoscleral segment model to study the effects of glaucoma factors on trabecular meshwork.
PLoS One
; 15(6): e0232111, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32579557
14.
CNS axonal degeneration and transport deficits at the optic nerve head precede structural and functional loss of retinal ganglion cells in a mouse model of glaucoma.
Mol Neurodegener
; 15(1): 48, 2020 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32854767
15.
ATF4 leads to glaucoma by promoting protein synthesis and ER client protein load.
Nat Commun
; 11(1): 5594, 2020 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33154371
16.
Zika Virus Infects Trabecular Meshwork and Causes Trabeculitis and Glaucomatous Pathology in Mouse Eyes.
mSphere
; 4(3)2019 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31068433
17.
Methods for Analyzing Endoplasmic Reticulum Stress in the Trabecular Meshwork of Glaucoma Models.
Methods Mol Biol
; 1695: 121-134, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29190024
18.
Increased synthesis and deposition of extracellular matrix proteins leads to endoplasmic reticulum stress in the trabecular meshwork.
Sci Rep
; 7(1): 14951, 2017 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29097767
19.
Expression of Mutant Myocilin Induces Abnormal Intracellular Accumulation of Selected Extracellular Matrix Proteins in the Trabecular Meshwork.
Invest Ophthalmol Vis Sci
; 57(14): 6058-6069, 2016 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27820874
20.
14-3-3σ regulates keratinocyte proliferation and differentiation by modulating Yap1 cellular localization.
J Invest Dermatol
; 135(6): 1621-1628, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25668240