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1.
Risk Anal ; 41(11): 2016-2030, 2021 11.
Artigo em Inglês | MEDLINE | ID: mdl-33580509

RESUMO

Infectious diseases pose a serious threat to humans. Therefore, it is crucial to understand how accurately people perceive these risks. However, accuracy can be operationalized differently depending on the standard of comparison. The present study investigated accuracy in risk perceptions for three infectious diseases (avian influenza, seasonal influenza, common cold) using three different standards for accuracy: Social comparison (self vs. others' risk perceptions), general problem level (risk perceptions for diseases with varying threat levels), and dynamic problem level (risk perceptions during epidemics/seasons vs. nonepidemic/off-season times). Four online surveys were conducted using a repeated cross-sectional design. Two surveys were conducted during epidemics/seasons of avian influenza, seasonal influenza, and common cold in 2006 (n = 387) and 2016 (n = 370) and two surveys during nonepidemic/off-season times for the three diseases in 2009 (n = 792) during a swine flu outbreak and in 2018 (n = 422) during no outbreak of zoonotic influenza. While on average participants felt less at risk than others, indicating an optimistic bias, risk perceptions matched the magnitude of risk associated with the three infectious diseases. Importantly, a significant three-way interaction indicated dynamic accuracy in risk perceptions: Participants felt more at risk for seasonal influenza and common cold during influenza and cold seasons, compared with off-season times. However, these dynamic increases were more pronounced in the perceived risk for others than for oneself (optimistic bias). The results emphasize the importance of using multiple approaches to assess accuracy of risk perception as they provided different information on how accurately people gauge their risk when facing infectious diseases.


Assuntos
Influenza Aviária/epidemiologia , Influenza Humana/epidemiologia , Infecções por Orthomyxoviridae/epidemiologia , Animais , Aves , Estudos Transversais , Humanos , Risco , Estações do Ano
2.
Int J Mol Sci ; 22(15)2021 Jul 30.
Artigo em Inglês | MEDLINE | ID: mdl-34361005

RESUMO

Although the development of gene delivery systems based on non-viral vectors is advancing, it remains a challenge to deliver plasmid DNA into human blood cells. The current "gold standard", namely linear polyethyleneimine (l-PEI 25 kDa), in particular, is unable to produce transgene expression levels >5% in primary human B lymphocytes. Here, it is demonstrated that a well-defined 24-armed poly(2-dimethylamino) ethyl methacrylate (PDMAEMA, 755 kDa) nano-star is able to reproducibly elicit high transgene expression (40%) at sufficient residual viability (69%) in primary human B cells derived from tonsillar tissue. Moreover, our results indicate that the length of the mitogenic stimulation prior to transfection is an important parameter that must be established during the development of the transfection protocol. In our hands, four days of stimulation with rhCD40L post-thawing led to the best transfection results in terms of TE and cell survival. Most importantly, our data argue for an impact of the B cell subsets on the transfection outcomes, underlining that the complexity and heterogeneity of a given B cell population pre- and post-transfection is a critical parameter to consider in the multiparametric approach required for the implementation of the transfection protocol.


Assuntos
Linfócitos B/metabolismo , Técnicas de Transferência de Genes , Vetores Genéticos/genética , Linfócitos B/citologia , Células Cultivadas , Humanos , Metacrilatos/química , Nylons/química , Transgenes
3.
Sensors (Basel) ; 20(18)2020 Sep 22.
Artigo em Inglês | MEDLINE | ID: mdl-32971822

RESUMO

The technical progress in the last decades makes photo and video recording devices omnipresent. This change has a significant impact, among others, on police work. It is no longer unusual that a myriad of digital data accumulates after a criminal act, which must be reviewed by criminal investigators to collect evidence or solve the crime. This paper presents the VICTORIA Interactive 4D Scene Reconstruction and Analysis Framework ("ISRA-4D" 1.0), an approach for the visual consolidation of heterogeneous video and image data in a 3D reconstruction of the corresponding environment. First, by reconstructing the environment in which the materials were created, a shared spatial context of all available materials is established. Second, all footage is spatially and temporally registered within this 3D reconstruction. Third, a visualization of the hereby created 4D reconstruction (3D scene + time) is provided, which can be analyzed interactively. Additional information on video and image content is also extracted and displayed and can be analyzed with supporting visualizations. The presented approach facilitates the process of filtering, annotating, analyzing, and getting an overview of large amounts of multimedia material. The framework is evaluated using four case studies which demonstrate its broad applicability. Furthermore, the framework allows the user to immerse themselves in the analysis by entering the scenario in virtual reality. This feature is qualitatively evaluated by means of interviews of criminal investigators and outlines potential benefits such as improved spatial understanding and the initiation of new fields of application.

