The healing effects of a topical phytogenic ointment on insect bite hypersensitivity lesions in horses.

Insect bite hypersensitivity (IBH) is the most common cause of pruritus in horses and is a serious welfare issue for affected animals. In this study, the effect of a topical phytogenic ointment on the healing of cutaneous lesions was investigated in a double-blind trial involving 26 horses with I B H. The number of lesions and their total surface area were recorded on days 0, 7, and 21 in horses treated for 3 weeks with either verum or placebo ointment. After unblinding of treatment assignment, the horses that had been treated with the placebo ointment received the verum preparation for an additional 3 weeks and the number of lesions and their total surface area were again recorded. This part of the study was not blinded. The number of lesions and the total surface area decreased in both treatment groups (no significant difference). Owners also scored the degree of discomfort suffered by their horses as a result of IBH lesions, and at the end of the 3-week period this score was significantly lower in the verum than in the placebo group (P = 0.04). When placebo-treated horses subsequently received the verum ointment, their wound severity score also decreased significantly (P < 0.01). Daily application of an ointment (verum or placebo) does not cure IBH, but use of the phytogenic ointment led to a decrease in the owner-assessed discomfort suffered by horses.

Edge profile analysis of Joint European Torus (JET) Thomson scattering data: Quantifying the systematic error due to edge localised mode synchronisation.

The Joint European Torus (JET) high resolution Thomson scattering (HRTS) system measures radial electron temperature and density profiles. One of the key capabilities of this diagnostic is measuring the steep pressure gradient, termed the pedestal, at the edge of JET plasmas. The pedestal is susceptible to limiting instabilities, such as Edge Localised Modes (ELMs), characterised by a periodic collapse of the steep gradient region. A common method to extract the pedestal width, gradient, and height, used on numerous machines, is by performing a modified hyperbolic tangent (mtanh) fit to overlaid profiles selected from the same region of the ELM cycle. This process of overlaying profiles, termed ELM synchronisation, maximises the number of data points defining the pedestal region for a given phase of the ELM cycle. When fitting to HRTS profiles, it is necessary to incorporate the diagnostic radial instrument function, particularly important when considering the pedestal width. A deconvolved fit is determined by a forward convolution method requiring knowledge of only the instrument function and profiles. The systematic error due to the deconvolution technique incorporated into the JET pedestal fitting tool has been documented by Frassinetti et al. [Rev. Sci. Instrum. 83, 013506 (2012)]. This paper seeks to understand and quantify the systematic error introduced to the pedestal width due to ELM synchronisation. Synthetic profiles, generated with error bars and point-to-point variation characteristic of real HRTS profiles, are used to evaluate the deviation from the underlying pedestal width. We find on JET that the ELM synchronisation systematic error is negligible in comparison to the statistical error when assuming ten overlaid profiles (typical for a pre-ELM fit to HRTS profiles). This confirms that fitting a mtanh to ELM synchronised profiles is a robust and practical technique for extracting the pedestal structure.

Phillips-Tikhonov regularization with a priori information for neutron emission tomographic reconstruction on Joint European Torus.

A method of tomographic reconstruction of the neutron emissivity in the poloidal cross section of the Joint European Torus (JET, Culham, UK) tokamak was developed. Due to very limited data set (two projection angles, 19 lines of sight only) provided by the neutron emission profile monitor (KN3 neutron camera), the reconstruction is an ill-posed inverse problem. The aim of this work consists in making a contribution to the development of reliable plasma tomography reconstruction methods that could be routinely used at JET tokamak. The proposed method is based on Phillips-Tikhonov regularization and incorporates a priori knowledge of the shape of normalized neutron emissivity profile. For the purpose of the optimal selection of the regularization parameters, the shape of normalized neutron emissivity profile is approximated by the shape of normalized electron density profile measured by LIDAR or high resolution Thomson scattering JET diagnostics. In contrast with some previously developed methods of ill-posed plasma tomography reconstruction problem, the developed algorithms do not include any post-processing of the obtained solution and the physical constrains on the solution are imposed during the regularization process. The accuracy of the method is at first evaluated by several tests with synthetic data based on various plasma neutron emissivity models (phantoms). Then, the method is applied to the neutron emissivity reconstruction for JET D plasma discharge #85100. It is demonstrated that this method shows good performance and reliability and it can be routinely used for plasma neutron emissivity reconstruction on JET.

Note: statistical errors estimation for Thomson scattering diagnostics.

A practical way of estimating statistical errors of a Thomson scattering diagnostic measuring plasma electron temperature and density is described. Analytically derived expressions are successfully tested with Monte Carlo simulations and implemented in an automatic data processing code of the JET LIDAR diagnostic.

Spatial resolution of the JET Thomson scattering system.

The instrument function of the high resolution Thomson scattering (HRTS) diagnostic in the Joint European Torus (JET) has been calculated for use in improved pedestal profile analysis. The full width at half maximum (FWHM) of the spatial instrument response is (22 ± 1) mm for the original HRTS system configuration and depends on the particular magnetic topology of the JET plasmas. An improvement to the optical design of the laser input system is presented. The spatial smearing across magnetic flux surfaces is reduced in this design. The new input system has been implemented (from JPN 78742, July 2009) and the HRTS instrument function corresponding to the new configuration has been improved to approximately FWHM = (9.8 ± 0.8) mm. The reconstructed instrument kernels are used in combination with an ad hoc forward deconvolution procedure for pedestal analysis. This procedure produces good results for both the old and new setups, but the reliability of the deconvolved profiles is greatly reduced when the pedestal width is of the same order as, or less than the FWHM of the instrument kernel.

