[Surgical treatment patients with drug-resistant unilateral MRI-positive temporal forms of epilepsy]. / Khirurgicheskoe lechenie patsientov s farmakorezistentnymi MR-pozitivnymi simptomaticheskimi odnostoronnimi visochnymi formami épilepsii.

AIM: To evaluate the results of surgical treatment of patients with unilateral MRI-positive temporal forms of drug-resistant epilepsy. MATERIAL AND METHODS: A prospective analysis of 50 patients with unilateral MRI-positive temporal forms of drug-resistant epilepsy, who had undergone resective surgery in the Scientific Research Institute of Emergency Medicine of N.V. Sklifosovsky (Moscow) and in University Clinic of Moscow State University of Medicine and Dentistry between 01.01.14 and 12.12.17, has been performed. MRI-positive temporal symptomatic epilepsy was identified in 79 (55%) patients. MRI results showed unilateral temporal epileptogenic lesions in 50 (67%) patients. These patients were assigned to medial frontal lobectomy. RESULTS: 82% patients become 'seizure free' 12 and 24 months after surgical treatment. In other cases, seizures become less frequent and severe. CONCLUSION: The results confirm the efficacy and safety of surgical treatment of drug-resistant MRI-positive temporal forms of epilepsy.

[Prognosis for surgical treatment of pharmacoresistant epilepsy: the role of mental and cognitive disorders]. / Prognoz khirurgicheskogo lecheniia farmakorezistentnoi épilepsii: rol' psikhicheskikh i kognitivnykh rasstroistv.

This review focuses on the role of mental and cognitive disorders in the prognosis for surgical treatment of pharmacoresistant epilepsy. The authors analyze historical aspects of the surgical treatment of epilepsy and present current data on the prognosis of operative intervention with respect to seizure control, cognitive functioning, and psychiatric disorders. The psychiatrist's role in the structure of preoperative and postoperative management of patients is considered.

[Cognitive impairment. The effects of seizures?] / Kognitivnye narusheniia - posledstviia sudorozhnogo pristupa?

This review discusses articles on cognitive impairments developing after one or more convulsive seizures. Cognitive disorders seem to be frequent complications of epilepsy. According to recent clinical studies, the intensity of cognitive declines depends on a frequency and severity of seizures. However, presence of an epileptic focus does not always indicate an increase in cognitive impairments. An effect of a single convulsive seizure on cognitive functions at this stage is uncertain. According to some data, cognitive impairments after a single generalized seizures develop only in specific clinical syndromes, on the other hand, they are influenced by the emotional state of the subject. This problem remains relevant today. Further work is needed in this direction.