4.
J Sports Sci ; 37(24): 2774-2782, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31402759

RESUMO

To prepare their teams for upcoming matches, analysts in professional soccer watch and manually annotate up to three matches a day. When annotating matches, domain experts try to identify and improve suboptimal movements based on intuition and professional experience. The high amount of matches needing to be analysed manually result in a tedious and time-consuming process, and results may be subjective. We propose an automatic approach for the realisation of effective region-based what-if analyses in soccer. Our system covers the automatic detection of region-based faulty movement behaviour, as well as the automatic suggestion of possible improved alternative movements. As we show, our approach effectively supports analysts and coaches investigating matches by speeding up previously time-consuming work. We enable domain experts to include their domain knowledge in the analysis process by allowing to interactively adjust suggested improved movement, as well as its implications on region control. We demonstrate the usefulness of our proposed approach via an expert study with three invited domain experts, one being head coach from the first Austrian soccer league. As our results show that experts most often agree with the suggested player movement (83%), our proposed approach enhances the analytical capabilities in soccer and supports a more efficient analysis.


Assuntos
Movimento , Reconhecimento Automatizado de Padrão , Futebol , Análise e Desempenho de Tarefas , Humanos
5.
BMC Genomics ; 18(1): 216, 2017 02 28.
Artigo em Inglês | MEDLINE | ID: mdl-28245801

RESUMO

BACKGROUND: While NGS allows rapid global detection of transcripts, it remains difficult to distinguish ncRNAs from short mRNAs. To detect potentially translated RNAs, we developed an improved protocol for bacterial ribosomal footprinting (RIBOseq). This allowed distinguishing ncRNA from mRNA in EHEC. A high ratio of ribosomal footprints per transcript (ribosomal coverage value, RCV) is expected to indicate a translated RNA, while a low RCV should point to a non-translated RNA. RESULTS: Based on their low RCV, 150 novel non-translated EHEC transcripts were identified as putative ncRNAs, representing both antisense and intergenic transcripts, 74 of which had expressed homologs in E. coli MG1655. Bioinformatics analysis predicted statistically significant target regulons for 15 of the intergenic transcripts; experimental analysis revealed 4-fold or higher differential expression of 46 novel ncRNA in different growth media. Out of 329 annotated EHEC ncRNAs, 52 showed an RCV similar to protein-coding genes, of those, 16 had RIBOseq patterns matching annotated genes in other enterobacteriaceae, and 11 seem to possess a Shine-Dalgarno sequence, suggesting that such ncRNAs may encode small proteins instead of being solely non-coding. To support that the RIBOseq signals are reflecting translation, we tested the ribosomal-footprint covered ORF of ryhB and found a phenotype for the encoded peptide in iron-limiting condition. CONCLUSION: Determination of the RCV is a useful approach for a rapid first-step differentiation between bacterial ncRNAs and small mRNAs. Further, many known ncRNAs may encode proteins as well.


