Detalhe da pesquisa
1.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature
; 569(7757): 503-508, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31068700
2.
Fully unsupervised deep mode of action learning for phenotyping high-content cellular images.
Bioinformatics
; 37(23): 4548-4555, 2021 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34240099
3.
Contribution and clinical relevance of germline variation to the cancer transcriptome.
BMC Cancer
; 22(1): 675, 2022 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35725412
4.
Resistance mechanisms to TP53-MDM2 inhibition identified by in vivo piggyBac transposon mutagenesis screen in an Arf-/- mouse model.
Proc Natl Acad Sci U S A
; 114(12): 3151-3156, 2017 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28265066
5.
Correction of copy number induced false positives in CRISPR screens.
PLoS Comput Biol
; 14(7): e1006279, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30024886
6.
Ten simple rules to power drug discovery with data science.
PLoS Comput Biol
; 16(8): e1008126, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32853229
7.
Gene expression signature predicting high-grade prostate cancer responses to oxaliplatin.
Mol Pharmacol
; 82(6): 1205-16, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22986617
8.
Exquisite Sensitivity to Dual BRG1/BRM ATPase Inhibitors Reveals Broad SWI/SNF Dependencies in Acute Myeloid Leukemia.
Mol Cancer Res
; 20(3): 361-372, 2022 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34799403
9.
Microarray data quality control improves the detection of differentially expressed genes.
Genomics
; 95(3): 138-42, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20079422
10.
Systematic dissection of transcriptional regulatory networks by genome-scale and single-cell CRISPR screens.
Sci Adv
; 7(27)2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34215580
11.
arrayQualityMetrics--a bioconductor package for quality assessment of microarray data.
Bioinformatics
; 25(3): 415-6, 2009 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19106121
12.
Importing ArrayExpress datasets into R/Bioconductor.
Bioinformatics
; 25(16): 2092-4, 2009 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19505942
13.
Genetic heterogeneity and clonal evolution during metastasis in breast cancer patient-derived tumor xenograft models.
Comput Struct Biotechnol J
; 18: 323-331, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32099592
14.
The Discovery of SWI/SNF Chromatin Remodeling Activity as a Novel and Targetable Dependency in Uveal Melanoma.
Mol Cancer Ther
; 19(10): 2186-2195, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32747420
15.
PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma.
Nat Commun
; 10(1): 3739, 2019 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31431624
16.
FGF401, A First-In-Class Highly Selective and Potent FGFR4 Inhibitor for the Treatment of FGF19-Driven Hepatocellular Cancer.
Mol Cancer Ther
; 18(12): 2194-2206, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31409633
17.
Overexpression of DNA repair genes is associated with metastasis: a new hypothesis.
Mutat Res
; 659(1-2): 49-55, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18308619
18.
Dose and Schedule Determine Distinct Molecular Mechanisms Underlying the Efficacy of the p53-MDM2 Inhibitor HDM201.
Cancer Res
; 78(21): 6257-6267, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30135191
19.
Maximizing the Efficacy of MAPK-Targeted Treatment in PTENLOF/BRAFMUT Melanoma through PI3K and IGF1R Inhibition.
Cancer Res
; 76(2): 390-402, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26577700
20.
CRISPR Screens Provide a Comprehensive Assessment of Cancer Vulnerabilities but Generate False-Positive Hits for Highly Amplified Genomic Regions.
Cancer Discov
; 6(8): 900-13, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27260157