Detection of dust on JET with the high resolution Thomson scattering system.

Dust particles have been observed with Thomson scattering systems on several tokamaks. We present here the first evidence of dust particles observed by the new high resolution Thomson scattering system on JET. The system consists of filter spectrometers that analyze the Thomson scattering spectrum from 670 to 1050 nm in four spectral channels. The laser source is a 5 J Q-switched Nd:YAG laser. Without a spectral channel at the laser wavelength, only dust particles that emit broadband light could be detected; these particles have been observed on JET after disruptions. The timing of their emission is clearly different from that expected for a Thomson scattering pulse. The light pulse from dust happens after the peak of the laser light and has a long tail.

Absolute calibration of LIDAR Thomson scattering systems by rotational Raman scattering.

Absolute calibration of LIDAR Thomson scattering systems on large fusion devices may be achieved using rotational Raman scattering. The choice of calibrating gas molecule presents different options and design trade-offs and is likely to be strongly dependent on the laser wavelength selected. Raman scattering of hydrogenic molecules produces a very broad spectrum, however, with far fewer scattered photons than scattering from nitrogen or oxygen at the same gas pressure. Lower laser wavelengths have the advantage that the Raman cross section increases, sigma(Raman) proportional to 1/lambda(0)(4), but the disadvantage that the spectral width of the scattered spectrum decreases, Deltalambda(Raman) proportional to lambda(0)(2). This narrower spectrum makes measurement closer to the laser wavelength necessary. The design of the calibration technique presents a number of challenges. Some of these challenges are generic to all Thomson scattering systems. These include detecting a sufficient number of photoelectrons and designing filters that measure close to the laser wavelength while simultaneously achieving adequate blocking of the laser wavelength. An issue specific to LIDAR systems arises since the collection optics operates over a wide range of depth of field. This wide depth of field has the effect of changing the angle of light incident on the optical interference filter with plasma major radius. The angular distribution then determines the effective spectral transmission function of the interference filter and hence impacts on the accuracy of the absolute calibration. One method that can be used to increase absolute calibration accuracy is collecting both Stokes and anti-Stokes lines with optical filter transmission bands specifically designed to reduce systematic uncertainty.

Laser beam combiner for Thomson scattering core LIDAR.

The light detection and ranging Thomson scattering (TS) diagnostic is advantageous since it only requires a single view port into the tokamak. This technique requires a short pulse laser at high energy, usually showing a limited repetition rate. Having multiple lasers will increase the repetition rate. This paper presents a scanning mirror as a laser beam combiner. Measurements of the position accuracy and jitter show that the pointing stability of the laser beam is within ±25 µrad for over tens of seconds. A control feedback loop is implemented to demonstrate the long term stability. Such a system could be applied for ITER and JET.

ITER LIDAR performance analysis.

The core LIDAR Thomson scattering for ITER is specified for core profile measurements with a spatial resolution of 7 cm (a/30) for the range of 500 eV3x10(19) m(-3) at an accuracy of <10% for T(e). These specifications are verified using a full profile Monte Carlo simulation code. In the simulations it is assumed that the input transmission is 50% and the collection transmission is 10% for lambda=300-1200 nm and F/#=6-17. A crucial design decision lies on the choice of laser and detector combination. It is evaluated that the system can meet its spatial and accuracy specifications for higher temperatures of T(e)>5 keV with a combination of a neodymium-doped yttrium aluminum garnet (Nd:YAG) laser (lambda(0)=1064 nm, Delta lambda<1 nm, 5 J, and Delta t(FWHM)=250 ps, 5-10 Hz) and S20, GaAs, and GaAsP microchannel plate photomultipliers (Delta t(FWHM)<300 ps, effective quantum efficiency, EQE=3%-4%, and D=18 mm). In order to reach the required T(e) of 500 eV with Nd:YAG first harmonic, this choice requires a development of fast near infrared detectors.

Enhancement of the JET edge LIDAR Thomson scattering diagnostic with ultrafast detectors.

The edge light detection and ranging (LIDAR) Thomson scattering diagnostic at the Joint European Torus fusion experiment uses a 3 J ruby laser to measure the electron density and temperature profile at the plasma edge. The original system used a 1 GHz digitizer and detectors with response times of approximately 650 ps and effective quantum efficiencies <7%. This system has recently been enhanced with the installation of a new 8 GHz digitizer and four new ultrafast GaAsP microchannel plate photomultiplier tube detectors with response times of <300 ps and effective quantum efficiencies in the range of approximately 13%-20% (averaged over lambda=500-700 nm). This upgrade has enabled the spatial resolution to be reduced to approximately 6.3 cm along the laser line of sight for a laser pulse of 300 ps full width at half maximum, which is close to the requirements for the ITER core LIDAR. Performance analysis shows that the new system will have an effective spatial resolution of up to 1 cm in the magnetic midplane via magnetic flux surface mapping.