Assuntos
Escherichia coli O157/genética , Peptídeos/genética , Pequeno RNA não Traduzido/genética , Ribossomos/genética , Análise de Sequência de RNA , Sequência de Bases , Perfilação da Expressão Gênica , Fenótipo
6.
BMC Genomics ; 17: 133, 2016 Feb 24.
Artigo em Inglês | MEDLINE | ID: mdl-26911138

RESUMO

BACKGROUND: Genomes of E. coli, including that of the human pathogen Escherichia coli O157:H7 (EHEC) EDL933, still harbor undetected protein-coding genes which, apparently, have escaped annotation due to their small size and non-essential function. To find such genes, global gene expression of EHEC EDL933 was examined, using strand-specific RNAseq (transcriptome), ribosomal footprinting (translatome) and mass spectrometry (proteome). RESULTS: Using the above methods, 72 short, non-annotated protein-coding genes were detected. All of these showed signals in the ribosomal footprinting assay indicating mRNA translation. Seven were verified by mass spectrometry. Fifty-seven genes are annotated in other enterobacteriaceae, mainly as hypothetical genes; the remaining 15 genes constitute novel discoveries. In addition, protein structure and function were predicted computationally and compared between EHEC-encoded proteins and 100-times randomly shuffled proteins. Based on this comparison, 61 of the 72 novel proteins exhibit predicted structural and functional features similar to those of annotated proteins. Many of the novel genes show differential transcription when grown under eleven diverse growth conditions suggesting environmental regulation. Three genes were found to confer a phenotype in previous studies, e.g., decreased cattle colonization. CONCLUSIONS: These findings demonstrate that ribosomal footprinting can be used to detect novel protein coding genes, contributing to the growing body of evidence that hypothetical genes are not annotation artifacts and opening an additional way to study their functionality. All 72 genes are taxonomically restricted and, therefore, appear to have evolved relatively recently de novo.


Assuntos
Escherichia coli O157/genética , Evolução Molecular , Genes Bacterianos , Proteoma/genética , Transcriptoma , Animais , Bovinos , Biologia Computacional , Proteínas de Escherichia coli/genética , Espectrometria de Massas , Fenótipo , RNA Bacteriano/genética , Análise de Sequência de RNA
7.
BMC Evol Biol ; 15: 283, 2015 Dec 18.
Artigo em Inglês | MEDLINE | ID: mdl-26677845

RESUMO

BACKGROUND: Gene duplication is believed to be the classical way to form novel genes, but overprinting may be an important alternative. Overprinting allows entirely novel proteins to evolve de novo, i.e., formerly non-coding open reading frames within functional genes become expressed. Only three cases have been described for Escherichia coli. Here, a fourth example is presented. RESULTS: RNA sequencing revealed an open reading frame weakly transcribed in cow dung, coding for 101 residues and embedded completely in the -2 reading frame of citC in enterohemorrhagic E. coli. This gene is designated novel overlapping gene, nog1. The promoter region fused to gfp exhibits specific activities and 5' rapid amplification of cDNA ends indicated the transcriptional start 40-bp upstream of the start codon. nog1 was strand-specifically arrested in translation by a nonsense mutation silent in citC. This Nog1-mutant showed a phenotype in competitive growth against wild type in the presence of MgCl2. Small differences in metabolite concentrations were also found. Bioinformatic analyses propose Nog1 to be inner membrane-bound and to possess at least one membrane-spanning domain. A phylogenetic analysis suggests that the orphan gene nog1 arose by overprinting after Escherichia/Shigella separated from the other γ-proteobacteria. CONCLUSIONS: Since nog1 is of recent origin, non-essential, short, weakly expressed and only marginally involved in E. coli's central metabolism, we propose that this gene is in an initial stage of evolution. While we present specific experimental evidence for the existence of a fourth overlapping gene in enterohemorrhagic E. coli, we believe that this may be an initial finding only and overlapping genes in bacteria may be more common than is currently assumed by microbiologists.


Assuntos
Escherichia coli Enteropatogênica/genética , Evolução Molecular , Animais , Proteínas de Bactérias/genética , Sequência de Bases , Bovinos , Códon de Iniciação , Biologia Computacional , Escherichia coli Enteropatogênica/classificação , Escherichia coli Enteropatogênica/crescimento & desenvolvimento , Fezes/microbiologia , Homologia de Genes , Dados de Sequência Molecular , Fases de Leitura Aberta , Óperon , Filogenia , Regiões Promotoras Genéticas , Shigella/genética
8.
BMC Genomics ; 15: 353, 2014 May 09.
Artigo em Inglês | MEDLINE | ID: mdl-24885796

