Detalhe da pesquisa
1.
Erythrocyte adenosine A2B receptor prevents cognitive and auditory dysfunction by promoting hypoxic and metabolic reprogramming.
PLoS Biol
; 19(6): e3001239, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34138843
2.
Erythrocyte ENT1-AMPD3 Axis is an Essential Purinergic Hypoxia Sensor and Energy Regulator Combating CKD in a Mouse Model.
J Am Soc Nephrol
; 34(10): 1647-1671, 2023 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37725437
3.
p97 dysfunction underlies a loss of quality control of damaged membrane proteins and promotes oxidative stress and sickling in sickle cell disease.
FASEB J
; 36(5): e22246, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35405035
4.
Erythrocyte Metabolic Reprogramming by Sphingosine 1-Phosphate in Chronic Kidney Disease and Therapies.
Circ Res
; 127(3): 360-375, 2020 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32284030
5.
Adenosine A2B receptor: A pathogenic factor and a therapeutic target for sensorineural hearing loss.
FASEB J
; 34(12): 15771-15787, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33131093
6.
Reciprocal upregulation of hypoxia-inducible factor-1α and persistently enhanced placental adenosine signaling contribute to the pathogenesis of preeclampsia.
FASEB J
; 34(3): 4041-4054, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31930569
7.
Circadian period 2: a missing beneficial factor in sickle cell disease by lowering pulmonary inflammation, iron overload, and mortality.
FASEB J
; 33(9): 10528-10537, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31260634
8.
Erythrocyte Adenosine A2B Receptor-Mediated AMPK Activation: A Missing Component Counteracting CKD by Promoting Oxygen Delivery.
J Am Soc Nephrol
; 30(8): 1413-1424, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31278195
9.
Sphingosine-1-phosphate receptor 1 mediates elevated IL-6 signaling to promote chronic inflammation and multitissue damage in sickle cell disease.
FASEB J
; 32(5): 2855-2865, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29401601
10.
Beneficial Role of Erythrocyte Adenosine A2B Receptor-Mediated AMP-Activated Protein Kinase Activation in High-Altitude Hypoxia.
Circulation
; 134(5): 405-21, 2016 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27482003
11.
Elevated adenosine signaling via adenosine A2B receptor induces normal and sickle erythrocyte sphingosine kinase 1 activity.
Blood
; 125(10): 1643-52, 2015 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25587035
12.
Elevated placental adenosine signaling contributes to the pathogenesis of preeclampsia.
Circulation
; 131(8): 730-41, 2015 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25538227
13.
A pre-eclampsia-associated Epstein-Barr virus antibody cross-reacts with placental GPR50.
Clin Immunol
; 168: 64-71, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27181993
14.
Excess adenosine A2B receptor signaling contributes to priapism through HIF-1α mediated reduction of PDE5 gene expression.
FASEB J
; 28(6): 2725-35, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24614760
15.
Angiotensin receptor agonistic autoantibodies and hypertension: preeclampsia and beyond.
Circ Res
; 113(1): 78-87, 2013 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23788505
16.
Elevated ecto-5'-nucleotidase-mediated increased renal adenosine signaling via A2B adenosine receptor contributes to chronic hypertension.
Circ Res
; 112(11): 1466-78, 2013 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-23584256
17.
Autoantibody-mediated IL-6-dependent endothelin-1 elevation underlies pathogenesis in a mouse model of preeclampsia.
J Immunol
; 186(10): 6024-34, 2011 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21482739
18.
A2B adenosine receptor contributes to penile erection via PI3K/AKT signaling cascade-mediated eNOS activation.
FASEB J
; 25(8): 2823-30, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21566208
19.
A2B adenosine receptor-mediated induction of IL-6 promotes CKD.
J Am Soc Nephrol
; 22(5): 890-901, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21511827
20.
Erythrocyte transglutaminase-2 combats hypoxia and chronic kidney disease by promoting oxygen delivery and carnitine homeostasis.
Cell Metab
; 34(2): 299-316.e6, 2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35108516