RESUMO

BACKGROUND: Multiple infection sources for enterohemorrhagic Escherichia coli O157:H7 (EHEC) are known, including animal products, fruit and vegetables. The ecology of this pathogen outside its human host is largely unknown and one third of its annotated genes are still hypothetical. To identify genetic determinants expressed under a variety of environmental factors, we applied strand-specific RNA-sequencing, comparing the SOLiD and Illumina systems. RESULTS: Transcriptomes of EHEC were sequenced under 11 different biotic and abiotic conditions: LB medium at pH4, pH7, pH9, or at 15°C; LB with nitrite or trimethoprim-sulfamethoxazole; LB-agar surface, M9 minimal medium, spinach leaf juice, surface of living radish sprouts, and cattle feces. Of 5379 annotated genes in strain EDL933 (genome and plasmid), a surprising minority of only 144 had null sequencing reads under all conditions. We therefore developed a statistical method to distinguish weakly transcribed genes from background transcription. We find that 96% of all genes and 91.5% of the hypothetical genes exhibit a significant transcriptional signal under at least one condition. Comparing SOLiD and Illumina systems, we find a high correlation between both approaches for fold-changes of the induced or repressed genes. The pathogenicity island LEE showed highest transcriptional activity in LB medium, minimal medium, and after treatment with antibiotics. Unique sets of genes, including many hypothetical genes, are highly up-regulated on radish sprouts, cattle feces, or in the presence of antibiotics. Furthermore, we observed induction of the shiga-toxin carrying phages by antibiotics and confirmed active biofilm related genes on radish sprouts, in cattle feces, and on agar plates. CONCLUSIONS: Since only a minority of genes (2.7%) were not active under any condition tested (null reads), we suggest that the assumption of significant genome over-annotations is wrong. Environmental transcriptomics uncovered hitherto unknown gene functions and unique regulatory patterns in EHEC. For instance, the environmental function of azoR had been elusive, but this gene is highly active on radish sprouts. Thus, NGS-transcriptomics is an appropriate technique to propose new roles of hypothetical genes and to guide future research.


Assuntos
Escherichia coli O157/genética , Fezes/microbiologia , Raphanus/microbiologia , Transcriptoma , Animais , Antibacterianos/farmacologia , Bovinos , Escherichia coli O157/isolamento & purificação , Escherichia coli O157/metabolismo , Proteínas de Escherichia coli/genética , Biblioteca Gênica , Sequenciamento de Nucleotídeos em Larga Escala , Humanos , Concentração de Íons de Hidrogênio , Raphanus/genética , Raphanus/metabolismo , Análise de Sequência de RNA , Transcriptoma/efeitos dos fármacos , Fatores de Virulência/genética , Fatores de Virulência/metabolismo
9.
IEEE Trans Vis Comput Graph ; 30(1): 869-879, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-37874714

RESUMO

Optimal ski route selection is a challenge based on a multitude of factors, such as the steepness, compass direction, or crowdedness. The personal preferences of every skier towards these factors require individual adaptations, which aggravate this task. Current approaches within this domain do not combine automated routing capabilities with user preferences, missing out on the possibility of integrating domain knowledge in the analysis process. We introduce SkiVis, a visual analytics application to interactively explore ski slopes and provide routing recommendations based on user preferences. In collaboration with ski guides and enthusiasts, we elicited requirements and guidelines for such an application and propose different workflows depending on the skiers' familiarity with the resort. In a case study on the resort of Ski Arlberg, we illustrate how to leverage volunteered geographic information to enable a numerical comparison between slopes. We evaluated our approach through a pair-analytics study and demonstrate how it supports skiers in discovering relevant and preference-based ski routes. Besides the tasks investigated in the study, we derive additional use cases from the interviews that showcase the further potential of SkiVis, and contribute directions for further research opportunities.

10.
Artigo em Inglês | MEDLINE | ID: mdl-38656864

RESUMO

Treemaps are a powerful tool for representing hierarchical data in a space-efficient manner and are used in various domains, including network security or software development. However, interpreting the topology encoded by nested rectangles can be challenging, particularly compared to tree-structured representations like node-link diagrams or icicle plots. To address this challenge, we introduce TreEducation, a visual education platform designed to improve the visualization literacy skills required for reading treemaps among non-expert users. TreEducation is an online application that combines visualizations, interactions, and gamification elements to facilitate understanding of eight different treemap layout algorithms and enhance students' learning process. We evaluated TreEducation in a classroom setting and a controlled environment. Our results indicate a significant knowledge gain of students training exclusively with TreEducation and the usefulness of competition as a social gamification element included in our competitive quiz.

11.
IEEE Trans Vis Comput Graph ; 30(6): 2929-2941, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38625781

RESUMO

Scatter plots are popular for displaying 2D data, but in practice, many data sets have more than two dimensions. For the analysis of such multivariate data, it is often necessary to switch between scatter plots of different dimension pairs, e.g., in a scatter plot matrix (SPLOM). Alternative approaches include a "grand tour" for an overview of the entire data set or creating artificial axes from dimensionality reduction (DR). A cross-cutting concern in all techniques is the ability of viewers to find correspondence between data points in different views. Previous work proposed animations to preserve the mental map between view changes and to trace points as well as clusters between scatter plots of the same underlying data set. In this article, we evaluate a variety of spline- and rotation-based view transitions in a crowdsourced user study focusing on ecological validity. Using the study results, we assess each animation's suitability for tracing points and clusters across view changes. We evaluate whether the order of horizontal and vertical rotation is relevant for task accuracy. The results show that rotations with an orthographic camera or staged expansion of a depth axis significantly outperform all other animation techniques for the traceability of individual points. Further, we provide a ranking of the animated transition techniques for traceability of individual points. However, we could not find any significant differences for the traceability of clusters. Furthermore, we identified differences by animation direction that could guide further studies to determine potential confounds for these differences. We publish the study data for reuse and provide the animation framework as a D3.js plug-in.

12.
Artigo em Inglês | MEDLINE | ID: mdl-37342951

RESUMO

With the surge of data-driven analysis techniques, there is a rising demand for enhancing the exploration of large high-dimensional data by enabling interactions for the joint analysis of features (i.e., dimensions). Such a dual analysis of the feature space and data space is characterized by three components, (1) a view visualizing feature summaries, (2) a view that visualizes the data records, and (3) a bidirectional linking of both plots triggered by human interaction in one of both visualizations, e.g., Linking & Brushing. Dual analysis approaches span many domains, e.g., medicine, crime analysis, and biology. The proposed solutions encapsulate various techniques, such as feature selection or statistical analysis. However, each approach establishes a new definition of dual analysis. To address this gap, we systematically reviewed published dual analysis methods to investigate and formalize the key elements, such as the techniques used to visualize the feature space and data space, as well as the interaction between both spaces. From the information elicited during our review, we propose a unified theoretical framework for dual analysis, encompassing all existing approaches extending the field. We apply our proposed formalization describing the interactions between each component and relate them to the addressed tasks. Additionally, we categorize the existing approaches using our framework and derive future research directions to advance dual analysis by including state-of-the-art visual analysis techniques to improve data exploration.

13.
IEEE Trans Vis Comput Graph ; 29(4): 1920-1936, 2023 04.
Artigo em Inglês | MEDLINE | ID: mdl-34898435

RESUMO

Coaches and analysts prepare for upcoming matches by identifying common patterns in the positioning and movement of the competing teams in specific situations. Existing approaches in this domain typically rely on manual video analysis and formation discussion using whiteboards; or expert systems that rely on state-of-the-art video and trajectory visualization techniques and advanced user interaction. We bridge the gap between these approaches by contributing a light-weight, simplified interaction and visualization system, which we conceptualized in an iterative design study with the coaching team of a European first league soccer team. Our approach is walk-up usable by all domain stakeholders, and at the same time, can leverage advanced data retrieval and analysis techniques: a virtual magnetic tactic-board. Users place and move digital magnets on a virtual tactic-board, and these interactions get translated to spatio-temporal queries, used to retrieve relevant situations from massive team movement data. Despite such seemingly imprecise query input, our approach is highly usable, supports quick user exploration, and retrieval of relevant results via query relaxation. Appropriate simplified result visualization supports in-depth analyses to explore team behavior, such as formation detection, movement analysis, and what-if analysis. We evaluated our approach with several experts from European first league soccer clubs. The results show that our approach makes the complex analytical processes needed for the identification of tactical behavior directly accessible to domain experts for the first time, demonstrating our support of coaches in preparation for future encounters.


Assuntos
Desempenho Atlético , Futebol , Gráficos por Computador , Movimento , Caminhada
14.
IEEE Comput Graph Appl ; 43(5): 83-90, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37713213

RESUMO

In the past two decades, research in visual analytics (VA) applications has made tremendous progress, not just in terms of scientific contributions, but also in real-world impact across wide-ranging domains including bioinformatics, urban analytics, and explainable AI. Despite these success stories, questions on the rigor and value of VA application research have emerged as a grand challenge. This article outlines a research and development agenda for making VA application research more rigorous and impactful. We first analyze the characteristics of VA application research and explain how they cause the rigor and value problem. Next, we propose a research ecosystem for improving scientific value, and rigor and outline an agenda with 12 open challenges spanning four areas, including foundation, methodology, application, and community. We encourage discussions, debates, and innovative efforts toward more rigorous and impactful VA research.

15.
IEEE Trans Vis Comput Graph ; 28(12): 4918-4929, 2022 12.
Artigo em Inglês | MEDLINE | ID: mdl-34478370

RESUMO

Multiscale visualizations are typically used to analyze multiscale processes and data in various application domains, such as the visual exploration of hierarchical genome structures in molecular biology. However, creating such multiscale visualizations remains challenging due to the plethora of existing work and the expression ambiguity in visualization research. Up to today, there has been little work to compare and categorize multiscale visualizations to understand their design practices. In this article, we present a structured literature analysis to provide an overview of common design practices in multiscale visualization research. We systematically reviewed and categorized 122 published journal or conference articles between 1995 and 2020. We organized the reviewed articles in a taxonomy that reveals common design factors. Researchers and practitioners can use our taxonomy to explore existing work to create new multiscale navigation and visualization techniques. Based on the reviewed articles, we examine research trends and highlight open research challenges.


Assuntos
Gráficos por Computador
16.
IEEE Trans Vis Comput Graph ; 28(12): 4757-4769, 2022 12.
Artigo em Inglês | MEDLINE | ID: mdl-34379592

RESUMO

We present VisInReport, a visual analytics tool that supports the manual analysis of discourse transcripts and generates reports based on user interaction. As an integral part of scholarly work in the social sciences and humanities, discourse analysis involves an aggregation of characteristics identified in the text, which, in turn, involves a prior identification of regions of particular interest. Manual data evaluation requires extensive effort, which can be a barrier to effective analysis. Our system addresses this challenge by augmenting the users' analysis with a set of automatically generated visualization layers. These layers enable the detection and exploration of relevant parts of the discussion supporting several tasks, such as topic modeling or question categorization. The system summarizes the extracted events visually and verbally, generating a content-rich insight into the data and the analysis process. During each analysis session, VisInReport builds a shareable report containing a curated selection of interactions and annotations generated by the analyst. We evaluate our approach on real-world datasets through a qualitative study with domain experts from political science, computer science, and linguistics. The results highlight the benefit of integrating the analysis and reporting processes through a visual analytics system, which supports the communication of results among collaborating researchers.


Assuntos
Gráficos por Computador
17.
IEEE Trans Vis Comput Graph ; 28(11): 3651-3661, 2022 11.
Artigo em Inglês | MEDLINE | ID: mdl-36048995

RESUMO

Networks are an important means for the representation and analysis of data in a variety of research and application areas. While there are many efficient methods to create layouts for networks to support their visual analysis, approaches for the comparison of networks are still underexplored. Especially when it comes to the comparison of weighted networks, which is an important task in several areas, such as biology and biomedicine, there is a lack of efficient visualization approaches. With the availability of affordable high-quality virtual reality (VR) devices, such as head-mounted displays (HMDs), the research field of immersive analytics emerged and showed great potential for using the new technology for visual data exploration. However, the use of immersive technology for the comparison of networks is still underexplored. With this work, we explore how weighted networks can be visually compared in an immersive VR environment and investigate how visual representations can benefit from the extended 3D design space. For this purpose, we develop different encodings for 3D node-link diagrams supporting the visualization of two networks within a single representation and evaluate them in a pilot user study. We incorporate the results into a more extensive user study comparing node-link representations with matrix representations encoding two networks simultaneously. The data and tasks designed for our experiments are similar to those occurring in real-world scenarios. Our evaluation shows significantly better results for the node-link representations, which is contrary to comparable 2D experiments and indicates a high potential for using VR for the visual comparison of networks.


Assuntos
Óculos Inteligentes , Realidade Virtual , Gráficos por Computador , Projetos Piloto
18.
IEEE Trans Vis Comput Graph ; 28(9): 3307-3323, 2022 09.
Artigo em Inglês | MEDLINE | ID: mdl-33439846

RESUMO

Visual analytics enables the coupling of machine learning models and humans in a tightly integrated workflow, addressing various analysis tasks. Each task poses distinct demands to analysts and decision-makers. In this survey, we focus on one canonical technique for rule-based classification, namely decision tree classifiers. We provide an overview of available visualizations for decision trees with a focus on how visualizations differ with respect to 16 tasks. Further, we investigate the types of visual designs employed, and the quality measures presented. We find that (i) interactive visual analytics systems for classifier development offer a variety of visual designs, (ii) utilization tasks are sparsely covered, (iii) beyond classifier development, node-link diagrams are omnipresent, (iv) even systems designed for machine learning experts rarely feature visual representations of quality measures other than accuracy. In conclusion, we see a potential for integrating algorithmic techniques, mathematical quality measures, and tailored interactive visualizations to enable human experts to utilize their knowledge more effectively.


Assuntos
Algoritmos , Gráficos por Computador , Árvores de Decisões , Humanos , Aprendizado de Máquina
19.
IEEE Trans Vis Comput Graph ; 27(3): 2220-2236, 2021 03.
Artigo em Inglês | MEDLINE | ID: mdl-31514139

RESUMO

Visualization has been deemed a useful technique by researchers and practitioners, alike, leaving a trail of arguments behind that reason why visualization works. In addition, examples of misleading usages of visualizations in information communication have occasionally been pointed out. Thus, to contribute to the fundamental understanding of our discipline, we require a comprehensive collection of arguments on "why visualize?" (or "why not?"), untangling the rationale behind positive and negative viewpoints. In this paper, we report a theoretical study to understand the underlying reasons of various arguments; their relationships (e.g., built-on, and conflict); and their respective dependencies on tasks, users, and data. We curated an argumentative network based on a collection of arguments from various fields, including information visualization, cognitive science, psychology, statistics, philosophy, and others. Our work proposes several categorizations for the arguments, and makes their relations explicit. We contribute the first comprehensive and systematic theoretical study of the arguments on visualization. Thereby, we provide a roadmap towards building a foundation for visualization theory and empirical research as well as for practical application in the critique and design of visualizations. In addition, we provide our argumentation network and argument collection online at https://whyvis.dbvis.de, supported by an interactive visualization.

20.
IEEE Trans Vis Comput Graph ; 27(2): 517-527, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33048714

RESUMO

The overview-driven visual analysis of large-scale dynamic graphs poses a major challenge. We propose Multiscale Snapshots, a visual analytics approach to analyze temporal summaries of dynamic graphs at multiple temporal scales. First, we recursively generate temporal summaries to abstract overlapping sequences of graphs into compact snapshots. Second, we apply graph embeddings to the snapshots to learn low-dimensional representations of each sequence of graphs to speed up specific analytical tasks (e.g., similarity search). Third, we visualize the evolving data from a coarse to fine-granular snapshots to semi-automatically analyze temporal states, trends, and outliers. The approach enables us to discover similar temporal summaries (e.g., reoccurring states), reduces the temporal data to speed up automatic analysis, and to explore both structural and temporal properties of a dynamic graph. We demonstrate the usefulness of our approach by a quantitative evaluation and the application to a real-world dataset.

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